A5057877410- Forensic Entomology and Diptera Studies
- Paleopathology and ancient diseases
- Forensic Anthropology and Bioarchaeology Studies
- Metabolomics and Mass Spectrometry Studies
- Forensic and Genetic Research
- Skin and Cellular Biology Research
- Yersinia bacterium, plague, ectoparasites research
- Molecular Biology Techniques and Applications
- Metabolism and Genetic Disorders
- Mass Spectrometry Techniques and Applications
- Advanced Chemical Sensor Technologies
- Gut microbiota and health
- Diet and metabolism studies
- Pelvic floor disorders treatments
Lincoln Memorial University
2021-2022
University of Tennessee at Knoxville
2015-2020
Knoxville College
2017
Abstract Postmortem succession of human‐associated microbial communities (“human microbiome”) has been suggested as a possible method for estimating postmortem interval (PMI) forensic analyses. Here we evaluate human gut bacterial populations to determine quantifiable, time‐dependent changes postmortem. Gut microflora were repeatedly sampled from the proximal large intestine 12 deceased individuals they decayed under environmental conditions. Three intestinal genera quantified by...
The human microbiome has demonstrated an importance for the health and functioning in living individuals. However, fate of after death is less understood. In addition to a better understanding microbe-mediated decomposition processes, postmortem succession human-associated microbial communities been suggested as possible forensic tool estimating time since death, or interval (PMI). objective our study was document changes gut bacterial communities. Gut microflora were repeatedly sampled from...
Ceramides have been implicated in a number of disease processes. However, current means evaluation with flow infusion analysis (FIA) limited primarily due to poor sensitivity within our high-resolution mass spectrometry lipidomics analytical platform. To circumvent this deficiency, we investigated the potential chloride adducts as an alternative method improve electrospray ionization. Chloride ceramides and ceramide subfamilies provided 2- 50-fold increases both standards biological samples....
Human brain lipidomics have elucidated structural lipids and lipid signal transduction pathways in neurologic diseases. Such studies traditionally sourced tissue exclusively from bank biorepositories, however, limited inventories that these facilities may not be able to keep pace with this growing research domain. Formalin fixed, whole body donors willed academic institutions offer a potential supplemental source, the profiles of which yet described. To determine subjects analysis, levels...
The human microbiome has demonstrated importance for health and functioning in living individuals. However the fate of after death is poorly understood. In addition to a better understanding microbe-mediated decomposition processes, postmortem succession human-associated microbial communities been suggested as possible forensic tool estimating time since death, or interval (PMI). objective our study was document changes gut bacterial communities. Gut microflora were repeatedly sampled from...
The human microbiome has demonstrated importance for health and functioning in living individuals. However the fate of after death is poorly understood. In addition to a better understanding microbe-mediated decomposition processes, postmortem succession human-associated microbial communities been suggested as possible forensic tool estimating time since death, or interval (PMI). objective our study was document changes gut bacterial communities. Gut microflora were repeatedly sampled from...