- Navier-Stokes equation solutions
- Advanced Mathematical Physics Problems
- Computational Fluid Dynamics and Aerodynamics
- Geometric Analysis and Curvature Flows
- Fluid Dynamics and Turbulent Flows
- Nonlinear Partial Differential Equations
- Gas Dynamics and Kinetic Theory
- Ferroptosis and cancer prognosis
- Solar and Space Plasma Dynamics
- Salivary Gland Disorders and Functions
- Stability and Controllability of Differential Equations
- Carbohydrate Chemistry and Synthesis
- Quantum, superfluid, helium dynamics
- High-Voltage Power Transmission Systems
- Cancer-related molecular mechanisms research
- Synthesis of Organic Compounds
- Calcium signaling and nucleotide metabolism
- Power Systems and Technologies
- Phosphorus and nutrient management
- Advanced Harmonic Analysis Research
- Smart Grid and Power Systems
- Eosinophilic Esophagitis
- Wastewater Treatment and Nitrogen Removal
- Thyroid Disorders and Treatments
- Telomeres, Telomerase, and Senescence
Henan University
2016-2025
Tianjin Medical University General Hospital
2022-2024
China General Nuclear Power Corporation (China)
2022-2024
Tianjin Medical University
2024
Tianjin Infectious Diseases Hospital
2024
Shanghai Jiao Tong University
2022-2023
Ruijin Hospital
2022-2023
University of Hong Kong - Shenzhen Hospital
2023
Peking University Shenzhen Hospital
2023
Henan Polytechnic University
2020
Ferroptosis is a newly discovered form of cell death that featured in wide range diseases. Exosome therapy promising therapeutic option has attracted much attention due to its low immunogenicity, toxicity, and ability penetrate biological barriers. In addition, emerging evidence indicates exosomes possess the modulate progression diverse diseases by regulating ferroptosis damaged cells. Hence, mechanism which cell-derived noncellular-derived target different through system Xc
Phosphate and pyrophosphate groups play a central role in cellular signalling consequently are of great interest to both medicinal chemists chemical biologists. However, the design molecules that can interfere with phosphate-based processes is recognised as significant challenge, especially when resulting compounds must show good penetration stability. Herein, we have reviewed full range phosphate bioisosteres currently reported provided context their deployment. We aim provide useful...
Primary Sjogren's syndrome (pSS) is a slowly progressive, inflammatory autoimmune disease characterized by lymphocytic infiltration into salivary and lacrimal glands. It becomes more recognized that morphology alterations of epithelial mitochondria are involved in altered cellular bioenergetics pSS patients. The integrated analysis the mitochondrial role pathogenesis aberrant immune microenvironment remains unknown.The mitochondria-related genes gene expression data were downloaded from...
Aging-related salivary dysfunction typically causes reduced saliva volumes, which leads to debilitating consequences, even affecting patient quality of life. Understanding the respective clinicopathological characteristics and molecular mechanisms underlying gland functioning during aging is vital for therapeutic purposes. Here, we provide a detailed atlas microenvironment aging, identified several phenotypes characteristic glands, including acini atrophy, increased inflammatory cells,...
In this paper, we derive an energy conservation criterion based on a combination of velocity and its gradient for the weak solutions both homogeneous incompressible Navier–Stokes equations general compressible equations. For case, class implies almost known corresponding results periodic domain via either or including famous Lions' obtained in [1, Rend. Semin. Mat. Univ. Padova, 30 (1960)]. helps us to extend previously criteria from fluid flow improve recent due Nguyen‐Nguyen‐Tang [26,...
Abstract Combating the accumulated senescent cells and healing of osteoporotic bone fractures in older remains a significant challenge. Nicotinamide mononucleotide (NMN), precursor NAD+, is an excellent candidate for mitigating aging-related disorders. However, it unknown if NMN can alleviate cell induction enhance fracture healing. Here we show that treatment partially reverses effects tumor necrosis factor-alpha (TNF-α) on human primary osteoblasts (HOBs): induction, diminished osteogenic...
To the Editor: Even to this day, etiology and pathogenesis of inflammatory bowel disease (IBD) are still unelucidated. Despite significant progress in IBD treatment recent years, some patients remain insensitive or non-responsive towards existing treatments. Therefore, further exploring develop novel therapeutic drugs drug combinations is quite necessary. Recent studies have demonstrated potential regulating cell death IBD. The ferroptosis, a form death, also involved pathological process...
In this paper, we prove that the 1D Cauchy problem of compressible Navier–Stokes equations admits a unique global classical solution (ρ,u) if viscosity μ(ρ)=1+ρβ with β⩾0. The initial data can be arbitrarily large and may contain vacuum. Some new weighted estimates density velocity are obtained when deriving higher order solution.
Primary Sjogren's syndrome (pSS) is a prototypical systemic autoimmune disease characterised by lymphocyte infiltration and immune-complex deposition in multiple organs. The specific distribution of immune cell populations their relationship with mitochondria remain unknown.
The syntheses of four D-myo-inositol 1,4,5-trisphosphate (InsP3) derivatives, incorporating phosphate bioisosteres at the 5-position, are reported. methyl ester and sulfate derivatives retain InsP3receptor (InsP3R) agonist activity; compounds that possess a methylphosphonate or carboxymethyl moiety InsP3R antagonists.
AbstractThe introduction of food wastes into anaerobic digestion (AD) brings a promising scenario increasing feedstock availability and overall energy production from AD. This study evaluated the biodegradability methane potential co-digestion two typical wastes, kitchen waste chicken fat, with dairy manure. For single substrate, bio-methane assays showed that had highest yield 352 L-CH4 kg–1-VS added, 92% more than manure alone. Chicken fat at same Volatile Solid (VS) level (2 g L–1)...