Robert Moonsamy Gengan

ORCID: 0000-0003-1643-9977
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Synthesis and biological activity
  • Multicomponent Synthesis of Heterocycles
  • Nanoparticles: synthesis and applications
  • Synthesis and Biological Evaluation
  • Moringa oleifera research and applications
  • Ionic liquids properties and applications
  • Nanomaterials for catalytic reactions
  • Synthesis of Organic Compounds
  • Cancer therapeutics and mechanisms
  • Synthesis and bioactivity of alkaloids
  • Mycotoxins in Agriculture and Food
  • Organophosphorus compounds synthesis
  • Advanced Nanomaterials in Catalysis
  • Advanced biosensing and bioanalysis techniques
  • Chemical Synthesis and Reactions
  • Synthesis and Characterization of Heterocyclic Compounds
  • Inorganic and Organometallic Chemistry
  • Quantum Dots Synthesis And Properties
  • Diverse Scientific Research Studies
  • Bioactive natural compounds
  • Metal complexes synthesis and properties
  • Click Chemistry and Applications
  • Cholinesterase and Neurodegenerative Diseases
  • Computational Drug Discovery Methods
  • Electrochemical sensors and biosensors

Durban University of Technology
2015-2024

Anka Teknoloji Üniversitesi
2022

Faculty (United Kingdom)
2015

University of Winnipeg
2010

University of Manitoba
2010

The hazardous effects of current nanoparticle synthesis methods have steered researchers to focus on developing newer eco-friendly for synthesizing nanoparticles using non-toxic chemicals. Owing the diverse applications in various fields such as catalysis, medicine, diagnostics, and sensors, several novel green approaches been explored different natural sources plants, algae, bacteria, fungi. Hence, present work, a method gold (AuNPs) under ambient conditions aqueous extracts marine brown...

10.1007/s40097-015-0173-y article EN cc-by Journal of nanostructure in chemistry 2015-10-23

Abstract Background Silver nanoparticles (AgNP), the most popular nano-compounds, possess unique properties. Albizia adianthifolia (AA) is a plant of Fabaceae family that rich in saponins. The biological properties novel AgNP, synthesized from an aqueous leaf extract AA (AA AgNP ), were investigated on A549 lung cells. Cell viability was determined by MTT assay. Cellular oxidative status (lipid peroxidation and glutathione (GSH) levels), ATP concentration, caspase-3/-7, -8 −9 activities...

10.1186/1477-3155-11-5 article EN cc-by Journal of Nanobiotechnology 2013-02-18

Gold nanoparticles (AuNP's) facilitate cancer cell recognition and can be manufactured by green synthesis using nutrient rich medicinal plants such as Moringa oleifera (MO). Targeting dysregulated oncogenes tumor suppressor genes is crucial for therapeutics. We investigated the antiproliferative effects of AuNP synthesized from MO aqueous leaf extracts (MLAuNP ) in A549 lung SNO oesophageal cells. A one-pot technique was used to synthesise MLAuNP . A549, cells normal peripheral blood...

10.1002/jcb.25528 article EN Journal of Cellular Biochemistry 2016-02-29

This study was aimed at developing a simple, eco-friendly and cost effective green chemistry method for the synthesis of bimetallic Au-Ag nanoparticles using Ocimum basilicum aqueous leaf flower extracts, respectively as natural reducing agents. The successive reduction chloroauric acid silver nitrate led to formation within 10 min room temperature, suggesting higher reaction rate than chemical methods involved in synthesis. Stable, spherical with well-defined dimensions average size 3-25 nm...

10.5185/amlett.2015.5997 article EN Advanced Materials Letters 2015-12-01

Aim: Hepatocellular carcinoma is one of the leading global epidemics. A medicinal tree, Moringa oleifera (MO), has been part traditional treatments including cancer therapies. We investigated apoptosis inducing effects MO crude aqueous leaf extract (MOE) in human liver hepatocellular (HepG2) cells.Methods: HepG2, PBMCs and Hek293 cell viability was evaluated using MTT assay. Oxidative stress DNA damage determined TBARS comet assays, respectively. Apoptosis assessed by caspase-9, -3/7...

10.1080/01635581.2019.1597136 article EN Nutrition and Cancer 2019-04-04

CO2 fixation is thought to be one of the key factors in mitigating global warming. Of various methods for removing CO2, NAD-dependent formate dehydrogenase from Candida boidinii (CbFDH) has been widely used biological CO2-reduction systems; however, practical applications CbFDH have often impeded owing its low CO2-reducing activity. It recently demonstrated that Thiobacillus sp. KNK65MA (TsFDH) a higher activity compared with CbFDH. The crystal structure TsFDH revealed unit asymmetric two...

10.1107/s1399004714025474 article EN Acta Crystallographica Section D Biological Crystallography 2015-01-22

Acetylcholinesterase (AChE) inhibition-directed phytochemical studies on the methanolic extract of Buxus natalensis, collected in South Africa, resulted isolation 12 compounds: O2-natafuranamine (1), O10-natafuranamine (2), cyclonataminol (3), 31-demethylbuxaminol A (4), buxaminol (5), buxafuranamide (6), buxalongifolamidine (7), buxamine (8), cyclobuxophylline K (9), C (10), methyl syringate (11), and p-coumaroylputrescine (12). Compounds 1−4 were new alkaloids, compound 5 was isolated for...

10.1021/np100494u article EN Journal of Natural Products 2010-10-18

The unexpected formation of 5,6-dihydrobenzo[1,7]phenanthroline instead 5,6-dihydrobenzo[1,7]phenanthroline-3-carbonitrile in acridine molecules using Michael addition has been observed for the first time.

10.1039/c4ra16640j article EN RSC Advances 2015-01-01

Antimicrobial resistance is a global health challenge, and the large loads of biocides dumped into environment augment spread antifungal environmental contamination. Therefore, eco‐friendly agents must be developed to combat antibiotic reduce In present investigation, Allium sativum (Hill garlic‐Malai Poondu) extract was used as green resource achieve silver nanoparticle (AgNP) production. AgNPs were characterized by various spectral microscopic analyses. vitro free radical scavenging assays...

10.1155/2022/7613210 article EN cc-by Journal of Nanomaterials 2022-01-01

Important physico-chemical properties of ionic liquids (ILs) can be manipulated by adjusting the nature cation or anion.

10.1039/c6ra11327c article EN RSC Advances 2016-01-01
Coming Soon ...