- Transcranial Magnetic Stimulation Studies
- Cerebrospinal fluid and hydrocephalus
- Intracranial Aneurysms: Treatment and Complications
- EEG and Brain-Computer Interfaces
- Muscle activation and electromyography studies
- Motor Control and Adaptation
- Neuroscience and Neuropharmacology Research
- Stroke Rehabilitation and Recovery
- Intracerebral and Subarachnoid Hemorrhage Research
- Epilepsy research and treatment
- Cerebrovascular and Carotid Artery Diseases
- Spinal Fractures and Fixation Techniques
- Spatial Neglect and Hemispheric Dysfunction
- Neuroscience and Music Perception
- Meningioma and schwannoma management
- Vascular Malformations Diagnosis and Treatment
- Glioma Diagnosis and Treatment
- Traumatic Brain Injury and Neurovascular Disturbances
- Acute Ischemic Stroke Management
- Neurobiology of Language and Bilingualism
- Moyamoya disease diagnosis and treatment
- Fetal and Pediatric Neurological Disorders
- CNS Lymphoma Diagnosis and Treatment
- Stuttering Research and Treatment
- Neurosurgical Procedures and Complications
Utano Hospital
2008-2024
National Hospital Organization
2023-2024
Nagahama City Hospital
2014-2023
Shiga Medical Center
2008-2015
Shiga Medical Center for Adults
2009-2012
Kyoto University
2002-2008
Tenri Hospital
2000-2001
Summary: Purpose: This study was conducted to investigate the effect of low‐frequency electric cortical stimulation on epileptic focus in humans. Methods: We stimulated a patient with medically intractable mesial temporal lobe epilepsy (MTLE) by means subdural electrodes and evaluated change number interictal epileptiform discharges. used biphasic current 0.3‐ms duration presented at 0.9‐Hz frequency for 250 s, comparing stimulus intensity 7.5, 2, 0.5 mA. Results: Interictal discharges ictal...
Taking an advantage of the high sensitivity 3D T2*-weighted gradient-recalled-echo (GRE) imaging to cerebral microbleeds, we investigated relationship between microbleeds and leukoaraiosis.Participants aged 40 years or more have been evaluated for presence using T2*-GRE sequence since 2006. The severity periventricular hyperintensity (PVH) deep white matter (DWMH) on fluid attenuated inversion recovery images was assessed Fazekas rating scales. Multivariate logistic regression analyses were...
We investigated the role of cerebral cortex, particularly face/tongue area primary sensorimotor (SMI) cortex (face/tongue) and supplementary motor (SMA), in volitional swallowing by recording movement-related cortical potentials (MRCPs). MRCPs with tongue protrusion were recorded from scalp electrodes eight normal right-handed subjects implanted subdural six epilepsy patients. The experiment EEG revealed that premovement Bereitschaftspotentials (BP) activity for was largest at vertex...
The functional changes that occur throughout the human brain after selective removal of an epileptogenic lesion remain unclear. Subtemporal amygdalohippocampectomy (SAH) has been advocated as a minimally invasive surgical procedure for patients with medically intractable mesial temporal lobe epilepsy (MTLE). We evaluated effects subtemporal SAH on cerebral glucose metabolism and memory function in 15 MTLE hippocampal sclerosis using [18F]-fluorodeoxyglucose PET (FDG-PET) Wechsler Memory...
To test whether low-frequency repetitive transcranial magnetic stimulation (rTMS) of sensorimotor cortex (SM1) has prolonged effects on somatosensory function, eight subjects were given 900 TMS pulses over the left hand SM1 (0.9Hz, 90% resting motor threshold) or at sites 3 cm anterior posterior to it. Tactile threshold right was increased for a short duration after rTMS SM1, but two-point discrimination and median nerve SEPs unaffected any sites.
We studied the generator location of premovement subcomponents movement‐related cortical potentials (MRCPs) [Bereitschaftspotential (BP), negative slope (NS′) and motor potential (MP)] associated with voluntary, self‐paced horizontal saccade in human frontal lobe. Self‐paced saccade, wrist (or middle finger) extension foot dorsiflexion were employed 10 patients (lateral surface lobe seven mesial three) as part presurgical evaluation, data five four used final analysis. On lateral lobe,...
Idiopathic normal pressure hydrocephalus (iNPH) is a highly prevalent condition in the elderly population; however, underlying pathophysiology relation to aging process remains unclear. To investigate effect of removal cerebrospinal fluid by lumbar "tap test" on cerebral circulation iNPH patients, 14 "probable" patients were studied using novel blood tracking technique based oxygenation level-dependent (BOLD) magnetic resonance signal intensity. By propagation low-frequency component BOLD...
Summary: Purpose: Atonic seizures are commonly seen in patients with generalized epilepsy but only infrequently partial epilepsy. Clinically atonic as a have not been studied detail video/EEG monitoring. Here we describe the clinical and physiologic characteristics of due to discuss underlying mechanism. Methods: Two manifesting seizures, one frontal lobe (FLE) other parietal (PLE), were reported. The long‐term monitoring, magnetic resonance imaging (MRI), interictal...
Summary: Purpose: Decline in verbal memory as a surgical complication remains an unresolved problem mesial temporal lobe epilepsy. Some areas the associated with language function, often including basal area, have been removed or transected by conventional procedures. The authors defined area and only epileptogenic zone subtemporal approach. Methods: was evaluated using long‐term subdural electrodes five patients language‐dominant–side While preserving this hippocampus parahippocampal gyrus...
OBJECTIVE: To minimize therapeutic morbidity such as cognitive function disturbance and vascular injury to perforating arteries, preoperative functional mapping of the basal temporal lobe functions was performed medial lesions were resected via a combined subtemporal transventricular/transchoroidal fissure approach. METHODS: Twenty-one patients with including tumors, arteriovenous malformations, epilepsy underwent operation. The neurovascular structures in ambient cistern first dissected...
Difficulty swallowing due to damage of the vagus nerve is one most devastating complications surgery in and around medulla oblongata; therefore, intraoperative anatomical functional evaluation this crucial. The authors applied endotracheal tube surface electrodes record electromyography (EMG) activity from vocal cords innervated by nerve. vagal nucleus or rootlet was electrically stimulated during vocalis muscle EMG activities were displayed auditory visual signals. This technique used...
Cobb syndrome is a rare, noninherited, neurocutaneous disease characterized by vascular abnormality of the spinal cord and associated with lesions in skin at same metamere. The majority are arteriovenous malformations, mostly port-wine angiomas. authors report first case multiple intramedullary cavernous angiomas (CAs) accompanied CAs within A 42-year-old man presented an acute onset gait disturbance, low-back pain, urinary incontinence. Magnetic resonance imaging thoracolumbar spine showed...
Walking ability is important in stroke patients to maintain daily life. Nevertheless, its improvement limited with conventional physical therapy chronic stage. We report the case of a patient showing remarkable gait function after new neurorehabilitation protocol using transcranial direct current stimulation (tDCS) and neuromuscular electrical (NMES).A 62-year-old male left putaminal hemorrhage suffered from severe right hemiparesis. He could move by himself wheelchair 1 year ictus. Anodal...