A5051263082- Pediatric Pain Management Techniques
- Musculoskeletal pain and rehabilitation
- Endometriosis Research and Treatment
- Infant Development and Preterm Care
- Pain Mechanisms and Treatments
- Pregnancy-related medical research
- Anesthesia and Pain Management
- Pain Management and Placebo Effect
- Menstrual Health and Disorders
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Childhood Cancer Survivors' Quality of Life
- Migraine and Headache Studies
- Pain Management and Opioid Use
- Pelvic floor disorders treatments
- Myofascial pain diagnosis and treatment
- Family and Disability Support Research
- Hip and Femur Fractures
- Cerebral Palsy and Movement Disorders
- Uterine Myomas and Treatments
- Botulinum Toxin and Related Neurological Disorders
- Perfectionism, Procrastination, Anxiety Studies
- Scoliosis diagnosis and treatment
- Olfactory and Sensory Function Studies
- Hip disorders and treatments
- Sleep and related disorders
Center for Pain and the Brain
2014-2025
Harvard University
2016-2025
Boston Children's Hospital
2016-2025
Massachusetts General Hospital
2024-2025
Boston Children's Museum
2012-2024
Brigham and Women's Hospital
2021
Boston University
2021
Pain and Rehabilitation Medicine
2014-2016
Christie's
2012
University of Rhode Island
2007
Objectives To examine whether protective parent responses mediate the relation between distress and child functioning. Methods At a pain clinic evaluation, 157 families participated. Parents completed measures of global (BSI-18), in context their child’s (BAP-PIQ), to pain. Children functional disability Results BAP-PIQ subscales were significantly associated with disability, whereas BSI unrelated. Protective partially mediated for depression, anxiety, catastrophizing. However, behavior...
Objectives This study compared outcomes between day hospital pain rehabilitation patients and engaged in outpatient multidisciplinary treatment. Methods included 100 children who presented for an initial tertiary care clinic evaluation. 50 enrolled intensive pursued Across 2 time points, completed measures of functional disability, pain-related fear, readiness to change parents fear change. Results both treatment modalities, reported improvements. Patients had significantly larger...
Anxiety is the most common psychiatric condition in children and adolescents, linked to significant disruptions across domains of function. Due avoidant nature anxiety pain-related disability, studying symptoms with chronic recurrent pain conditions important.To examine a large cohort adolescents evaluated for complex conditions.Through retrospective chart review, data on anxiety, functional disability were collected from 655 at multidisciplinary clinic over three-year period.Approximately...
The importance of willingness to adopt a self-management approach chronic pain has been demonstrated in the context cognitive-behaviorally oriented interdisciplinary treatment programs for adults, both as outcome and process that facilitates functional improvements. Willingness self-manage not studied pediatric settings. Study aims were (1) investigate among children parents undergoing intensive (2) determine whether increased influenced outcomes. A total 157 ages 10 18 their enrolled...
Abstract Background: Epidemiological studies in patients with neuropathic pain demonstrate a strong association psychiatric conditions such as anxiety; however, the precipitating pathology between these symptoms remains unclear. To investigate this, we studied effects of lifelong stress on levels pain–like behavior and conversely, chronic injury anxiety-like status male female mice. In addition, assayed this link painful painless diabetic peripheral neuropathy patients. Methods: Male mice...
Abstract Objective The purpose of this study was to explore brain morphological and functional connectivity alterations in adolescents with new daily persistent headache (NDPH) compared pain‐free, healthy controls. Background NDPH is one the most disabling least understood primary conditions. To date, no studies have considered role function structure pediatric patients NDPH. Methods In cross‐sectional study, resting‐state structural images were acquired for 13 ( M age = 15.9, standard...
Chronic pelvic pain (CPP) is a common condition affecting up to 26.6% of women, with many suffering for several years before diagnosis and/or treatment. Its clinical presentation varied and there are frequently comorbid conditions both within outside the pelvis. We aim explore whether specific subgroups women CPP report different symptoms differing impact on their quality life (QoL).The study part Translational Research in Pelvic Pain (TRiPP) project which cross-sectional observational...
Abstract Chronic pelvic pain is heterogeneous with potentially clinically informative subgroups. We aimed to identify subgroups of based on symptom patterns and investigate their associations inflammatory chronic pain-related comorbidities. Latent class analysis (LCA) identified participants (n = 1255) from the Adolescence Adulthood (A2A) cohort. Six participant characteristics were included in LCA: severity, frequency, impact daily activities both menstruation-associated (cyclic)...
Abstract Pain-related fear is typically associated with avoidance behavior and pain-related disability in youth chronic pain. Youth elevated have attenuated treatment responses; thus, targeted highly warranted. Evidence supporting graded vivo exposure (GET) for adults pain considerable, but just emerging youth. The current investigation represents the first sequential replicated randomized single-case experimental phase design multiple measures evaluating GET pain, entitled Living . A cohort...
Abstract We described trends in pelvic pain characteristics over 2 years of follow-up among adolescents and adults with without endometriosis participating the longitudinal observational cohort Women's Health Study: From Adolescence to Adulthood, using data reported at baseline 1 follow-up. Participants completed a questionnaire (between November 2012 May 2019) annually thereafter that included validated measures severity, frequency, life interference dysmenorrhea, acyclic pain, dyspareunia....
Introduction Over four million women in the US alone have been diagnosed with endometriosis. For those living this disease, surgery and hormonal treatment reduce associated pelvic pain some, while others continue to experience life impacting pain. Therefore, identification of accessible cost-effective methods reduction compliment current is urgently needed. Our objective was quantify prevalence complementary alternative used manage acyclic their reported benefit among different age groups...
Objective: To understand the lived experiences and needs of college students with chronic pain living in US UK. Participants: College (n = 115), mean age 21.4 years (SD 1.73). Methods: As part a larger survey, were asked: (1) How, if at all, impacted their experience; (2) Support they did/did not receive from students, faculty, staff, services; (3) What support would be most helpful to them as student pain. Qualitative data analyzed using an immersion/crystallization approach. Results: Four...
Background Conditioned pain modulation (CPM) is considered a human proxy for descending inhibitory pathways. However, there wide variation in the CPM response described literature and ongoing debate about its utility. Methods Here we explored women with ( n = 59) without 26) chronic pelvic (CPP), aiming to determine magnitude of effect factors influencing variability response. Results Using pressure threshold test stimulus ischaemic cuff conditioning (CS), found no significant difference...
Abstract Chronic pelvic pain (CPP), despite its high prevalence, is still relatively poorly understood mechanistically. This study, as part of the Translational Research in Pelvic Pain (TRiPP) project, has used a full quantitative sensory testing (QST) paradigm to profile n = 85 women with and without CPP (endometriosis or bladder specifically). We foot control site abdomen test site. Across 5 diagnostically determined subgroups, we found features which are common across different...