Abstract Despite substantial progress in the development of wearable and flexible monitoring systems that conform to epidermis, most designs focus on either physiological signs such as electrocardiogram (ECG) results, respiration rate, or metabolites, ignore dynamic fluctuations pH temperature sweat during on‐body tests. An advanced butterfly‐inspired hybrid epidermal biosensing ( bi ‐HEB) patch is presented here, which interfaced with a custom‐developed miniaturized system. The incorporates...

Abstract While state‐of‐the‐art skin‐adhering fibrous electrodes have distinct benefits in personal wearable bioelectronics, considerable challenges persist the production of fibrous‐based soft conductive biosensing nanomaterials and their integration into efficient multisensing platforms. Here, an electrochemical‐electrophysiological multimodal patch based on MXene/fluoropolymer nanofiber‐derived hierarchical porous TiO 2 nanocatalyst interconnected 3D carbon nanohybrid is reported. The...

Despite extensive advances in wearable monitoring systems, most designs focus on the detection of physical parameters or metabolites and do not consider integration microfluidic channels, miniaturization, multimodality. In this study, a combination multimodal (biochemical electrophysiological) biosensing channel-integrated patch-based wireless systems is designed fabricated using flexible materials for improved wearability, ease operation, real-time continuous monitoring. The reduced...

Potentiometric detection in complex biological fluids enables continuous electrolyte monitoring for personal healthcare; however, the commercialization of ion-selective electrode-based devices has been limited by rapid loss potential stability caused electrode surface inactivation and biofouling. Here, we describe a simple multifunctional hybrid patch incorporating an Au nanoparticle/siloxene-based solid contact (SC) supported substrate made laser-inscribed graphene on poly(dimethylsiloxane)...

Abstract The breathability of wearable sensors is utmost necessity as it facilitates heat dissipation and sweat evaporation from the skin–sensor interface for improving user's comfort minimizing inflammation risk. In this work, a Siloxene/porous styrene–ethylene–butylene–styrene (SEBS)‐based breathable triboelectric sensor newly designed fabricated increasing user reliability. reliability evaluated by measuring through using thermal IR imaging test. Similarly, sensor's quantified water vapor...

Abstract Although metal‐organic framework (MOF)‐derived nanoporous C (NPC) materials offer several advantages for electrochemical sensor applications, surface functionalization and porosity tuning can affect performance. This study presents the development of a skin patch perspiration electrocardiogram (ECG) monitoring, leveraging unique properties MOF‐on‐MOF‐derived surface‐functionalized hybrid (f‐HNPC) incorporated into laser‐scribed graphene (LSG). Hydroxyl (OH) group‐functionalized NPC,...

Abstract Hierarchically interactive 3D‐porous soft carbon nanofibers (CNFs) have great potential for wearable bioelectronic interfaces, yet 90% of CNFs are derived from expensive polyacrylonitrile associated with complex production methods. Here, another cost‐effective fluoropolymer, poly(1,1‐difluoroethylene) (PDFE), is introduced to investigate its transition chemistry and structural evolution over laser‐induced carbonization (LIC). The impregnation Ti 3 C 2 T x ‐MXene followed by...

Triboelectric Nanogenerators In article number 2302471, Jae Y. Park and co-workers develop a breathable triboelectric sensor that promotes sweat evaporation heat dissipation through the skin-sensor interface. This ensures high reliability of wearable sensors for human-machine interactions soft-robotics systems.

Affinity-based electrochemical (AEC) biosensors have gained more attention in the field of point-of-care management. However, AEC sensing is hampered by biofouling electrode surface and degradation antifouling material. Therefore, a breakthrough nanomaterials crucial for fabrication reliable biosensors. Herein, first time, we propose 1-pyrenebutyric acid-functionalized MXene to develop an nanocomposite resist immunosensors. The consisted 3D porous network bovine serum albumin cross-linked...

Abstract The demand for non‐invasive health monitoring with wearables poses challenges in developing sustainable, self‐powered systems, as current energy harvesters face issues like complex fabrication, low robustness, and insufficient power density continuous biosensing. In this study, a wearable biosensing platform combining electromagnetic‐triboelectric hybrid generator (ETHG) an advanced electrochemical sweat‐ion‐sensing patch is proposed. A Halbach magnet array within the...

Hybrid Epidermal Biosensing System In article number 2208344, Jae Yeong Park and co-workers reported in-depth investigations of electrophysiological parameters with precise glucose level determination using a butterfly inspired hybrid epidermal biosensing (bi-HEB) patch. As portable smart healthcare monitoring system, the [email protected] bi-HEB patch was successfully paired miniaturized printed circuit board to assess electrocardiogram individuals during exercise.

Wearable microneedle-based glucose sensor is a highly promising device for long-term continuous monitoring. In particular, it essential to develop minimally invasive with long lifetime, wide linear range, and low limit of detection by ensuring enzyme stability reducing biofouling. this study, we present fully integrated polymeric microneedle system wireless in vivo testing real-time sensing levels interstitial fluid (ISF). The developed compatible customized mobile apps data visualization...

This paper reports, for the first time, a butterfly-inspired microelectromechanical system (MEMS)-based hybrid wearable biosensing patch that can simultaneously measure biochemical and electrophysiological parameters. The is comprised of glucose biosensor along with pH temperature (T) sensors precise quantification as well two biopotential recording electrodes, enabling real-time measurements electrocardiogram (ECG) signals. working electrodes (WE) are activated novel transducing layer...

The controlled transport of molecules through cell membrane nanopores holds significant promise for various biomedical applications, ranging from gene transfection and cancer chemotherapy to transdermal drug delivery. Among the diverse array membrane-active agents, antimicrobial peptides (AMPs) have garnered substantial interest due their antibacterial antifungal properties. Magainin 2, initially uncovered within African clawed frog Xenopus laevis, is one such AMP known interact with lipid...

Laser-Carbonization In article number 2208894, Jae Y. Park and co-workers, report an electrochemical-electrophysiological multimodal biosensing patch based on MXene/fluoropolymer nanofibers (MFNFs)-derived hierarchical porous TiO2 nanocatalyst interconnected three-dimensional fibrous carbon nanohybrid electrodes. The electrode is produced via a one-step laser carbonaceous thermal oxidation of MFNFs. modified integrated into textile demonstrated to be capable simultaneously precisely...

Affinity-based electrochemical (EC) sensors have emerged as a promising solution for point-of-care (POC) diagnostics. However, commercialization of EC is hampered by biofouling the electrode surface and rapid oxidation antifouling material. Therefore, breakthrough in nanomaterial crucial reliable biosensors diagnostic applications. Herein, first time, we synthesized an ultra-stable, highly conductive oxidation-resistive MXene nanosheet (Al-Ti3C2Tx) to develop nanocomposite (3D-MXting)...

For the unobtrusive monitoring of sodium and potassium ions, an electrochemical epidermal patch based on Au nanoparticles a siloxene-functionalized laser-ablated graphene electrode has been developed. The siloxene sheets coated working electrodes significantly increase contact area due to their laminar structure. Furthermore, electrodeposited further overall surface solid material resulting in enhanced electric double-layer capacitance at interface between ion-selective membranes solid-state...

Breathable Bioelectronics In article number 2107969, Jae Y. Park and co-workers develop hierarchically interactive carbon nanofibers from β-phase rich dehydrofluorinated MXene-poly(1,1-difluoroethylene) electrospun via laser-induced carbonization. The is converted into an sp2-hybridized graphitic structure by cyclization/cross-linking decomposition of hydrogen fluoride transforms a conjugated during approach generates flexible with high yield, conductivity, stability appropriate for...