Vladlena Lee

ORCID: 0000-0003-1684-4569
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About
Contact & Profiles
Research Areas
  • Neural dynamics and brain function
  • Receptor Mechanisms and Signaling
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroblastoma Research and Treatments
  • Traumatic Brain Injury and Neurovascular Disturbances
  • Tracheal and airway disorders
  • Traumatic Brain Injury Research
  • Reconstructive Facial Surgery Techniques

SUNY Downstate Health Sciences University
2022

Cornell University
2019-2022

Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disorder caused by repetitive trauma to the central nervous system (CNS) suffered soldiers, contact sport athletes, and civilians following accident-related trauma. CTE CNS tauopathy, with trauma-induced inflammation leading accumulation of hyperphosphorylated forms microtubule-binding protein Tau (pTau), resulting in neurofibrillary tangles loss neurons. At present, there are no therapies treat CTE. We hypothesized...

10.1089/hum.2019.174 article EN Human Gene Therapy 2019-10-14

SUMMARY Survival requires both the ability to persistently pursue goals and determine when it is time stop, an adaptive balance of perseverance disengagement. Neural activity in lateral habenula (LHb) has been linked aversion negative valence, but its role regulating between reward-seeking disengaged behavioral states remains unclear. Here, we show that LHb neural tonically elevated during minutes-long disengagements from behavior, whether due repeated reward omission or following sufficient...

10.1101/2021.01.15.426914 preprint EN cc-by bioRxiv (Cold Spring Harbor Laboratory) 2021-01-16

Purpose: After 3 weeks of age, studies show ear molding to be unsuccessful due increased regression rates. Studies have not differentiated success rates based on severity; partial regressions may deemed successful and satisfactory by parents. We examined at different ages presentation measuring severity parental satisfaction. Methods: Patients who presented clinic for from January 2017 October 2018 were eligible inclusion. Molds applied the initial visit monitored biweekly. Treatment length...

10.1097/01.gox.0000843116.83598.fa article EN cc-by-nc-nd Plastic & Reconstructive Surgery Global Open 2022-06-01
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