A5100372262- Radiomics and Machine Learning in Medical Imaging
- MRI in cancer diagnosis
- Advanced Neuroimaging Techniques and Applications
- Medical Imaging Techniques and Applications
- AI in cancer detection
- Plasma Diagnostics and Applications
- Advanced MRI Techniques and Applications
- Plasma Applications and Diagnostics
- Aerosol Filtration and Electrostatic Precipitation
- Cardiac Imaging and Diagnostics
- Reproductive Biology and Fertility
- Breast Cancer Treatment Studies
- Corneal surgery and disorders
- Ophthalmology and Visual Impairment Studies
- Autophagy in Disease and Therapy
- Colorectal Cancer Surgical Treatments
- Glaucoma and retinal disorders
- Eosinophilic Esophagitis
- Cardiovascular Disease and Adiposity
- Sperm and Testicular Function
- Gastroesophageal reflux and treatments
- Ocular Surface and Contact Lens
- Aquaculture Nutrition and Growth
- Forensic Toxicology and Drug Analysis
- Ophthalmology and Visual Health Research
Chinese Academy of Medical Sciences & Peking Union Medical College
2013-2025
Ruijin Hospital
2021-2024
Shanghai Jiao Tong University
2021-2024
South China University of Technology
2024
Tianjin Medical University
2024
Tianjin Medical University Eye Hospital
2017-2024
Taiyuan University of Technology
2022-2024
Peking University
2024
Peking Union Medical College Hospital
2024
Shandong First Medical University
2024
Staphylococcus aureus can cause severe infections, including bacteremia and sepsis. The spread of methicillin-resistant (MRSA) highlights the need for novel treatment options. Sodium new houttuyfonate (SNH) is an analogue houttuynin, main antibacterial ingredient Houttuynia cordata Thunb. aim this study was to evaluate in vitro activity SNH its potential synergy with antibiotics against hospital-associated MRSA.A total 103 MRSA clinical isolates recovered two hospitals Beijing were evaluated...
Addiction, particularly in relation to psychostimulants and opioids, persists as a global health crisis with profound social economic ramifications. Traditional interventions, including medications behavioral therapies, often encounter limited success due the chronic relapsing nature of addictive disorders. Consequently, there is significant interest development innovative therapeutics counteract effects abused substances. In recent years, vaccines have emerged novel promising strategy...
Objective To investigate changes in the choroidal vasculature and their correlations with visual acuity diabetic retinopathy (DR). Methods The cohort was composed of 225 eyes from subjects, including 60 subjects healthy control, 55 without DR, 46 nonproliferative (NPDR), 21 proliferative (PDR), 43 clinically significant macular edema (CSME). Swept-source optical coherence tomography (SS-OCT) used to image a 12-mm radial line scan protocol. parameters for 6-mm diameters region centered on...
Background In our clinical work, we found that cancer patients were susceptible to coronary atherosclerotic heart disease (CAD). However, less is known about the relationship between CAD and cancer. The present study aimed identify risk factors for cancer, as well Methods this retrospective study, 1600 January 2012 June 2019 enrolled divided into groups according whether they had or Single-factor multivariate analysis methods applied examine Results (1) Cancer prevalence was significantly...
Cell-penetrating peptides (CPPs) are invaluable tools for delivering various substances into cells by crossing biological membranes. However, the effects of cell-penetrating peptide fusion proteins on activity antibodies remain to be fully understood. Here, we engineered a recombinant protein, LP-scFv, which combines single-chain variable region anti-human epidermal growth factor receptor-2 with novel and non-oxic as leader peptide. The introduction this led more than twofold increase in...
Background: To investigate the relationship between high-order aberration (HOA) changes and RCST/CT (residual corneal stroma thickness/corneal thickness) after femtosecond LASIK surgery.Methods: A total of 65 eyes from 39 patients with high myopia, who had (FS) laser-assisted in situ keratomileusis (LASIK) surgery performed our hospital, were included this study. HOA central thickness measured preoperatively at 1 week, month, 3 months FS-LASIK by Sirius Scheimpflug-Placido topography....
Background Machine learning classifiers are increasingly used to create predictive models for pathological complete response (pCR) in breast cancer after neoadjuvant therapy (NAT). Few studies have compared the effectiveness of different ML classifiers. This study evaluated radiomics based on pre- and post-contrast first-phase T1 weighted images (T1WI) predicting pCR NAT performance Methods retrospective enrolled 281 patients undergoing from Duke-Breast-Cancer-MRI dataset. Radiomic features...
The nanosecond (ns) pulse excited plasma jet array shows merits of large treatment area and high chemical reactivity, while the parameters influence downstream uniformity ns significantly. In this paper, pulsed with linear-field electrode structure is investigated by discharge image measurement at different amplitude applied voltage, rising time repetition frequency (PRF). voltage-current waveform Schlieren are measured electrical field distribution simulated to reveal interaction...
Atmospheric-pressure plasma jet (APPJ) array could effectively enlarge the treatment area for requirement of application efficiency. The downstream uniformity is determinant even processing effect. In this paper, a three-jet 1-D APPJ with electrode structure needle-ring constructed, and position needle (high-voltage electrode) adjusted to investigate influence arrangement on array. results show that relative difference positions middle side electrodes d has great uniformity. When distances...
Atmospheric pressure low-temperature plasma is a promising tool in biomedicine applications including blood coagulation, bacterial inactivation, sterilization, and cancer treatment, due to its high chemical activity limited thermal damage. It of great importance develop portable sources that are safe human touch suitable for outdoor household operation. In this work, rechargeable spark discharge device (130 mm × 80 35 mm, 300 g) was designed. The frequency plume length were optimized by the...
Suspicious breast lesions [Breast Imaging Reporting and Data System (BI-RADS) category 4 or 5] detected only by magnetic resonance imaging (MRI) invisible on other initial modalities (MRI-only lesions) are usually small poorly characterized in previous literature, thus making diagnosis management difficult. This study aimed to investigate the clinical significance of quantitative apparent diffusion coefficient (ADC) metrics derived from conventional diffusion-weighted (DWI) evaluating...
Intracellular free calcium ([Ca 2+ ] i ) is essential for oocyte maturation and early embryonic development. Here, we investigated the role of [Ca in oocytes from cumulus‐oocyte complexes (COCs) with respect to development, using calcium‐buffering agent BAPTA‐AM (1,2‐bis[2‐aminophenoxy]ethane‐ N,N,N′,N′ ‐tetraacetic acid tetrakis [acetoxymethyl ester]). COCs were graded based on compactness cumulus mass appearance cytoplasm, Grade 1 indicating higher quality developmental potential than 3....