Nahla O. Eltai

ORCID: 0000-0003-1710-8985
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About
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Research Areas
  • Antibiotic Resistance in Bacteria
  • Pharmaceutical and Antibiotic Environmental Impacts
  • Salmonella and Campylobacter epidemiology
  • Antibiotic Use and Resistance
  • Enterobacteriaceae and Cronobacter Research
  • Urinary Tract Infections Management
  • Escherichia coli research studies
  • Indoor Air Quality and Microbial Exposure
  • Brucella: diagnosis, epidemiology, treatment
  • Antibiotics Pharmacokinetics and Efficacy
  • Gut microbiota and health
  • Antimicrobial Peptides and Activities
  • Nanoparticles: synthesis and applications
  • Air Quality and Health Impacts
  • Infection Control and Ventilation
  • Clostridium difficile and Clostridium perfringens research
  • Vibrio bacteria research studies
  • Conducting polymers and applications
  • Sepsis Diagnosis and Treatment
  • Identification and Quantification in Food
  • Electrospun Nanofibers in Biomedical Applications
  • Burkholderia infections and melioidosis
  • Gold and Silver Nanoparticles Synthesis and Applications
  • Bacterial Identification and Susceptibility Testing
  • Pneumonia and Respiratory Infections

Qatar University
2018-2025

Hamad Medical Corporation
2023

University of the West of England
2014

Abstract Background The treatment of Enterobacteriaceae family including diarrheagenic E. coli (DEC) has been increasingly complicated due to the emergence resistant strains. Here we report on phenotypic resistance profiles and ESBL genotype virulence Enteroaggregative (EAEC) Enteropathogenic (EPEC) isolated from children hospitalized with acute gastroenteritis in Qatar (AGE). Results were characterized 76 stool positive samples, collected less than 10 years old. Isolates tested for...

10.1186/s12866-020-01732-8 article EN cc-by BMC Microbiology 2020-03-06

Avian Pathogenic Escherichia coli (APEC) is the contributing agent behind avian infectious disease colibacillosis, which causes substantial fatalities in poultry industries that has a significant impact on economy and food safety. Several virulence genes have been shown to be concomitant with extraintestinal survival of APEC. This study investigates antibiotic resistance patterns APEC-associated content isolated from non-healthy healthy broiler chickens commercial farm Qatar. A total 158 E....

10.3390/antibiotics10050564 article EN cc-by Antibiotics 2021-05-11

Abstract Background The β-lactam antibiotics have traditionally been the main treatment of Enterobacteriaceae infections, nonetheless, emergence species producing β- Lactamases has rendered this class largely ineffective. There are no published data on etiology urinary tract infections (UTI) and antimicrobial resistance profile uropathogens among children in Qatar. aim study is to determine phenotypic genotypic profiles resistant with UTI Methods Bacteria were isolated from 727 urine...

10.1186/s13756-018-0381-6 article EN cc-by Antimicrobial Resistance and Infection Control 2018-07-28

It is well documented that food handlers harbor and shed enteric foodborne pathogens causing disease outbreaks. However, little known on antibiotic resistant (AR) bacteria carriage in handlers. The objective of this study was to establish a baseline prevalence fecal AR E. coli among Qatar.Fecal samples were collected from 456 migrant different nationalities arriving Qatar work permit between January 2015 December 2016. These (25 g each) based the availability examination schedule at Medical...

10.1186/s13756-018-0369-2 article EN cc-by Antimicrobial Resistance and Infection Control 2018-06-25

Polysulfone (PS) membranes blended with different loadings of arabic gum (AG) were synthesized using phase inversion method and the antibacterial properties tested a number Gram-negative (Escherichia coli, Klebsiella pneumonia Pseudomonas aeruginosa) Gram-positive (Staphylococcusaureus) bacterial species. It was shown that AG addition to dope polymer solutions essentially changed porous structure, hydrophilicity zeta potential cast PS/AG membranes. These changes due amphiphilic...

10.3390/membranes9020029 article EN cc-by Membranes 2019-02-14

Antimicrobial resistance (AMR) is a global healthcare challenge with substantial morbidity, mortality, and management costs. During the COVID-19 pandemic, there was documented increase in antimicrobial consumption, particularly for severe critical cases, as well noticeable travel social restriction measures that might influenced spectrum of AMR. To evaluate problem, retrospective data were collected on bacterial infections susceptibility patterns Qatar before after pandemic from 1 January...

10.3390/antibiotics13030203 article EN cc-by Antibiotics 2024-02-21

Abstract Antibiotic resistance is a paramount global health issue, with numerous bacterial strains continually fortifying their against diverse antibiotics. This surge in levels primarily stems from the overuse and misuse of antibiotics human, animal, environmental contexts. In this study, we advocate for exploring alternative molecules exhibiting antibacterial properties to counteract escalating antibiotic resistance. We identified synthetic antimicrobial peptide (AMP) by using...

10.1038/s41598-024-58039-1 article EN cc-by Scientific Reports 2024-05-27

Toxoplasma gondii is recognized as one of the most successful zoonotic parasites globally, infecting a wide range hosts including camelids. This infection can lead to serious outcomes such abortion, neonatal death, or fetal abnormalities. Camels play crucial role in economic, ecological, and social landscapes various regions, particularly Middle East, highlighting importance close health monitoring disease screening. Hence this study, sera from 409 dromedary camels (39 males 370 females)...

10.1645/24-32 article EN Journal of Parasitology 2025-02-13

Background/Objectives: The spread of antimicrobial resistance (AMR) is a growing global health concern. Wild animals can play an important role in the amplification and dissemination AMR conservation efforts aiming at controlling diseases vulnerable wild animal populations. These serve as reservoirs for antibiotic genes are key across ecosystems hosts. Therefore, monitoring crucial tackling environment human population. This study investigated phenotypic genotypic Escherichia coli (E. coli)...

10.3390/antibiotics14030248 article EN cc-by Antibiotics 2025-03-01

<title>Abstract</title> Botrytis cinerea, a fungal pathogen known for causing grey mold diseases in post-harvest plant products, presents serious global concern due to its impact on food safety and economic stability. To address this challenge, various studies have explored the use of safe effective fungicides curb growth associated with spoilage. In study, antimicrobial peptides (AMPs) designed through computational methods were tested their antifungal effects <italic>Botrytis...

10.21203/rs.3.rs-6060973/v1 preprint EN cc-by Research Square (Research Square) 2025-04-01

To investigate the in vitro activity of ceftazidime/avibactam and ceftolozane/tazobactam against clinical isolates MDR Pseudomonas aeruginosa from Qatar, as well mechanisms resistance.MDR P. isolated between October 2014 September 2015 all public hospitals Qatar were included. The BD PhoenixTM system was used for identification initial antimicrobial susceptibility testing, while Liofilchem MIC Test Strips (Liofilchem, Roseto degli Abruzzi, Italy) confirmation susceptibility. Ten...

10.1093/jac/dkz379 article EN Journal of Antimicrobial Chemotherapy 2019-08-09

The emergence of antimicrobial resistance (AMR), particularly methicillin-resistant Staphylococcus aureus (MRSA), poses a significant global health threat as these bacteria increasingly become resistant to the most available therapeutic options. Thus, developing an efficient approach rapidly screen MRSA directly from clinical specimens has vital. In this study, we establish closed-tube loop-mediated isothermal amplification (LAMP) method incorporating hydroxy-naphthol blue (HNB) colorimetric...

10.3390/microorganisms12010157 article EN cc-by Microorganisms 2024-01-12

Little is known about the association between respiratory viral infections and their impact on intestinal microbiota. Here, we compared effect of influenza types, A B, shedding in patients’ stools gut microbiota diversity composition. Deep sequencing analysis was performed for V4 region 16S rRNA gene. Fecal samples were collected from 38 adults with active infection 11 age-matched healthy controls. Influenza resulted variations bacterial community composition rather than overall diversity....

10.3390/pathogens10060761 article EN cc-by Pathogens 2021-06-17

Antibiotic resistance is a growing public health problem globally, incurring and cost burdens. The occurrence of antibiotic-resistant bacterial infections has increased significantly over the years. Gram-negative bacteria display broadest range, with species expressing extended-spectrum β-lactamases (ESBLs), AmpC, carbapenemases. All carbapenem-resistant Enterobacteriaceae (CRE) isolates from pediatric urinary tract (UTIs) between October 2015 November 2019 (n = 30). underwent antimicrobial...

10.3390/antibiotics10080972 article EN cc-by Antibiotics 2021-08-12

Hospitals are hotspots for antimicrobial resistance genes (ARGs), and play a significant role in their emergence spread. Large numbers of ARGs will be ejected from hospitals via wastewater systems. Wastewater-based epidemiology has been consolidated as tool to provide real-time information, represents promising approach understanding the prevalence bacteria at community level.To determine bacterial diversity identify ARG profiles hospital pathogens obtained coronavirus disease 2019...

10.1016/j.jhin.2023.08.011 article EN cc-by Journal of Hospital Infection 2023-08-26

Hydrophobic microporous polystyrene (PS) fibers are fabricated by a solvent-induced phase-separation-assisted electrospinning method. Zinc oxide (ZnO) and silver-doped zinc (Ag-ZnO) nanomaterials with variable morphologies added to the PS fibers, investigate influence of multifunctional nanofiller addition on porosity consequent oil-adsorbing properties for different oil types. The doping silver as well uniformity in particle distribution confirmed scanning electron microscopy...

10.1021/acsomega.0c05683 article EN cc-by-nc-nd ACS Omega 2021-03-17

Objectives: This study aims at evaluating the phenotypic and genotypic antimicrobial resistance (AMR) patterns of 18 clinically relevant antibiotics in food animals Qatar. Materials Methods: Fecal samples from camels, cattle, pigeons (300) were collected different slaughterhouses farms. Escherichia coli isolates recovered on selective media, confirmed biochemically, tested for antibiotic susceptibility using a disk diffusion assay. Any isolate that showed to colistin was E-test polymerase...

10.1089/mdr.2019.0402 article EN Microbial Drug Resistance 2020-04-01

This study presents the taxonomic description of two new sponge species that are intimately associated with hyperarid mangrove ecosystem Qatar. The includes a preliminary evaluation sponges' potential bioactivity against pathogens. Chalinula qatari sp. nov. is fragile thinly encrusting vivid maroon colour in life, often oscular chimneys and commonly recorded on pneumatophores intertidal shallow subtidal zone. Suberites luna massive globular-lobate greenish-black externally yellowish orange...

10.1371/journal.pone.0232205 article EN cc-by PLoS ONE 2020-05-13

Colistin, a last-resort antibiotic, is used to treat infections caused by multi-drug-resistant Gram-negative bacteria. Colistin resistance can emerge acquiring the mobile colistin gene, mcr-1, usually plasmid borne. Studies on mcr-1 and its transmissibility are limited in Middle East North Africa (MENA) region. Here, we investigated occurrence of 18 previously collected Escherichia coli isolates from chicken samples Qatar; whole-genome sequencing was performed determine location...

10.3390/antibiotics11060774 article EN cc-by Antibiotics 2022-06-07
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