A5035987120- Allergic Rhinitis and Sensitization
- Venous Thromboembolism Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- Asthma and respiratory diseases
- Respiratory and Cough-Related Research
- Sinusitis and nasal conditions
- Olfactory and Sensory Function Studies
- Nasal Surgery and Airway Studies
- Antiplatelet Therapy and Cardiovascular Diseases
- Intracerebral and Subarachnoid Hemorrhage Research
- Pharmacological Effects and Toxicity Studies
- Pharmacovigilance and Adverse Drug Reactions
- Dermatology and Skin Diseases
- Diet, Metabolism, and Disease
- Liver Disease and Transplantation
- Medical and Pharmaceutic Studies
- Pain Management and Opioid Use
- Liver Disease Diagnosis and Treatment
- Epilepsy research and treatment
- Neurological and metabolic disorders
- Economic, Social, and Public Health Issues in Russia and Globally
- Heparin-Induced Thrombocytopenia and Thrombosis
- Pediatric Pain Management Techniques
Sanofi (United States)
2022
Sanofi (France)
2022
Volgograd State Medical University
2013-2017
Ministry of Health of the Russian Federation
2016
<b><i>Introduction:</i></b> Allergic rhinitis (AR) is a disease that affects ≤24% of people in Russia, significantly impairing quality life (QoL). Intranasal corticosteroids, such as triamcinolone acetonide (TAA), are considered effective drugs for treatment. A post hoc analysis data (phase III NASANIF trial) examined weekly QoL changes patients receiving TAA the treatment perennial AR (PAR). <b><i>Methods:</i></b> (NCT03317015) was...
Aim. To assess prescribing structure, efficacy and safety of antithrombotic therapy in in-patients with permanent atrial fibrillation (AF). Material methods. Simple non-comparative retrospective descriptive one stage pharmacoepidemiological study was performed on the basis analysis 263 case histories patients AF admitted to cardiology department a general hospital. Results. All were stratified into three groups depending value index CHA2DS2-VASc. Antithrombotic evaluated each group. 1% (n=3)...
Aim. Analysis of the efficacy and safety new oral anticoagulants (NOACs) in management venous thromboembolism (VTE). Material methods. This meta-analysis randomized controlled trials (RCTs) was made accordance with instructions "Preferred reporting items for systematic reviews meta-analyses (PRISMA)". Results. The included 5 RCTs. NOACs were as effective vitamin K antagonists (VKAs) preventing recurrent symptomatic VTE (RR=0.93; 95% CI 0.77-1.12; p=0.44). incidence thrombosis (RR=0.82;...
<b><i>Introduction:</i></b> Allergic rhinitis (AR) is a disease which affects &#x3e;24% of the population in Russia. Triamcinolone acetonide (TAA) corticosteroid used for treating AR. This post hoc analysis assesses efficacy intranasal TAA improving perennial AR (PAR) symptom scores over 4 weeks. <b><i>Methods:</i></b> NASANIF (NCT03317015) was double-blind, parallel-group, multicenter, prospective, non-inferiority, phase III clinical trial...
Aim. To evaluate the prevalence of accomplished goal in laboratory clotting parameters for anticoagulant therapy deep vein thrombosis (DVT). Material and methods. The study is performed as one-stage, descriptive, analytic, pharmacoepidemiologic investigation. material were 200 case histories DVT from Volgograd hospitals. analyzed were: structure prescription, coagulogrammes with APTT, prothrombin complex INR. Results. Direct acting anticoagulants prescribed 91% cases. High-molecular heparin...
Aim. To analyze adverse drug reactions (ADR) during antithrombotic therapy on the basis of spontaneous reports registered in Volgograd city and region 2010-2012. Material methods. It was analytical retrospective pharmacoepidemiological study. ADR submitted to Regional Centre for Drug Safety Monitoring were used. Results. Regarding drugs 18 suspected or ineffectiveness (from 562). Most accounted by indirect- acting anticoagulating agents — 66.7% (12/18), direct-acting anticoagulants 22.2%...
Objective. The aim was to perform an indirect comparisons of the effectiveness and safety new oral anticoagulants (NOACs) in management venous thromboembolism (VTE). Material methods. In absence a head-to-head comparisons, comparison done using method proposed by Butcher et al. Results. included 5 RCTs. Apixaban, rivaroxaban dabigatran were equally effective preventing recurrent symptomatic VTE, deep vein thrombosis pulmonary embolism. Dabigatran increased major bleeding risk compared...
ФАРМАКОЭКОНОМИЧЕСКИЙ АНАЛИЗ ПРИМЕНЕНИЯ НОВЫХ ПЕРОРАЛЬНЫХ АНТИКОАГУЛЯНТОВ ПРИ ВЕНОЗНЫХ ТРОМБОЭМБОЛИЧЕСКИХ ОСЛОЖНЕНИЯХ О. В
This study was sponsored by Sanofi. Allergic rhinitis impairs the Quality of Life (QoL) and affects ∼24% population in Russia. The purpose this post-hoc analysis to estimate QoL improvement over weeks treatment with triamcinolone acetonide (TAA) or fluticasone propionate (FP). A randomized, double-blind, parallel-group, multicenter, phase III non-inferiority clinical trial conducted (NCT 03317015) patients PAR, treated either TAA (220 μg/day) FP (200 for 28 days. assessed applying mini...
Allergic rhinitis is a common problem with increasing prevalence. Two recent publications demonstrate that intranasal triamcinolone acetonide an effective treatment progressively improves nasal symptoms and quality of life in adult patients perennial allergic rhinitis.
Die allergische Rhinitis ist ein häufiges Problem mit steigender Prävalenz. Zwei aktuelle Publikationen zeigen, dass intranasal verabreichtes Triamcinolonacetonid wirksam und zunehmend nasale Symptome die Lebensqualität von Patienten ganzjähriger allergischer verbessert.
La rinitis alérgica es un problema común con una prevalencia creciente. Dos publicaciones recientes demuestran que la triamcinolona acetónido intranasal fármaco eficaz mejora progresivamente los síntomas nasales y calidad de vida en pacientes adultos perenne.
Аллергический ринит является распространенной проблемой, частота случаев которой всё время растет. В двух недавних публикациях было показано, что интраназальный триамцинолона ацетонид эффективным средством, которое неуклонно облегчает назальные симптомы и улучшает качество жизни взрослых пациентов с круглогодичным аллергическим ринитом.
La rinite allergica è un problema comune, la cui prevalenza in aumento. Due recenti pubblicazioni dimostrano che il triamcinolone acetonide per uso intranasale trattamento efficace migliora progressivamente i sintomi nasali e qualità della vita dei pazienti adulti con perenne.
A rinite alérgica é um problema comum que apresenta uma prevalência crescente. Duas publicações recentes evidenciam o acetonido de triancinolona intranasal tratamento eficaz melhora progressivamente os sintomas nasais e a qualidade vida em pacientes adultos com perene.
Η αλλεργική ρινίτιδα είναι ένα συχνό πρόβλημα με αυξανόμενο επιπολασμό. Δύο πρόσφατες δημοσιεύσεις καταδεικνύουν ότι το ενδορρινικό ακετονίδιο τριαμσινολόνης μια αποτελεσματική θεραπεία που σταδιακά βελτιώνει τα ρινικά συμπτώματα και την ποιότητα ζωής σε ενήλικες ασθενείς ολοετή ρινίτιδα.