Caroline Steele

ORCID: 0000-0003-1785-5761
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About
Contact & Profiles
Research Areas
  • Pituitary Gland Disorders and Treatments
  • Growth Hormone and Insulin-like Growth Factors
  • Diabetes and associated disorders
  • Pediatric Pain Management Techniques
  • Gastric Cancer Management and Outcomes
  • Hyperglycemia and glycemic control in critically ill and hospitalized patients
  • Esophageal Cancer Research and Treatment
  • Medical Imaging and Pathology Studies
  • Celiac Disease Research and Management
  • Immunodeficiency and Autoimmune Disorders
  • Parathyroid Disorders and Treatments
  • Glioma Diagnosis and Treatment
  • Thyroid Disorders and Treatments
  • Thyroid Cancer Diagnosis and Treatment
  • Neurological Disease Mechanisms and Treatments
  • Obesity and Health Practices
  • Mitochondrial Function and Pathology
  • Physical Activity and Health
  • Ovarian function and disorders
  • Congenital heart defects research
  • Cardiovascular Disease and Adiposity
  • Adrenal and Paraganglionic Tumors
  • Lung Cancer Treatments and Mutations
  • Astro and Planetary Science
  • Barrier Structure and Function Studies

University of Southampton
2025

Royal Victoria Infirmary
2021

Newcastle University
2021

Newcastle upon Tyne Hospitals NHS Foundation Trust
2021

Great North Children's Hospital
2021

Leeds Teaching Hospitals NHS Trust
2018-2021

Royal Manchester Children's Hospital
2015

The Rotherham NHS Foundation Trust
2015

University of Liverpool
2010-2013

Aintree University Hospital
2013

To study the presentation, management and outcomes to apply retrospectively Pituitary Apoplexy Score (PAS) (United Kingdom (UK) guidelines for of apoplexy) a large, single-centre series patients with acute pituitary apoplexy. Retrospective analysis casenotes at single neurosurgical centre in Liverpool, UK. Fifty-five [mean age, 52·4 years; median duration follow-up, 7 years] were identified; 45 55 (81%) had nonfunctioning adenomas, four acromegaly six prolactinomas. Commonest presenting...

10.1111/cen.12307 article EN Clinical Endocrinology 2013-08-05

To evaluate physicians' adjustments of insulin pump settings based on continuous glucose monitoring (CGM) for patients with type 1 diabetes and to compare these automated dose adjustments.A total 26 physicians from 16 centres in Europe, Israel South America participated the study. All were asked adjust dosing pump, CGM glucometer downloads 15 (mean age 16.2 ± 4.3 years, six female, mean glycated haemoglobin 8.3 0.9% [66.8 7.3 mmol/mol]) gathered over a 3-week period. Recommendations compared...

10.1111/dom.13408 article EN Diabetes Obesity and Metabolism 2018-06-09

To elucidate the long-term outcomes of pituitary adenomas diagnosed in childhood and adolescence, knowledge which remains sparse.A retrospective review patients aged ≤21 years at diagnosis adenoma, attending a neuroendocrine service Liverpool, UK, between 1984-2009.There were 41 (33 female), mean age 17.3 (range 11-21) follow-up 9.6 years; 29 had prolactinomas (15 macroprolactinomas), 6 non-functioning (NFPAs), 5 Cushing's disease (CD) 1 acromegaly. All prolactinoma received dopamine...

10.1530/eje-10-0519 article EN European Journal of Endocrinology 2010-08-05

For 29 patients with schizophrenia that began after age 44, the mean ventricle-to-brain ratio was significantly higher than for 23 age-matched normal subjects but smaller Alzheimer's disease and hallucinations or delusions.

10.1176/ajp.144.9.1216 article EN American Journal of Psychiatry 1987-09-01

Abstract Context Remission rates in young people with Graves hyperthyroidism are less than 25% after 2 years of thionamide antithyroid drug (ATD). Objective We explored whether rituximab (RTX), a B-lymphocyte–depleting agent, would increase remission when administered short course ATD. Methods This was an open-label, multicenter, single-arm, phase trial (ages, 12-20 years) hyperthyroidism. An A’Hern design used to distinguish encouraging rate (40%) from unacceptable (20%). Participants...

10.1210/clinem/dgab763 article EN cc-by The Journal of Clinical Endocrinology & Metabolism 2021-10-23

TPS512 Background: Oesophagogastric adenocarcinoma (OGA) is globally prevalent and frequently advanced at presentation. Less than 50% of patients with operable OGA are cured when treated multimodality therapy. Patients in the UK OGA, FLOT prior to following surgery. However, who have circulating tumour DNA (ctDNA) their blood after surgery worse survival ctDNA negative patients. Therefore, use novel treatment approaches aiming cure this micrometastatic disease considered a rational...

10.1200/jco.2025.43.4_suppl.tps512 article EN Journal of Clinical Oncology 2025-01-27

Objective Obesity is highly prevalent among adults with acquired, structural hypothalamic damage. We aimed to determine hormonal and neuroanatomical variables associated weight gain obesity in patients following damage evaluate the impact of early instigation loss measures prevent or limit severity these patients. Design Retrospective study 110 tumours attending a specialist neuroendocrine clinic. BMI was calculated at diagnosis last follow-up clinic visit. Endocrine data, procedures,...

10.1530/eje-12-0792 article EN European Journal of Endocrinology 2013-01-05

Background: There is a concern that medical training contains insufficient emphasis on adolescent and young adult health transition. Clinicians working in diabetes endocrinology across paediatric services need to have the skills work effectively with this age group. The aim of present survey was ascertain current state trainees UK. Methods: A questionnaire assessing developed using existing formats. An online disseminated UK through Young Diabetologists Endocrinologists Forum (YDEF), British...

10.15277/bjdvd.2015.049 article EN The British Journal of Diabetes 2015-11-17

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | 1479-6848 (online)

10.1530/endoabs.36.cme6 article EN Endocrine Abstracts 2014-10-14

10.1530/endoabs.33.p88 article EN 41st Meeting of the British Society for Paediatric Endocrinology and Diabetes 2013-11-01
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