A5031345903- Eating Disorders and Behaviors
- Health disparities and outcomes
- COVID-19 and Mental Health
- Mental Health Research Topics
- Obesity and Health Practices
- Empathy and Medical Education
- Health, Environment, Cognitive Aging
- Creativity in Education and Neuroscience
- Emotional Intelligence and Performance
- Body Image and Dysmorphia Studies
- Obsessive-Compulsive Spectrum Disorders
- Consumer Perception and Purchasing Behavior
- Epigenetics and DNA Methylation
- Functional Brain Connectivity Studies
- Child Nutrition and Feeding Issues
- Psychological Well-being and Life Satisfaction
- Religion, Spirituality, and Psychology
- Nutrition, Genetics, and Disease
- Genetic Associations and Epidemiology
- Bipolar Disorder and Treatment
- Sensory Analysis and Statistical Methods
- Health and Wellbeing Research
- Attachment and Relationship Dynamics
- Suicide and Self-Harm Studies
- Cultural Differences and Values
King's College London
2022-2025
South London and Maudsley NHS Foundation Trust
2022-2025
NIHR Maudsley Dementia Biomedical Research Unit
2022-2023
National Institute for Health Research
2022-2023
Maudsley Hospital
2022-2023
Psychiatry Research Trust
2023
NIHR Maudsley Biomedical Research Centre
2022
Wesleyan University
2020
Abstract Depression is a risk factor for the later development of Alzheimer’s disease (AD), but evidence genetic relationship mixed. Assessing depression symptom-specific associations may better clarify this relationship. To address this, we conducted genome-wide meta-analysis (a association study, GWAS) nine symptom items, plus their sum score, on Patient Health Questionnaire (PHQ-9) (GWAS-equivalent N : 224,535–308,421) using data from UK Biobank, GLAD study and PROTECT, identifying 37...
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Objective: This study aimed to identify and categorise under-recognised weight loss behaviours in individuals with eating disorders, addressing diagnostic gaps. Method: We text mined free-text responses from 1,675 participants anorexia nervosa, bulimia or binge-eating disorder the Genetic Links Anxiety Depression (GLAD) Study United Kingdom Eating Disorders Genetics Initiative (EDGI UK). In secondary analyses, we investigated differences by gender. Results: Frequently endorsed included...
Background Eating disorders are severe psychiatric conditions associated with high mortality rates, particularly among young people. These often co-occur self-harm and suicidal ideation, yet the temporal dynamics between these variables remain poorly understood. Aims This study aims to elucidate longitudinal associations eating disorder symptoms, self-harm, ideation using structural equation modelling. Method Repeated measures of phenotypes were used construct a hypothetical model that...
Background: Eating disorders are serious psychiatric associated with high levels of co-occurring physical and mental health conditions, rates relapse poor treatment outcomes. The collection standardised, routinely collected data within clinical services holds promise to improve patient care. Proposals for standardised variables in eating have been made, but not implemented, included limited biological measures. Given emerging evidence about the importance metabolism other factors disorders,...
Background: Eating disorders are serious psychiatric associated with high levels of co-occurring physical and mental health conditions, rates relapse poor treatment outcomes. The collection standardised, routinely collected data within clinical services holds promise to improve patient care. Proposals for standardised variables in eating have been made, but not implemented, included limited biological measures. Given emerging evidence about the importance metabolism other factors disorders,...
Aims: Eating disorders (EDs) are associated with elevated all-cause mortality, suicide cited as the second leading cause of death among individuals EDs. Evidence suggests that anorexia nervosa 18 times, and those bulimia seven times more likely to die by suicide, relative gender- aged-matched comparison groups. Limited research has focused on why people EDs experience such high rates suicidality. The study aims gather perspectives from lived any ED clinicians working understand suicidality...
Abstract Objective The disruption caused by the COVID‐19 pandemic has been associated with poor mental health, including increases in eating disorders and self‐harm symptoms. We investigated risk protective factors for new onset of these symptoms during pandemic. Method Data were from Psychiatry Neurological Genetics study Repeated Assessment Mental health Pandemics Study ( n = 36,715). Exposures socio‐demographic characteristics, lifetime psychiatric disorder, COVID‐related variables,...
The Genetic Links to Anxiety and Depression (GLAD) Study is a large cohort of individuals with lifetime anxiety and/or depression, designed facilitate re-contact participants for mental health research. At the start pandemic, from three cohorts, including GLAD Study, were invited join COVID-19 Psychiatry Neurological Genetics (COPING) study monitor neurological health. However, previous research suggests that participation in longitudinal studies follows systematic, rather than random,...
Abstract Objectives People with bipolar disorder who also report binge eating have increased psychopathology and greater impairment than those without eating. Whether this co‐occurrence is related to as a symptom or presents differently across full‐syndrome disorders unclear. Methods We first compared networks of 13 lifetime mania symptoms in 34,226 participants from the United Kingdom's National Institute for Health Care Research BioResource ( n = 12,104) 22,122) Second, subsample eating,...
Abstract Objective The United Kingdom Eating Disorders Genetics Initiative (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental BioResource, aims to deepen our understanding environmental genetic etiology eating disorders. EDGI UK launched in February 2020 is partnered with disorders charity, Beat. Multiple branches exist worldwide. This article serves dual function providing an in‐depth description study protocol describing initial sample including...
Abstract Background: The Genetic Links to Anxiety and Depression (GLAD) Study is a large cohort of individuals with lifetime anxiety and/or depression, designed facilitate re-contact participants for mental health research. At the start pandemic, from three cohorts, including GLAD Study, were invited join COVID-19 Psychiatry Neurological Genetics (COPING) study monitor neurological health. However, previous research suggests that participation in longitudinal studies follows systematic,...
Abstract Previous research suggests that empathy can be cultivated by social ideals and relationships with people. The current study examines family importance religious as correlates of affective empathy, perspective taking, generativity among a sample adults aged 18 to 35 ( N = 722). Given the ethnic racial diversity represented Millennials Generation Z, moderating role group membership is explored well. Results indicate positively associated for overall sample, though relationship...
Objective: The disruption caused by the COVID-19 pandemic has been associated with poor mental health, including increases in eating disorder and self-harm symptoms. We investigated risk protective factors for new onset of these symptoms during pandemic. Method: Data were from Psychiatry Neurological Genetics study Repeated Assessment Mental health Pandemics Study (n = 45,058). Exposures socio-demographic characteristics, lifetime psychiatric disorder, COVID-related variables, SARS-CoV-2...
Abstract Objective The Eating Disorders Genetics Initiative United Kingdom (EDGI UK), part of the National Institute for Health and Care Research (NIHR) Mental BioResource, aims to deepen our understanding environmental genetic aetiology eating disorders. EDGI UK launched in February 2020 is partnered with disorders charity, Beat. There are multiple branches worldwide. Method recruits via media clinical services. Anyone living England, at least 16 years old, a lifetime probable or disorder...
Objective: The disruption caused by the COVID-19 pandemic has been associated with poor mental health, including increases in eating disorder and self-harm symptoms. We investigated risk protective factors for new onset of these symptoms during pandemic. Method: Data were from Psychiatry Neurological Genetics study Repeated Assessment Mental health Pandemics Study (n = 45,058). Exposures socio-demographic characteristics, lifetime psychiatric disorder, COVID-related variables, SARS-CoV-2...