A5075940090- Palliative and Oncologic Care
- Women's cancer prevention and management
- Respiratory Support and Mechanisms
- Healthcare Regulation
- Healthcare during COVID-19 Pandemic
- Science and Education Research
- Head and Neck Cancer Studies
- Intensive Care Unit Cognitive Disorders
- Ferroptosis and cancer prognosis
- Extracellular vesicles in disease
- Health, Nursing, Elderly Care
- Childhood Cancer Survivors' Quality of Life
- Public Health in Brazil
- Nutrition and Health in Aging
- Physical Education and Gymnastics
- Nursing Diagnosis and Documentation
- Dysphagia Assessment and Management
- Education during COVID-19 pandemic
- Therapeutic Uses of Natural Elements
- SARS-CoV-2 detection and testing
- Cancer Research and Treatments
- Colorectal Cancer Treatments and Studies
- Cancer survivorship and care
- Salivary Gland Disorders and Functions
- Cystic Fibrosis Research Advances
Universidade do Oeste de Santa Catarina
2016-2025
University of the West
2024
AC Camargo Hospital
2014-2020
National Council for Scientific and Technological Development
2016
Fundação de Amparo à Pesquisa do Estado de São Paulo
2016
Despite the best efforts of intensive care units (ICUs) professionals, extubation failure rates in mechanically ventilated patients remain range 5%–30%. Extubation is associated with increased risk death and longer ICU stay. This study aimed to identify respiratory non-respiratory parameters predictive outcome, use these predictors develop validate an “Extubation Predictive Score (ExPreS)” that could be used predict likelihood success receiving invasive mechanical ventilation (IMV)....
ABSTRACT Background and Purpose Cancer is one of the most prevalent diseases in general population, main causes changes population's illness profile. In this study, we assessed functional status quality life patients first months chemotherapy treatment. Method A prospective cohort study was carried out, collecting data from cancer seen at an outpatient clinic Midwest Santa Catarina who had breast, lung, colon rectum, prostate head neck cancer. Patients were four different times, diagnosis...
This study aimed to identify predictive factors for response neoadjuvant treatment in patients with stage II and III breast cancer. A cross-sectional evaluated the medical records of 440 treated Oncology Department a University Hospital Brazil between 2007 2022. Response was classified into three groups: pathological complete (pCR), partial response, no response. Predictive were analyzed using multinomial regression. Most showed (73.9%). Patients aged 39 years or younger times more likely...
The western mesoregion of the state Santa Catarina (SC), Southern Brazil, was heavily affected as a whole by COVID-19 pandemic in early 2021. This study aimed to evaluate dynamics SARS-CoV-2 virus spreading patterns SC from March 2020 April 2021 using genomic surveillance. During this period, there were 23 distinct variants, including Beta and Gamma, among which Gamma related lineages predominant second wave within SC. A regionalization P.1-like-II Western region observed, concomitant...
<b>Background:</b> Mechanical ventilation (MV) is a widely used method of life support. Its proper management affects the outcome and depends on expertise operators. However, there significant lack knowledge part most professionals, especially those who have recently graduated. <b>Aim:</b> To develop platform based computer vision artificial intelligence capable automatically evaluating suggesting real-time adjustments to mechanical ventilator parameters. <b>Methods:</b> The NexoVent...
We investigated whether COVID-19 patients on mechanical ventilation (MV) had a different extubation outcome compared to non-COVID-19 while identifying predictive factors of failure in the former.
Although the mortality rate of oropharyngeal squamous cell carcinoma (OPSCC) has been decreasing over last 30 years, there a significant increase in frequency diagnosis this type cancer several countries. Beyond classic prognostic factors, such as TNM stage, is lack predictive factors for recurrence and treatment response. A retrospective analysis patients with OPSCC treated at Oncology Department Santa Terezinha University Hospital between 2007 2012 was performed, aim identifying new...
The A33 protein, expressed in colorectal tumors, is a target for improving treatment of patients with cancer. Over the last decade, studies have tested anti-A33 antibody as therapeutic agent these patients. Preclinical results were promising, but clinical trials did not confirm positive results. Here, immunohistochemistry cancer tissue showed that samples from well-differentiated tumors presented strong membrane staining, whereas poorly differentiated and mucinous adenocarcinomas weak...
Hypereosinophilic syndrome is a rare, chronic hematological disease characterized by persistently elevated eosinophil count exceeding 1.5×109/l, following the exclusion of other potential etiologies. The systemic involvement causes tissue damage through infiltration, and may affect various organs; cardiac complications are observed in 50-60% cases, which predominately attributed to endomyocardial fibrosis. treatment based initially on determining presence FIP1L1-PDGFRA fusion. Patients with...
Germ cell tumors are composed of tissues derived from more than one the three germinal layers. They common in testes and ovaries, but can present many different regions midline, including sacral region, retroperitoneum, mediastinum, brain. Testicular germ generally metastasize to lungs, brain; metastases soft tissue very rare.Here we describe a case single soft-tissue mass thigh 27-year-old man, with histology showing areas mature teratoma ectodermal mesodermal lineages, immature small...
To translate the European Organisation for Research and Treatment of Cancer (EORTC) 29-item Quality Life Questionnaire-Lung Module (QLQ-LC29, developed assessment quality life in patients with lung cancer) to Portuguese, conducting a pilot study Portuguese-language version adapting it use Brazil.
Objetivou-se analisar o aspecto nutricional de pacientes oncológicos em atendimento ambulatorial, Joaçaba-SC. Estudo transversal, que utilizou a avaliação subjetiva global produzida pelo paciente e questionário consumo alimentar, do Ministério da Saúde. Participaram 70 pacientes, idade média 60,3±13,9 anos, 38 (54,3%) homens, 57 (81,4%) sem acompanhamento nutricional, 48 (68,6%) com alimentação regular, 16 (22,9%) adequada seis (8,6%) boa alimentação. O fumo teve associação câncer pulmão...
Introdução: Diretivas Antecipadas de Vontade (DAV) consistem na manifestação prévia da pessoa sobre cuidados que deseja para assistência à sua saúde quando estiver incapacitado se expressar. Todavia, essas diretivas não são amplamente conhecidas pela população, sendo crucial profissionais tenham conhecimento orientar seus pacientes. Objetivos: Verificar o dos saúde, trabalham em UTI dois hospitais, as DAV e obter avaliação modelos preenchimento elaboração. Método: Pesquisa...
<b>Introduction:</b> Failure to wean or extubate patients on mechanical ventilation increases ICU stay, hospital costs and mortality. There are several protocols scores developed predict the extubation outcome, but failure remains around 15%. ExPreS is a predictive score published in 2021 (doi: 10.1371/journal.pone.0248868) have been tested multicenter randomized clinical trial (RTC). Here, we present partial analysis from one center. <b>Objective:</b> To compare capacity of versus standard...
Objectives To evaluate the efficacy of different methods interfacial elastic compression and their association with obesity chronic venous insufficiency (CVI). Methods Forty legs vascular disease 40 control were analyzed. Four applied interface pressure was measured. Blood flow volume peak systolic velocity (SPV) measured before during compression. Results Although there are no general differences correlating higher pressures blood SPV in CVI patients controls, specific related to obesity....
Abstract Background It has been reported that the manual chest compression and decompression (MCCD) maneuver can increase lung volume in patients receiving invasive mechanical ventilation (IMV), but some important questions related to this require answers: how long effects of MCCD on remain, whether there are other respiratory hemodynamic variables. Methods Patients IMV support an intensive care unit (ICU) with signs hypoventilation, hypoexpansion, or atelectasis were eligible receive...
Introdução: A ventilação mecânica (VM) é amplamente utilizada no tratamento de pacientes internados nas unidades terapia intensiva (UTIs), e requer a atuação multiprofissional, com conhecimento desta ferramenta, para estabelecer rotinas protocolos. Este estudo visou identificar percepção dos enfermeiros que trabalham em UTI relação ao seu papel nos cuidados da mecânica, as funções realizam os conhecimentos técnicos possuem tema. Métodos: Participaram pesquisa 25 assistenciais atuam hospitais...
Abstract Introduction Anorectal physiology tests are indicated for patients who have refractory symptoms of constipation, but the best sequence investigation remains controversial. Objective To evaluate influence colonic transit time and anorectal manometry in diagnosis chronic constipation adults. Method This was a study adult with at private clinic city southern Brazil, from January 1, 2009 to December 31, 2018. Those showed warning signs were referred colonoscopy those any anatomical...