Zhanhong Li

ORCID: 0000-0003-1654-171X
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About
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Research Areas
  • Animal Disease Management and Epidemiology
  • Vector-Borne Animal Diseases
  • Viral Infections and Vectors
  • Genomics and Phylogenetic Studies
  • Microbial infections and disease research
  • Viral Infections and Immunology Research
  • Plant Disease Resistance and Genetics
  • Viral gastroenteritis research and epidemiology
  • Toxoplasma gondii Research Studies
  • Animal Virus Infections Studies
  • Cytomegalovirus and herpesvirus research
  • Herpesvirus Infections and Treatments
  • Bacteriophages and microbial interactions
  • Plant Pathogenic Bacteria Studies
  • Plant-Microbe Interactions and Immunity
  • Microbial Metabolic Engineering and Bioproduction
  • Insect Resistance and Genetics
  • Aluminum toxicity and tolerance in plants and animals
  • Essential Oils and Antimicrobial Activity
  • Legume Nitrogen Fixing Symbiosis
  • GABA and Rice Research
  • Silicon Effects in Agriculture
  • T-cell and Retrovirus Studies
  • Geochemistry and Elemental Analysis

Yunnan Animal Science and Veterinary Institute
2018-2025

Ministry of Agriculture and Rural Affairs
2024-2025

Chinese Academy of Agricultural Sciences
2023

Institute of Plant Protection
2023

China Agricultural University
2014

Bluetongue virus (BTV) is the 'type' species of genus Orbivirus causing bluetongue (BT) in sheep, bovine and other ruminants. Twenty-four serotypes several atypical BTV were identified worldwide. In present study, a novel strain (V196/XJ/2014) was isolated from an asymptomatic sentinel goat Yuli County, Xinjiang China. Serotype identification this isolate exhibited uniform negative results by serotype-specific conventional RT-PCR real-time for BTV-1 to BTV-27, neutralization tests using...

10.1111/tbed.13927 article EN Transboundary and Emerging Diseases 2020-11-15

Abstract Background Some species of Culicoides (Diptera, Ceratopogonidae) are major vectors for arboviruses, and Yunnan Province is a key area arbovirus prevalence in China. Therefore, this study attempts to search potential the common orbiviruses bluetongue virus (BTV), epizootic hemorrhagic disease (EHDV), Palyam (PALV) Tibet orbivirus (TIBOV) Province, Methods specimens were collected from 16 counties China, using UV traps tested BTV, EHDV, PALV TIBOV through one-step reverse...

10.1186/s13071-025-06679-1 article EN cc-by Parasites & Vectors 2025-02-24

In order to investigate the causes of swine diarrhea in Yunnan Province, this study was conducted detect and monitor viruses through regular sampling reverse transcription polymerase chain reaction (RT-PCR). October 2023, porcine sapelovirus (PSV) detected fecal specimens collected from diarrheal pigs Honghe City, three strains PSV were successfully isolated by inoculating them into PK-15 cells; electron microscopy revealed virus particles with diameters ~32 nm. Next-generation sequencing...

10.3390/v17040505 article EN cc-by Viruses 2025-03-31

Bacterial fruit blotch (BFB), caused by Acidovorax citrulli, severely damages watermelon, melon, and other cucurbit crops worldwide. Nitrogen, one of the most important limiting elements in environment, is necessary for growth reproduction bacteria. As a nitrogen-regulating gene, ntrC plays an role maintaining bacterial nitrogen utilization biological fixation. However, has not been determined A. citrulli. In this study, we constructed deletion mutant corresponding complementary strain...

10.3390/microorganisms11030767 article EN cc-by Microorganisms 2023-03-16

Epizootic hemorrhagic disease virus (EHDV) is a member of the genus Orbivirus, family Sedoreoviridae. It was firstly recognized in 1955 to cause highly fatal wild white-tailed deer America. So far, EHDV detected and isolated many or domestic ruminants, widely distributed all over world. Although cattle sheep infected by were usually asymptomatic subclinical, several outbreaks epizootic (EHD) had been reported. Many strains sequenced last two decades China, which promoted general serologic...

10.1016/j.virs.2022.06.005 article EN cc-by-nc-nd Virologica Sinica 2022-06-17

Bluetongue is an arthropod-borne viral disease of ruminants caused by bluetongue virus (BTV). In China, BTV relatively common in Yunnan Province with the exception northern regions around Shangri-La, where average altitude approximately 3,450 metres. Recently, seroprevalence has been measured yaks Shangri-La; therefore, this study investigated infections area. The serological investigation five villages Shangri-La showed that there were sporadic (20 507 positive) during 2014 to 2017, while...

10.1111/tbed.13292 article EN cc-by Transboundary and Emerging Diseases 2019-07-12

Enterovirus G (EV-G) is prevalent in pig populations worldwide, and a total of 20 genotypes (G1 to G20) have been confirmed. Recently, recombinant EV-Gs carrying the papain-like cysteine protease (PLCP) gene porcine torovirus isolated or detected, while their pathogenicity poorly understood. In this study, an EV-G17-PLCP strain, 'EV-G/YN23/2022', was from feces pigs with diarrhea, virus replicated robustly numerous cell lines. The isolate showed highest complete genome nucleotide (87.5%)...

10.3390/v15081747 article EN cc-by Viruses 2023-08-15

A novel Gram-stain-negative, aerobic, coccus-shaped bacteria, designated ZY201115 T , was isolated from the nasal cavity of a sheep with respiratory disease in Yunnan Province, south-west China, and its taxonomic affiliation studied by applying polyphasic approach. The strain grew at 18–41 °C (optimum, 37 °C), pH 6.0–9.0 8.0) 0.5–3.0% (w/v) NaCl 1.0 % NaCl). Phylogenetic analysis based on 16S rRNA gene sequences showed that is affiliated to genus Moraxella highest similarity bovis ATCC 10900...

10.1099/ijsem.0.005511 article EN INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY 2022-09-06

Abstract Background Hemorrhagic varicella (HV) is a particular form of chicken pox.,with high mortality in adults. This the disease rare, to date, approximately 4 cases have been reported. Occasional HV documented adults with hematologic disorders or other diseases. While there one reported case simultaneous reactivation cytomegalovirus an adult chickenpox, lack information regarding changes liver function indicators for such patients. unfortunate, as CMV can further exacerbate failure and...

10.1186/s12879-024-09383-0 article EN cc-by BMC Infectious Diseases 2024-07-11

Culicoides spp. (Diptera: Ceratopogonidae) are small biting midges, some of which the vectors arboviruses affecting livestock, i.e. , African horse sickness virus (AHSV), bluetongue (BTV), and epizootic hemorrhagic disease (EHDV). Yunnan Province, located in southwestern China, has a history high prevalence arboviruses. The diversity abundance was observed between March 2022 2023 on two cattle farms Lufeng County China isolation PCR detection were attempted from blood collected farms. Light...

10.1051/parasite/2024072 article EN cc-by Parasite 2024-01-01

Tibet orbivirus (TIBOV), a new candidate of Orbivirus genus, was initially isolated from mosquitoes in 2009 and subsequently both Culicoides several provinces China Japan. Little is known about the origin, genetic diversity, dissemination pathogenicity TIBOV, although its potential threat to animal health has been acknowledged. In this study, two viruses, V290/YNSZ V298/YNJH, were sentinel cattle Yunnan Province. Their genome sequences, cell tropism mammalian insect lines along with suckling...

10.1111/tbed.14691 article EN Transboundary and Emerging Diseases 2022-09-01

bluetongue virus (BTV) infection triggers dramatic and complex changes in the host's transcriptional profile to favor its own survival reproduction. However, there is no whole-transcriptome study of susceptible animal cells with BTV infection, which impedes in-depth systematical understanding comprehensive characterization BTV-host interactome, as well pathogenic mechanisms. systematically understand these changes, we performed sequencing serotype 1 (BTV-1)-infected mock-infected sheep...

10.3389/fimmu.2022.1053059 article EN cc-by Frontiers in Immunology 2022-12-01

Enterovirus G (EV-G) belongs to the Picornaviridae family and infects porcine populations worldwide. A total of 20 EV-G genotypes (EV-G1 EV-G20) have been identified. In this study, we isolated characterized an strain, named EV-G/YN29/2022, from feces diarrheic pigs. This was first EV-G6 strain in China. Comparison whole genome nucleotide corresponding amino acid sequences showed that isolate more closely related those genotype than other genotypes, with complete sequence similarity ranging...

10.3389/fvets.2024.1431180 article EN cc-by Frontiers in Veterinary Science 2024-07-24

The full-genome sequence of bluetongue virus serotype 15 (BTV-15) strain B105/YN/1996 isolated in China was determined for the first time. from sentinel cattle Yunnan Province, China, 1996. total size BTV-15 genome is 19,161 bp length. Phylogenetic analyses demonstrate that it belongs to major eastern BTV topotype. This work document complete genomic a China. information will help determine geographic origin Chinese and provide data facilitate future genetic diversity phylogenetic...

10.1128/genomea.00557-18 article EN Genome Announcements 2018-06-27
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