Derk Brouwer

ORCID: 0000-0003-1750-3715
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About
Contact & Profiles
Research Areas
  • Air Quality and Health Impacts
  • Pesticide Exposure and Toxicity
  • Occupational exposure and asthma
  • Nanoparticles: synthesis and applications
  • Chemical Safety and Risk Management
  • Contact Dermatitis and Allergies
  • Occupational Health and Safety Research
  • Indoor Air Quality and Microbial Exposure
  • Air Quality Monitoring and Forecasting
  • Occupational and environmental lung diseases
  • Insect and Pesticide Research
  • Noise Effects and Management
  • Safe Handling of Antineoplastic Drugs
  • Plant Surface Properties and Treatments
  • Animal testing and alternatives
  • Recycling and Waste Management Techniques
  • Greenhouse Technology and Climate Control
  • Pesticide Residue Analysis and Safety
  • Agricultural safety and regulations
  • Risk and Safety Analysis
  • Environmental Impact and Sustainability
  • Environmental and Social Impact Assessments
  • Immunotoxicology and immune responses
  • Vehicle emissions and performance
  • Allergic Rhinitis and Sensitization

University of the Witwatersrand
2015-2025

University of South Africa
2024

Netherlands Organisation for Applied Scientific Research
1994-2017

Pension Fund for Care and Well-Being
2005-2016

Netherlands Environmental Assessment Agency
2004-2009

Food & Nutrition
1995-2006

University of Aberdeen
1999-2001

Institute of Occupational Medicine
1999-2001

Danish National Institute of Public Health
1999

Wageningen University & Research
1999

Dermal exposure, primarily to pesticides, has been measured for almost half a century. Compared with exposure by inhalation, limited progress made towards standardisation of methods measurement and development biologically relevant measures. It is suggested that the absence consistent terminology theoretical model an important cause this lack progress. Therefore, based on multicompartment assessment dermal proposed describes transport contaminant mass from source hazardous substance surface...

10.1136/oem.56.11.765 article EN Occupational and Environmental Medicine 1999-11-01

Recently, toxicological and epidemiological studies on health effects related to particle exposure suggest that 'ultrafine particles' (particles with an aerodynamic diameter of <100 nm) may cause severe after inhalation. Although the mechanisms for these have not yet been explained, it is apparent measuring exposures against mass alone sufficient. It also necessary consider surface area number concentration. From earlier research was hypothesized results concentration distributions vary...

10.1093/annhyg/meh040 article EN The Annals of Occupational Hygiene 2004-07-01

Stoffenmanager Nano (version 1.0) is a risk-banding tool developed for employers and employees to prioritize health risks occurring as result of exposure manufactured nano objects (MNOs) broad range worker scenarios assist implementation control measures reduce levels. In order the risks, combines available hazard information substance with qualitative estimate potential inhalation exposure. The development started review literature on banding. Input parameters assessment MNOs were selected...

10.1093/annhyg/mer113 article EN The Annals of Occupational Hygiene 2012-01-21

Control banding (CB) has been developed as a pragmatic tool to manage the risk resulting from exposure wide variety of potentially hazardous substances in absence firm toxicological and information. Currently, CB approach is applied for emerging risks such nanoparticles, by development various CB-based tools. Six these are compared. Despite their similarity, i.e. combining hazard into control or bands, structure, applicability domains, assignment show differences that may affect consistency...

10.1093/annhyg/mes039 article EN The Annals of Occupational Hygiene 2012-06-15

A D-grade type coal was burned under simulated domestic practices in a controlled laboratory set-up, order to characterize the emissions of volatile organic compounds (VOCs); namely, benzene, toluene, ethylbenzene, and xylenes (BTEX). Near-field concentrations were collected shack-like structure constructed using corrugated iron, simulating traditional house found informal settlements South Africa (SA). Measurements carried out Synspec Spectras GC955 real-time monitor over three-hour burn...

10.3390/ijerph16010095 article EN International Journal of Environmental Research and Public Health 2018-12-31

Hand wash and skin wipes are major techniques that have been used for dermal exposure sampling. Both remove chemicals either deposited on or transferred to the contaminant layer by a combination of chemical mechanical actions. The paper overviews identified methods techniques, with emphasis sampling parameters efficiency. It is concluded protocols, including deviate at possible key issues, which hampers comparisons study results. recommended conduct efficiency studies prior field sampling,...

10.1093/annhyg/44.7.501 article EN The Annals of Occupational Hygiene 2000-11-01

This paper describes a new method (DREAM) for structured, semi-quantitative dermal exposure assessment chemical or biological agents that can be used in occupational hygiene epidemiology. It is anticipated DREAM could serve as an initial of exposure, amongst others, resulting ranking tasks and subsequently jobs. consists inventory evaluation part. Two examples workers car-construction company show characterizes gives insight into mechanisms, forming basis systematic reduction. supplies...

10.1093/annhyg/meg012 article EN The Annals of Occupational Hygiene 2002-12-28

10.1016/0048-9697(95)04617-a article EN The Science of The Total Environment 1995-06-16

The world-wide production of carbon nanotubes (CNTs) has increased substantially in the last decade, leading to occupational exposures. There is a paucity exposure data workers involved commercial CNTs. goals this study were assess personal multi-walled (MWCNTs) during synthesis and handling MWCNTs facility link these levels specific activities. Personal full-shift filter-based samples collected, MWCNTs, R&D activities, office work. concentrations MWCNT evaluated on basis EC concentrations....

10.1093/annhyg/mev082 article EN The Annals of Occupational Hygiene 2015-11-26

Background:Occupational exposure to manufactured nano-objects and their agglomerates, aggregates (NOAA) has been described in several workplace air monitoring studies. However, data pooling for general conclusions estimates are hampered by limited across the occupational life cycle of NOAA a lack comparability between methods collecting analysing data. By applying consistent method data, this study aimed provide information about levels various stages Netherlands which can also be used...

10.1093/annhyg/mev023 article EN The Annals of Occupational Hygiene 2015-04-06

Exposure to volatile organic compounds (VOCs) in nail salons poses risks of acute and chronic health effects for technicians. The objectives this study were investigate differences VOC exposure self-reported symptoms among formal informal technicians assess the non-carcinogenic carcinogenic using a probabilistic approach. A questionnaire was administered 54 60 elicit information on sociodemographic characteristics, work conditions, symptoms. Passive sampling employed measure personal...

10.3390/ijerph22030330 article EN International Journal of Environmental Research and Public Health 2025-02-24

Introduction Antineoplastic drugs (ADs) are hazardous substances commonly used in medical oncology, posing health risks to pharmacy personnel through occupational exposure. Despite safety guidelines, contamination of surfaces oncology pharmacies remains prevalent. In this study, we assessed surface and biological uptake ADs selected South African pharmacies. Methods Six (three from each two service providers, SP1 SP2) participated. Surface wipe samples were collected three areas...

10.1177/10781552251321150 article EN cc-by Journal of Oncology Pharmacy Practice 2025-02-24
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