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Thomas A. Campbell-James

ORCID: 0000-0003-1648-0515
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About
Contact & Profiles
A5001529754
Research Areas
  • Immune cells in cancer
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Histone Deacetylase Inhibitors Research

Ludwig-Maximilians-Universität München
 2020

 Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability
OPENALEX - Publications 
Yaw Asare Thomas A. Campbell-James Yury Bokov Lydia Luya Yu Matthias Prestel and 19 more Omar El Bounkari Stefan Roth Remco T. A. Megens Tobias Straub Kyra Thomas Guangyao Yan Melanie Schneider Natalie Ziesch Steffen Tiedt Carlos Silvestre-Roig Quinte Braster Yishu Huang Manuela Schneider Rainer Malik Christof Haffner Arthur Liesz Oliver Soehnlein Jürgen Bernhagen Martin Dichgans

Arterial inflammation manifested as atherosclerosis is the leading cause of mortality worldwide. Genome-wide association studies have identified a prominent role HDAC (histone deacetylase)-9 in and its clinical complications including stroke myocardial infarction. To determine mechanisms linking HDAC9 to these vascular pathologies explore therapeutic potential for atheroprotection. We studied effects Hdac9 on features plaque vulnerability using bone marrow reconstitution experiments...

10.1161/circresaha.120.316743 article EN Circulation Research 2020-06-17
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