A5043254498- Genetic and phenotypic traits in livestock
- Milk Quality and Mastitis in Dairy Cows
- Reproductive Physiology in Livestock
- Ruminant Nutrition and Digestive Physiology
- Effects of Environmental Stressors on Livestock
- Animal Behavior and Welfare Studies
- Genetic Mapping and Diversity in Plants and Animals
- Animal Genetics and Reproduction
- Probiotics and Fermented Foods
- Animal Disease Management and Epidemiology
- Microbial infections and disease research
- Electric Motor Design and Analysis
- Animal Nutrition and Physiology
- Meat and Animal Product Quality
- Reproductive Health and Technologies
- Neurogenesis and neuroplasticity mechanisms
- Infant Nutrition and Health
- Livestock Management and Performance Improvement
- Immune Response and Inflammation
- Epigenetics and DNA Methylation
- Sperm and Testicular Function
- Advanced DC-DC Converters
- Dyeing and Modifying Textile Fibers
- Neuroinflammation and Neurodegeneration Mechanisms
- Reproductive Biology and Fertility
Decipher Biosciences (Canada)
2021-2023
Echelon Biosciences
2023
St. Luke's Hospital
2019
University of Utah
2017-2018
Roche (United States)
2018
Brigham Young University
2014
Agricultural Research Service
2000-2012
Beltsville Agricultural Research Center
1998-2012
The Open University
2005
Los Alamos National Laboratory
2005
The HNK-1 and L2 monoclonal antibodies are thought to recognize identical or closely associated carbohydrate epitopes on a family of neural plasma membrane glycoproteins, including myelin-associated glycoprotein, the cell adhesion molecule, L1 J1 all which have been postulated play part in mediating cell-cell interactions nervous system. We used these two immunofluorescence immunogold-electron microscopic studies semithin ultrathin frozen sections adult rat optic nerve, respectively, we show...
Metastatic breast cancer remains challenging to treat, and most patients ultimately progress on therapy. This acquired drug resistance is largely due drug-refractory sub-populations (subclones) within heterogeneous tumors. Here, we track the genetic phenotypic subclonal evolution of four cancers through years treatment better understand how become drug-resistant. Recurrently appearing post-chemotherapy mutations are rare. However, bulk single-cell RNA sequencing reveal acquisition malignant...
The organization of intermediate filaments in cultured epithelial cells was rapidly and radically affected by intracellularly injected monoclonal antikeratin filament antibodies. Different antibodies had different effects, ranging from an apparent splaying apart keratin bundles to the complete disruption network. Antibodies were detectable within for more than four days after injection. antibody-induced no light-microscopically discernible effect on microfilament or microtubule organization,...
SummaryA mammary quarter in each of 4 cows was infused with 0.5 mg E. coli endotoxin to determine its effect on plasma corticosteroids, circulating leukocytes and milk somatic cells. At 1.5 hr following infusion, segmented neutrophils decreased 23%, by 5 dropped 93%. A shift left the differential leukocyte count began at 2.5 reached maximum proportions between 18-24 postendotoxin infusion. Circulating lymphocytes, monocytes eosinophils were all depressed response endotoxin. Plasma...
Michigan DHIA-IBM records for 4,677 Holsteins~ 1,001 Guernseys, and 501 Jerseys were used to fit constants by least squares the independent influences of age weight on production in first lactation.These effects indicated that delaying calving heifers is economically disadvantageous heavier have little or no advantage over lighter similar age.Intraherd partial regressions about 75 lb. milk per month 200 100 lb.weight at calving.Large correlation between herd averages contributed...
Quantitative trait loci (QTL) affecting health and milk production traits were studied in seven large half‐sib US Holstein families by using the granddaughter design. Genotyping for 16 markers was completed marker allele differences within pooled‐across analysed. Potential QTL identified somatic cell score (SCS), fat yield, percentage, protein yield percentage. Three (BM203, BM4505 BM2078) associated with significant effects different and, after further analysis, may be useful...
(1983). Relationships of Milk Somatic Cell Counts to Daily Yield and Composition. Acta Agriculturae Scandinavica: Vol. 33, No. 3, pp. 209-223.
Polygenic scores (or genetic risk scores) quantify the aggregate of small effects from many common loci that have been associated with a trait through genome-wide association. were first used successfully in schizophrenia and since applied to multiple phenotypes including sclerosis, rheumatoid arthritis, height. Because human height is an easily-measured complex polygenic trait, provide exciting insights into predictability variant effect on phenotype. Shawn Bradley extremely tall former...
DATA on body weights at birth, 21, 56, 98 and 140 days, average daily gain from 56 days to a live weight of about 79.4 kg required reach were analyzed evaluate the correlated responses these traits selection for high low backfat thickness in two lines Durocs Yorkshires. Based data collected through 13 11 generations selection, respectively, given by both pre- postweaning growth measures differed rather markedly between Duroc Yorkshire lines. In each five studied gave evidence being...