A5100364726- Aortic aneurysm repair treatments
- Aortic Disease and Treatment Approaches
- Infectious Aortic and Vascular Conditions
- Neuroscience and Neuropharmacology Research
- Vascular Procedures and Complications
- Epilepsy research and treatment
- Electrospun Nanofibers in Biomedical Applications
- Cardiac Valve Diseases and Treatments
- Cardiac, Anesthesia and Surgical Outcomes
- Tryptophan and brain disorders
- Tissue Engineering and Regenerative Medicine
- Peripheral Artery Disease Management
- Renal and Vascular Pathologies
- Advanced materials and composites
- Anatomy and Medical Technology
- Optical Imaging and Spectroscopy Techniques
- Anesthesia and Neurotoxicity Research
- Angiogenesis and VEGF in Cancer
- Orthopaedic implants and arthroplasty
- MicroRNA in disease regulation
- Cerebrovascular and Carotid Artery Diseases
- Carbon Nanotubes in Composites
- Pharmaceutical Economics and Policy
- Hydrogen's biological and therapeutic effects
- Macrophage Migration Inhibitory Factor
Nanjing Drum Tower Hospital
2016-2025
Shaoxing People's Hospital
2025
Zhejiang Chinese Medical University
2011-2025
Capital Medical University
2019-2024
Beijing Sanbo Brain Hospital
2020-2024
Xuzhou Medical College
2023
Hunan Agricultural Products (China)
2022
First Affiliated Hospital of Xi'an Jiaotong University
2022
Hebei University of Engineering
2022
Affiliated Hospital of Hebei University
2022
Redox imbalance and abnormal amyloid protein (Aβ) buildup are key factors in the etiology of Alzheimer's disease (AD). As an antioxidant, hydrogen molecule (H2) has potential to cure AD by specifically scavenging highly harmful reactive oxygen species (ROS) such as •OH. However, due low solubility H2 (1.6 ppm), traditional administration pathway cannot easily achieve long-term effective accumulation foci. Therefore, how continuous release H2in situ is improve therapeutic effect on AD. a...
We describe a new species of Megophryidae frog, Megophrys shunhuangensis sp. nov., from Hunan Province, Southern China. It can be distinguished other known in the subgenus Panophrys by morphological characters, bioacoustic data and molecular divergence mitochondrial 16S rRNA gene similar to that found among Panophrys. M. nov. is characterized relatively small body size, with adult females measuring 37.6 mm males 30.3-33.6 snout vent length; maxillary teeth present, vomerine absent; tongue...
Abstract To investigate the potential role of drug therapy in preventing or exacerbating seizure‐related brain injury prepubescent brain, we administered kainic acid to rats at postnatal day 35. Therapy with daily phenobarbital was started directly before 1 after administered, and continued through 153. Rats receiving had therapeutic concentrations during most 24‐hour dosing period, but also experienced supratherapeutic peak concentrations. The animals were subsequently tested using water...
Increased failure rates due to metallic wear particle-associated adverse local tissue reactions (ALTR) is a significant clinical problem in resurfacing and total hip arthroplasty. Retrieved periprosthetic of 53 cases with corrosion/conventional particles from 285 revision operations for ALTR was selected nano-analyses. Three major classes implants associated ALTR, metal-on-metal arthroplasty (MoM HRA) large head replacement LHTHA) non-metal-on-metal dual modular neck (Non-MoM DMNTHA) were...
Abstract To overcome shortcomings of current small‐diameter vascular prostheses, we developed a novel allogenic graft from decellularized scaffold modified through heparin immobilization and endothelial growth factor (VEGF) coating. The VEGF coating release profiles were assayed by enzyme‐linked immunosorbent assay, the biological activity surface was validated human umbilical vein cells seeding proliferation for 10 days in vitro. In vivo, implanted either or nonmodified as bilateral carotid...
Abstract Successful construction of a small‐diameter bioartificial vascular graft remains great challenge. This study reports on novel tissue engineering grafts (TEVGs) constructed by endothelial progenitor cells and heparin‐coated decellularized vessels (DV). The DVs were fabricated from canine carotid arteries with observable depletion cellular components. After heparin coating, the scaffolds possessed excellent antithrombogeneity. Canine harvested peripheral blood expanded seeded onto...
Purpose: To summarize the experience and outcomes of total endovascular repair thoracoabdominal aortic disease using 3-dimensional (3D) printed models to guide on-site creation fenestrations in stent-grafts. Materials Methods: From April 2018 March 2019, 34 patients (mean age 58±14 years; 24 men) with were treated our department. Nineteen had dissection 15 aneurysm. Preoperatively, a 3D model aorta was made according computed tomography images. In operating room, main stent-graft completely...
Objective: Attention-deficit/hyperactivity disorder (ADHD) is one of the most common neuropsychiatric disorders in children and affects 3% to 5% school-aged children. This study demonstrate whether functional near-infrared spectroscopy (fNIRS) can detect changes concentration oxygenated hemoglobin(oxy-HB) with ADHD typically developing children(TD children). Method: In this study, 14 15 TD were studied. Metabolic signals blood oxygen recorded by using fNIRS during go/no-go task. A statistic...
Objective: To compare outcomes of hybrid (combined surgical and endovascular) procedures (HYBRID) with open reconstructions (OPEN) in patients multilevel infrainguinal artery occlusive diseases. Design: Case series study retrospective analysis prospectively collected nonrandomized data. Methods: Between 2008 2012, 64 underwent OPEN 43 HYBRID. Patient characteristics, technique success, clinical improvement, procedure-related morbidity were reviewed compared. Patency rates limb salvages...
Histone methylation is considered to play an important role in the occurrence and development of periodontitis. Plant homeodomain finger protein 8 (PHF8), a histone demethylase, has been shown regulate inflammation osteogenic differentiation bone marrow stromal cells (BMSCs). This study aimed detect functions PHF8 TLR4 inflammatory environment induced by Porphyromonas gingivalis lipopolysaccharide (Pg-LPS) METHODS: A periodontitis mouse model was established, mice were treated with TAK-242....
Abstract Evaluation of the oxygen‐mediated effects clinical and daily activities demands an on‐skin device that can track multi‐vital regional tissue hemodynamics simultaneously. For example, peripheral arterial disease (PAD) is third most prevalent cardiovascular disease, but means diagnosing monitoring this are limited because affected area usually in non‐pulsatile away from heart. Herein, we report on ultrathin ultralight near‐infrared optoelectronic biosensor for diagnosis rehabilitation...
Background Malignant tumors represented by breast cancer still have limitations in clinical treatment methods. Matrine is a compound with anticancer activity, but its inhibitory effect on and mechanism for regulating miR-188 are unclear. Purpose Therefore, it necessary to explore more effective methods understand the intervention of matrine miR-188. Methods A nude mouse model was this study constructed divided into group, 4 mg/kg 8 drug mimic group. Different concentrations were administered...
Aortic arch aneurysm is a life-threatening cardiovascular disorder that requires timely medical intervention. Aneurysms in Zone 1 typically involve multiple branch arteries, making repair challenging. Open surgical often results significant trauma, massive blood loss, and prolonged operative time. With advancements endovascular technology, fenestrated/branched thoracic aortic (F/B TEVAR) has been employed for artery reconstruction. Stent grafts F/B TEVAR require personalized modification...