A5052953246- Heavy Metal Exposure and Toxicity
- Effects and risks of endocrine disrupting chemicals
- Trace Elements in Health
- Heavy metals in environment
- Genomics, phytochemicals, and oxidative stress
- Computational Drug Discovery Methods
- Fluoride Effects and Removal
- Toxic Organic Pollutants Impact
- Air Quality and Health Impacts
- Animal testing and alternatives
- Aluminum toxicity and tolerance in plants and animals
- Carcinogens and Genotoxicity Assessment
- Pesticide Exposure and Toxicity
- Cholinesterase and Neurodegenerative Diseases
- SARS-CoV-2 and COVID-19 Research
- Mercury impact and mitigation studies
- Magnesium in Health and Disease
- Environmental Toxicology and Ecotoxicology
- Dental Health and Care Utilization
- Health, Environment, Cognitive Aging
- Synthesis and biological activity
- Pharmacogenetics and Drug Metabolism
- Agriculture Sustainability and Environmental Impact
- Free Radicals and Antioxidants
- Glutathione Transferases and Polymorphisms
University of Belgrade
2016-2025
University of Banja Luka
2021-2024
Deleted Institution
2014-2024
Institut za higijenu i tehnologiju mesa
2015
Sulforaphane (SFN), which is a hydrolysis product from glucoraphanin, compound found in cruciferous vegetables, has been studied for its potential health benefits, particularly disease prevention and treatment. SFN proven to be effective combating different types of cancer by inhibiting the proliferation tumors triggering apoptosis. This dual action demonstrated result reduction tumor size an enhancement survival rates animal models. also shown antidiabetic anti-obesity effects, improving...
Phthalates and bisphenol A, classified as endocrine disruptors, have weak estrogenic, anti-androgenic properties, affect thyroid hormone regulation. The aim of this study on male rats was to compare the subacute toxic effects low doses single compounds (bis (2 –ethylhexyl) phthalate (DEHP), dibutyl (DBP), A (BPA)) with their mixture through different biochemical, hormonal, hematological parameters. Rats were divided into five experimental groups: Control (corn oil), DEHP (50 mg/kg b.w./day),...
Recent data indicate that lead (Pb) can induce adverse effects even at low exposure levels. Moreover, the corresponding mechanisms of Pb toxicity have not been well identified. In liver and kidneys, was found to various toxic leading organ physiological disruption. Therefore, purpose study simulate low-dose in an animal model with aim assessing oxidative status essential element levels as main mechanism kidneys. Furthermore, dose–response modelling performed order determine benchmark dose...
Cancer is a leading cause of death worldwide, for which finding the optimal therapy remains an ongoing challenge. Drug resistance, toxic side effects, and lack specificity pose significant difficulties in traditional cancer treatments, to suboptimal clinical outcomes high mortality rates among patients. The need alternative therapies crucial, especially those resistant conventional methods like chemotherapy radiotherapy or patients where surgery not possible. Over past decade, novel approach...
Endocrine-disrupting chemicals (EDCs) are significant contributors to various detrimental conditions, mechanistically disrupting the endocrine system and causing adverse health effects. Mounting evidence suggests they can induce multigenerational transgenerational effects, yet awareness among individuals remains insufficient. This study aimed assess knowledge, attitudes, ways of informing moms in Serbia about disruptors based on information from 190 women Serbia. The research was conducted...
The main objective of this research was to conduct a dose–response modeling between the internal dose measured blood Cd, As, Hg, Ni, and Cr hormonal response serum testosterone, luteinizing hormone (LH), follicle-stimulating (FSH). study included 207 male participants from subjects 5 different cohorts (patients with prostate, testicular, pancreatic cancer, patients suffering various thyroid metabolic disorders, as well healthy volunteers), enrolled January 2019 May 2021 at Clinical Centre...
Exposure to low levels of a toxic metal lead (Pb) affects human health, and its effect as an endocrine disruptor has been reported. However, the precise role Pb in health is still unclear because no dose-response relationship established for such effect. The present study aimed examine blood (BLLs) relation serum free triiodothyronine (fT3), thyroxine (fT4), thyroid stimulating hormone (TSH), insulin 435 nonoccupationally exposed Serbian subjects (218 women, 217 men, 18-94 years age, mean...
The study was designed to investigate the influence of zinc (Zn) supplementation on cadmium-induced alterations in zinc, copper (Cu), and magnesium (Mg) status rabbits. For this purpose, concentrations cadmium (Cd), Zn, Cu, Mg were estimated blood, liver, kidney, bone. rabbits divided a control group, Cd group-animals intoxicated orally with (10 mg kg-1 bw, as aqueous solution Cd-chloride), Cd+Zn same dose co-treated Zn (20 Zn-sulphate). Solutions administered orally, every day for 28 days....