A5101511716- Viral gastroenteritis research and epidemiology
- Reproductive tract infections research
- SARS-CoV-2 and COVID-19 Research
- Bacillus and Francisella bacterial research
- Bacteriophages and microbial interactions
- Yersinia bacterium, plague, ectoparasites research
- Respiratory viral infections research
- Poxvirus research and outbreaks
- Plant tissue culture and regeneration
- Animal Virus Infections Studies
- Monoclonal and Polyclonal Antibodies Research
- Burkholderia infections and melioidosis
- Probiotics and Fermented Foods
- Streptococcal Infections and Treatments
- Neonatal and Maternal Infections
- Influenza Virus Research Studies
- Flowering Plant Growth and Cultivation
- Forensic and Genetic Research
- Phytochemical Studies and Bioactivities
- Light effects on plants
- Immune Response and Inflammation
- Galectins and Cancer Biology
- Plant Ecology and Taxonomy Studies
- Parasitic Infections and Diagnostics
- Animal health and immunology
Yunnan Academy of Agricultural Sciences
2022-2025
Yunnan University
2024
Yunnan Agricultural University
2024
Institute of Microbiology
2006-2017
Academy of Military Medical Sciences
2003-2012
China Institute of Veterinary Drug Control
2011
Czech Academy of Sciences, Institute of Microbiology
2006-2008
Lilies are economically important monocots known for their ornamental flowers, bulbs, and large genomes. The absence of genomic information has impeded evolutionary studies genome-based breeding efforts. Here, we present reference genomes Lilium sargentiae (lily, 35.66 Gb) Gloriosa superba (flame lily, 5.09 Gb). giant lily genome is shaped by recent long terminal repeat retroelements. Phylogenetic analysis reveals diverse, independent origins cultivars. Gene families involved in sucrose...
Outbreaks in humans, caused by Streptococcus suis serotype 2 (SS2), were reported 1998 and 2005 China. However, the mechanism of SS2-associated infection remains unclear. For first time, a 2-D gel approach combined with MS was used to establish comprehensive reference map for aiding our understanding pathogenicity SS2. The identification 694 out 834 processed spots revealed 373 proteins. Most identified proteins located cytoplasm involved energy metabolism, protein synthesis, cellular...
Guinea pigs were inoculated with a reovirus (ReoV) and coronavirus (SARS-CoV) isolated from SARS patients to determine their potential role in the etiology of SARS. Animals infected ReoV died between day 22 30 postinoculation (PI) while 70% animals SARS-CoV 4 7 PI. The titer neutralizing antibodies against ranged 80 160 when two viruses, respectively, was just below 10 coinfections. animal developed diffuse alveolar damage similar exudative leakage inflammation found patients, characterized...
Lilies are one of the most important ornamental flowers worldwide with approximately 100 wild species and numerous cultivars, but phylogenetic relationships among their contributions to these cultivars poorly resolved. We collected major Lilium assembled plastome sequences. Our reconstruction using 114 plastid genomes, including 70 representing all sections 42 six hybrid divisions two outgroups, uncovered well-supported genetic within . The were separated into distinct groups (groups A B)...
A total of 420 rodents in China were examined for Francisella tularensis by polymerase chain reaction. The infection rates 4.76% total, and 11.65%, 10.00%, 6.56%, 1.77%, 0% Jilin, Xinjiang, Heilongjiang, Inner Mongolia, Zhejiang, respectively. Sequence analysis showed that all the detected agents belonged to F. subsp. holarctica.
Influenza A virus causes annual epidemics and occasional pandemics in humans. Here, we investigated four members of the fibroblast growth factor receptor (FGFR) family; FGFR1 to 4, examined their expression patterns human lung epithelial cells A549 with influenza infection. We identified a functional role A/Puerto Rico/8/1934 (PR8) A/Anhui/01/2005 (H5N1) replication. Our results showed that silencing by siRNA interference promoted A/PR8 H5N1 replication cells, while lentivirus-mediated...
Abstract Twenty-one bacterial strains were isolated from imported cattle hide and rabbit wool using two types of media, nutrient broth, broth with serum. The bacteria identified Brevibacillus laterosporus, Leclercia adecarboxylata, Peptococcus niger, Bacillus circulans, Raoultella ornithinolytica, subtilis, cereus, thermobacillus, choshinensis, sphaericus, Acinetobacter haemolyticus, Sphingomonas paucimobilis, thuringiensis, Staphylococcus intermedius, Mycobacteria, Moraxella, Klebsiella...
Experimental studies were performed to determine the role of a newly isolated reovirus (ReoV) from severe acute respiratory syndrome (SARS) patient in etiology this described serious syndrome. Four cynomologus macaques inoculated with (BYD1) an attempt replicate infection and pathology observed SARS. The body temperature infected monkeys was monitored three times day, blood fecal samples periodically collected for specific immunology determinations. On days 7 33 after inoculation, necropsies...
Burkholderia pseudomallei is the etiological agent of potentially fatal disease melioidosis. Here, we report draft genome sequence a virulent water isolate obtained from Hainan Province China in 1976, B. strain 350105.
Trachoma, the leading infectious cause of blindness worldwide, is an ancient human disease. Its existence in China can be traced back to as early 27th century BC. In modern China, overall prevalence trachoma has dramatically reduced, but still endemic many areas country. Here we report that 26 (8%) 322 students from 2 rural boarding schools Qinghai province, west were identified having ocular C. trachomatis infection; and 15 strains isolated these patients. Chlamydiae 37 clinical samples...
We reported the isolation and characterization of a novel mammalian reassortant reovirus BYD1 that may have played an accomplice role with SARS-coronavirus during 2003 SARS pandemic. The pathogenic mechanism this is unknown. Reovirus pathogenicity has been associated virus-induced apoptosis in cultured cells vivo. outer capsid protein μ1 recognized as primary determinant reovirus-induced apoptosis. Here, we investigated induced by BYD1, its μ1, cell-attachment σ1 to understand pathogenesis...
<title>Abstract</title> Dahlia (<italic>Dahlia sp.</italic>), a species of the Asteraceae family, is widely cultivated in China and exhibits seasonal blooming. The main challenges associated with this are low cross-breeding efficiency slow breeding. In study, dahlia leaves petals were employed as test materials to ascertain optimal conditions for protoplast isolation, refine critical factors transient transformation, develop system purification utilisation protoplasts. best procedure...
The objective of this study was to investigate the pathogenicity and associated lesions a new reovirus (ReoV) isolated from patients with Severe Acute Respiratory Syndrome (SARS) in China. Twenty-five four-week-old BALB/c female mice inoculated intranasally either ReoV (strain BYD1) alone, or combined SARS-CoV BJF) displayed ejecting fur loss body weight compared control animals. were most postmortem tissues. histopathological features infected animals consisted diffuse alveolar damage,...
Francisella tularensis is the etiological agent of potentially fatal disease tularemia. Here, we report draft genome sequence a virulent human isolate from Tibet, China in 1962, F. strain 410108, an intermediate-genotype subsp. holarctica between biovar japonica and non-japonica strains world.