A5030224914- SARS-CoV-2 and COVID-19 Research
- Computational Drug Discovery Methods
- Genomics and Phylogenetic Studies
- Ginger and Zingiberaceae research
- Pharmacological Effects of Natural Compounds
- COVID-19 Clinical Research Studies
- Vitamin C and Antioxidants Research
- Diphtheria, Corynebacterium, and Tetanus
- Advanced biosensing and bioanalysis techniques
- Piperaceae Chemical and Biological Studies
- Natural Antidiabetic Agents Studies
- Hepatitis B Virus Studies
- Moringa oleifera research and applications
- Cholesterol and Lipid Metabolism
- COVID-19 diagnosis using AI
- Phytochemicals and Antioxidant Activities
- Viral Infections and Immunology Research
- vaccines and immunoinformatics approaches
- PI3K/AKT/mTOR signaling in cancer
- Plant Gene Expression Analysis
- Artificial Intelligence in Healthcare and Education
- Machine Learning in Bioinformatics
- Bioactive Compounds and Antitumor Agents
- Diverse Scientific Research Studies
- Enterobacteriaceae and Cronobacter Research
Siksha O Anusandhan University
2020-2025
Central Inland Fisheries Research Institute
2024-2025
Indian Institute of Horticultural Research
2024
Odisha University of Agriculture and Technology
2016-2024
Institute of Medical Sciences and Sum Hospital
2024
Bridge University
2021
Bhavnagar University
2021
Abstract The Sundarbans, the world’s largest tidal mangrove forest, acts as a crucial ecosystem for production, conservation, and cycling of carbon nitrogen. study explored hypothesis that microbial communities in ecosystems exhibit unique taxonomic functional traits play vital part resilience. Using metagenomic analysis to evaluate non-mangrove environment, evaluating their composition, functions, ecological relevance. revealed distinct profiles, environments, with bacteria, proteobacteria,...
The new severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) is the etiological agent of Coronavirus disease 2019 (COVID-19), which becomes an eventual pandemic outbreak. Lack proper therapeutic management has accelerated researchers to repurpose existing drugs with known preclinical and toxicity profiles, can easily enter Phase 3 or 4 be used directly in clinical settings. Vitamins are necessary nutrients for cell growth, function, development. Furthermore, they play important role...
The present research deals with studying the phytoconstituents, antioxidant potential, cytotoxicity and anti-inflammatory activities of Zingiber zerumbet rhizome essential oil (ZZEO). A total 29 components were identified using GC-MS accounting for 94.68% EO composition. ZZEO was characterized by sesquiterpenes, comprising 83.11% composition zerumbone (68.18%) α-Humulene (11.72%) as major compounds. DPPH FRAP assays showed IC50 values 83.90±0.05 mg/ml 1.98±0.04 respectively. in silico PASS...
Labeo calbasu ( L. ) is an important detrivore fish in ecosystem. So, the present transcriptome study was undertaken relation to polluted and non-polluted water sources from a natural perennial river system. The Illumina NovaSeq 6000 platform used perform analysis on liver samples of that were collected Ganga Yamuna rivers. From 8744 differentially expressed genes (DEGs), 2538 upregulated, 6206 downregulated response pollution stress. Biologic process (BP), cellular component (CC), molecular...
Inflammation is caused by a cascade of events, one which the metabolism arachidonic acid, that begins with oxidation enzyme 5-lipoxygenase. 5-Lipoxygenase (5-LOX) plays an important role in inflammation process synthesizing leukotrienes and several lipid mediators has emerged as possible therapeutic target for treatment inflammatory diseases such asthma rheumatoid arthritis. Most existing 5-LOX inhibitors are synthetic exhibit adverse side effects. In view this, there need to search...
is an essential oil bearing plant extensively used in the traditional system of medicine several countries. Previous research has revealed
The essential oil (EO) derived from Curcuma angustifolia Roxb. has gained significant interest in traditional medicine, specifically for its potential as a therapeutic agent inflammatory disorders. Our study aimed to identify the chemical constituents of C. EO, investigate anti-inflammatory effects lipopolysaccharide (LPS)-treated RAW 264.7 cells and explore nitric oxide (NO) inhibitors through silico based studies. obtained hydro-distillation underwent analysis via gas chromatography-mass...
Cyclooxygenase 2 (COX-2), the key enzyme involved in prostaglandin (PGs) production, is known to take part inflammatory and immune responses. Though COX-2 inhibitors are therapeutically effective anti-inflammatory drugs, they deficit anti-thrombotic activity thus leading increased cardiovascular diseases. Therefore, with improved therapeutic efficacy tolerance still needed. In recent years, traditional medicine systems have paid attention essential oil of genus Zingiber, particularly for...
NAM, ATAF, and CUC (NAC) transcription factors comprise a large plant-specific gene family few members of this have been characterized for their roles in plant growth, development, stress tolerance. Although recent genome sequencing Capsicum annum aid identification NAC but which is yet to be complete terms other capsicum species. So the present work was undertaken screen identify from two sequences i.e., ang Zunla Chileptein through comparative genomics approach using known Solanaceae...
Abstract The emergence situation of coronavirus disease 2019 (COVID-19) pandemic has realised the global scientific communities to develop strategies for immediate priorities and long-term approaches utilization existing knowledge resources which can be diverted preparedness planning. Lack proper vaccine candidate therapeutic management accelerated researchers repurpose drugs with known preclinical toxicity profiles, easily enter Phase 3 or 4 used directly in clinical settings. We focused...
Abstract Furin, a pro-protein convertase, plays significant role of biological scissor in bacterial, viral, and even mammalian substrates which turn decides the fate many viral bacterial infections along with numerous ailments caused by cancer, diabetes, inflammations, neurological disorders. In wake current pandemic virus SARS COV-2, furin has become center attraction for researchers. present work, we have searched novel inhibitors against this interesting human target from FDA-approved...
Pointed gourd (Trichosanthes dioica Roxb) is a perennial cucurbitaceous vegetable popular in the eastern and northern parts of India. In July 2018, an occurrence southern blight disease was observed pointed crop grown Odisha state located part The typical symptoms included angular necrotic patches disintegration leaf tissues with vein veinlet intact, exhibiting diagnostic netted pattern veins. Silky white, fan-shaped mycelial growth sclerotial bodies on lower surface infected leaves....