A5013413764- Sperm and Testicular Function
- Reproductive Biology and Fertility
- Sexual Differentiation and Disorders
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Bladder and Urothelial Cancer Treatments
- Prostate Cancer Treatment and Research
- Prostate Cancer Diagnosis and Treatment
- Hormonal and reproductive studies
- Reproductive Health and Technologies
- Urinary and Genital Oncology Studies
- Pediatric Urology and Nephrology Studies
- Sexual function and dysfunction studies
- Testicular diseases and treatments
- Kidney Stones and Urolithiasis Treatments
- Urologic and reproductive health conditions
- Genital Health and Disease
- Renal cell carcinoma treatment
- Pelvic floor disorders treatments
- Metabolism and Genetic Disorders
- Advanced Breast Cancer Therapies
- Urological Disorders and Treatments
- Esophageal Cancer Research and Treatment
- Urinary Bladder and Prostate Research
- Ureteral procedures and complications
- Ovarian function and disorders
National Yang Ming Chiao Tung University
2015-2024
Taipei Veterans General Hospital
2015-2024
Northwestern University
1977-2020
National Taipei University
2018-2020
Sichuan Agricultural University
2020
Taipei City University of Science and Technology
2020
University of Chicago
2020
GTx (United States)
2020
Taipei Institute of Pathology
2019
ORCID
2019
Abstract To evaluate the performance of Prostate Health Index (PHI) in magnetic resonance imaging-transrectal ultrasound (MRI-TRUS) fusion prostate biopsy for detection clinically significant cancer (csPCa). We prospectively enrolled 164 patients with at least one Imaging Reporting and Data System version 2 (PI-RADS v2) ≥ 3 lesions who underwent MRI-TRUS biopsy. Of PSA-derived biomarkers, PHI had best predicting csPCa (AUC 0.792, CI 0.707–0.877) PI-RADS 4/5 lesions. Furthermore, predictive...
An accurate diagnosis of the etiology azoospermia is crucial, as sperm retrieval methods differ between patients with non-obstructive (NOA) and obstructive (OA). The aim this study was to determine hormone testes size cutoff values identify cause in Taiwanese patients.The medical records azoospermic were retrospectively collected from April 2008 July 2016, including profile, physical examination findings, size. Bilateral biopsies or microdissection testicular extraction performed all for a...
The lip gene of Escherichia coli has been cloned and sequenced. Subcloning a 3-kilobase EcoRI/EcoRV restriction fragment from Clark-Carbon plasmid pLC15-5 into pUC18 gives that complements two lipoate auxotrophs, W1485-lip2 JRG33-lip9, which expresses protein approximately 36,000 Da. Sequencing suggests codes for 281 amino acids (31,350 Da), showing sequence similarity to biotin synthase. It is thus likely encodes sulfur insertion enzyme analogous synthase the chemistries systems are...
Data have been presented confirming experimental production of phenylketonuria in rats. Supplementation the diet with both phenylalanine and tyrosine resulted a marked increase phenylpyruvate excretion urine level plasma. 2.5% DL-phenylalanine alone showed much less effect. The rise coincided decrease 5-hydroxyindole-acetic acid urine. Similarly, plasma 5-hydroxytrypta-mine This indicates that disturbance 5-hydroxyindole metabolism is secondary to phenylalanine. possible significance these...
The primary microenvironment of the testis comprises testicular interstitial fluid (TIF) surrounding seminiferous tubules and tissue. pathological alterations germ Sertoli cells could affect TIF composition might contain putative biomarkers for monitoring active spermatogenesis.
Background: Bacillus Calmette–Guérin (BCG) has been well recognized as the first-line intravesical therapy for high-risk non-muscle-invasive bladder cancer (NMIBC). Oncotice, Tice strain of BCG, serves a viable alternative to Connaught owing worldwide shortage latter. We retrospectively compared these two strains in terms efficacy and adverse effects (AE) patients who underwent at least one maintenance course after induction. Methods: In this single-institution, retrospective study,...
In patients undergoing radical prostatectomy (RP) for prostate cancer (PCa), preoperative prediction of extraprostatic extension (EPE) can facilitate patient selection nerve-sparing procedures. Since both multiparametric magnetic resonance imaging (mpMRI) and health index (PHI) have shown promise the diagnosis prognostication PCa, we investigated whether a combination mpMRI PHI evaluations improve EPE after RP.Patients diagnosed with PCa treated RP were prospectively enrolled between...
The study aimed to comprehensively analyze testosterone and precursor concentrations in the testicular interstitial fluid (TIF) of men with azoospermia, exploring their significance microenvironment correlation sperm retrieval outcomes.
Priapism is a prolonged and persistent erection that lasts more than 4 hours unrelated to sexual stimulation. Although uncommon, it requires expeditious treatment prevent erectile function compromise. Corporal aspiration the first-line for patients with ischemic priapism. This article focuses on contemporary corporal techniques management of After obtaining informed consent administering local anesthesia, was initiated by inserting 2 large-bore butterfly needles into penile shaft. Aspiration...
There are models to predict pathological outcomes based on established clinical and prostate-specific antigen (PSA)-derived parameters; however, they not satisfactory. p2PSA its derived biomarkers have shown promise for the diagnosis prognosis of prostate cancer (PCa). The aim this study was investigate whether p2PSA-derived can assist in prediction aggressive after radical prostatectomy (RP).We prospectively enrolled patients who were diagnosed with PCa treated RP between February 2017...
Abstract Background The purpose of this study is to evaluate the prognostic factors for sperm retrieval and determine if Y chromosome deletion associated with deleterious effects on spermatogenesis in non-mosaic Klinefelter patients. Whether determines rate patients has not yet been addressed. Methods We retrospectively collected medical records azoospermic from Sep 2009 Dec 2018, enrolled 66 47, XXY who were receiving mTESE. predictive values age, serum follicle-stimulating hormone (FSH),...
The management of urolithiasis in the kidney has been drastically changed era endourology, mainly consisting three surgical procedures: extracorporeal shock wave lithotripsy (ESWL), percutaneous nephrolithotomy (PCNL), and retrograde intrarenal surgery (RIRS). Since ESWL is usually less invasive via ambulatory clinic routes, this study aimed to examine stone-free rate (SFR) between PCNL RIRS.We retrospectively reviewed patients who had renal stones were treated with either or RIRS from June...
Abstract A practical synthetic method for the title disaccharide 2 is described. Glycosylation using thioglycoside as acceptor and glycosyl imidate donor was performed with trimethylsilyltriflate promoter.