A5048940765- Lipoproteins and Cardiovascular Health
- Paraoxonase enzyme and polymorphisms
- Adipokines, Inflammation, and Metabolic Diseases
- Diabetes, Cardiovascular Risks, and Lipoproteins
- Cholesterol and Lipid Metabolism
- Birth, Development, and Health
- Cancer, Lipids, and Metabolism
- Pregnancy and preeclampsia studies
- Biomarkers in Disease Mechanisms
- Dialysis and Renal Disease Management
- Apelin-related biomedical research
- Cardiovascular Disease and Adiposity
- Cynara cardunculus studies
- Pancreatitis Pathology and Treatment
- Liver Disease Diagnosis and Treatment
- Hormonal Regulation and Hypertension
- Blood Pressure and Hypertension Studies
- Gestational Diabetes Research and Management
- Diabetes and associated disorders
- Obstructive Sleep Apnea Research
- Diabetes Management and Research
- Antioxidant Activity and Oxidative Stress
- Lipid metabolism and disorders
- Atherosclerosis and Cardiovascular Diseases
- Vitamin C and Antioxidants Research
University of Belgrade
2014-2023
Deleted Institution
2019-2023
Centar za Promociju Nauke
2011
Institute of Biochemistry
1999-2007
Inštitut Bion
2002-2003
Zdravstveni centar
2002
Background: Cadmium and lead are widespread non-biodegradable pollutants of great concern to human health. In real life scenarios, we exposed mixtures chemicals rather than single chemicals, it is therefore paramount importance assess their toxicity. this study, investigated the toxicity Cd Pb alone as a mixture in an animal model acute exposure. Methods: Experimental groups received treatment aqueous solution Cd-chloride (15 30 mg/kg body weight (b.w.) Pb-acetate (150 b.w.), while group 15...
Friedewald's formula for the estimation of LDL-C concentration is most often used in clinical practice. A recent by Anandaraja and colleagues still needs to be evaluated before it extensively applied diagnosis. In present study we validated existing formulas derived a more accurate determine Serbian population. Our included 2053 patients with TG ≤ 4.52 mmol/L. an initial group 1010 patients, Anandaraja's were compared direct homogenous method determination. The obtained results allowed us...
We aimed to examine serum endocan level and the summary involvement of dyslipidemia, oxidative stress (OS) inflammation by calculation its comprehensive score (i.e. Dyslipidemia-Oxy-Inflammation (DOI) score) in relation glucoregulation subjects with prediabetes overt type 2 diabetes (T2D).
Abstract Background Alterations in plasma lipoprotein subclass distributions affect atherosclerosis risk. Smaller, denser low‐density (LDL) particles (sdLDL) are more susceptible to oxidation. In contrast, most of the protective effects high‐density lipoproteins (HDL) attributable larger particles. This study investigates connection between LDL and HDL particle heterogeneity oxidative stress, antioxidative defence (AOD) paraoxonase (PON1) status a healthy middle‐aged Serbian population....
Some cardiovascular complications in patients with chronic kidney disease and end-stage renal may be caused by structurally functionally modified lipoproteins. Redox status (advanced oxidation protein products [AOPPs]), prooxidant-antioxidant balance, total sulfhydryl (SH-groups), paraoxonase 1 (PON1) activity were assessed 77 20 controls. Lipoproteins isolated using ultracentrifugation. PON1, PON3, pentraxin-3 concentration determined enzyme-linked immunosorbent assay (ELISA)....
Abstract Polycystic ovary syndrome (PCOS) is associated with altered lipid profile and increased small, dense LDL particles (sdLDL). Considering that paraoxonase 1 (PON1) an antioxidative enzyme located on HDL particles, the aim of this study was to investigate connection between oxidative stress (OS) PON1 activity lipoprotein subclasses in PCOS depending obesity. In 115 patients, distributions were determined by gradient gel electrophoresis. OS status assessed total (TOS), advanced...
Preeclampsia (PE) is a pregnancy complication marked by hypertension (≥ 140/90 mmHg) and proteinuria 300 mg/24 h), with an unclear pathogenesis involving inflammation dyslipidemia. This study aimed to longitudinally examine changes in lipid status parameters inflammatory markers pregnant women at high risk for PE those who developed PE. Among 91 women, 20 (PE group), 71 were high-risk (HR group). Both groups monitored four points: T1-first, T2-, T3-third trimester, T4-pre-delivery. Lipid...
The objective of this prospective study was to evaluate whether soluble programmed cell death-1/programmed death-ligand 1 (PD-1/PD-L1) and serum amyloid A1 (SAA1) are potential diagnostic, predictive or prognostic biomarkers in lung cancer.Lung cancer patients (n=115) with advanced metastatic disease, 101 non-small cancer, NSCLC (77 EGFR wild-type on chemotherapy, 15 mutation positive adenocarcinoma patients, 9 mPD-L1 Expression ≥50% - responders immunotherapy), 14 small (SCLC) were...
Determination of lipoprotein size and subclasses distribution can provide more significant information on cardiovascular disease risk than measurement traditional lipid parameters alone. Accordingly, we aimed to examine their potential relationship with the novel biomarker endothelial dysfunction, such as endocan in patients type 2 diabetes mellitus (T2D), since there are no studies concerning this issue.This case-control study included a total 42 individuals T2D 64 diabetes-free...