A5012379258- Asthma and respiratory diseases
- Human Health and Disease
- Digestive system and related health
- Respiratory and Cough-Related Research
- Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
- Gastroesophageal reflux and treatments
- Vitamin D Research Studies
- Medical Imaging and Pathology Studies
- Renal function and acid-base balance
- Refrigeration and Air Conditioning Technologies
- Biomarkers in Disease Mechanisms
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Healthcare Systems and Public Health
Kharkiv National Medical University
2017-2022
The increasing prevalence of asthma (A) and diabetes mellitus type 2 (DM2T) necessitates administration the adequate antiasthmatic long-term basic therapy with consideration comorbid states. purpose consisted in revealing therapeutic potential Tiotropium bromide (TB) L-arginine (Tivortine) patients having uncontrolled moderately severe combination DM2T (A+DM2T). Forty seven A+DM2T underwent an in-depth study before after their treatment. They were divided into groups: treatment (group 1,...
Abstract. Hypersensitivity pneumonitis (HP), or exogenous allergic alveolitis, is a complex and heterogeneous immune-mediated inflammatory and/or fibrotic disease of the lung parenchyma, small airways interstitium that occurs in people with congenital acquired hypersensitivity/ susceptibility to certain inhaled antigens. The can occur acute/inflammatory form (duration less than 6 months) chronic more months). According latter classification, HP divided into non-fibrotic forms: mild compared...
Yeryomenko G.V, Ospanova T.S, Khimich T.U, Bezditko T.V, Bolokadze E. O., Mizhiritskaya T.V.Patients with asthma accompanied by obesity in a higher body mass index were found to have an increased “waist/hip volume” ratio as compared patients and healthy subjects. Assessment of humoral immunity indices showed increase non-specific (with rising concentrations immunoglobulins Ig A, M, G) specific level E) immunity. Patients comorbidity shown differently directed changes the concentration main...
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Background. The acid-alkaline state (AAS) in physiological conditions is caused by a certain ratio of acids and alkalis blood plasma as well organs tissues. Imbalances the above are observed patients with asthma (As).
 Objective. To study AAS an uncontrolled course As.
 Materials methods. involved 27 having moderately severe As metabolic acidosis without any controls. Physical examinations were made; respiratory function assessed. divided into two groups: 13 cases – group 1 14 2....
The aim: Revealing of clinical-pathogenetic peculiarities in manifestations uncontrolled As+MS. Materials and methods: Sixty-five cases, divided into 2 groups: Group I – severe As (n=20), As+MS (n=45). general clinical examination included fasting blood glucose, insulin level, HOMA-IR index, body mass index (BMI), spirometry, levels ММР-9, МСР-1, IL-8 IL-12. Results: In I, 20 patients (100%) had obstructive respiratory dysfunction. II 13 cases (28.88%) with the restrictive, 15 (33.33%) 17...
Asthma (As) and metabolic disturbances are widespread socially significant states, obesity (Ob) being also one of them. The comorbidity As Ob both affects physiological mechanisms bronchial obstruction syndrome, the course prognosis these two diseases significantly complicates their treatment. A combination changes in ventilation a complex architectonics bronchi may contribute to worsening control over As. performed study deals with problem early diagnosis progression patients comorbidity....