A5019860152- Cervical and Thoracic Myelopathy
- Spine and Intervertebral Disc Pathology
- Spinal Fractures and Fixation Techniques
- Cancer Immunotherapy and Biomarkers
- Immunotherapy and Immune Responses
- Cancer Cells and Metastasis
- Innovations in Medical Education
- Meta-analysis and systematic reviews
- Health and Medical Research Impacts
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Parvovirus B19 Infection Studies
- Cardiovascular Issues in Pregnancy
- Spinal Cord Injury Research
- Spinal Hematomas and Complications
- Histiocytic Disorders and Treatments
- Stroke Rehabilitation and Recovery
- Orthopaedic implants and arthroplasty
- Peptidase Inhibition and Analysis
University of Cambridge
2022-2024
University of Oxford
2024
Addenbrooke's Hospital
2023-2024
Health Education England
2024
Lawn Tennis Association
2022
<sec> <title>BACKGROUND</title> Degenerative cervical myelopathy (DCM) is a progressive neurological condition, characterized by spinal cord injury secondary to degenerative changes in the spine. Misdiagnosis primary care forms part of complex picture leading an average diagnostic delay 2 years. This leads potentially preventable and permanent disability. A lack awareness deficits postgraduate education may contribute these delays. </sec> <title>OBJECTIVE</title> study aims assess DCM...
Background Degenerative cervical myelopathy (DCM) is a progressive neurological condition, characterized by spinal cord injury secondary to degenerative changes in the spine. Misdiagnosis primary care forms part of complex picture leading an average diagnostic delay 2 years. This leads potentially preventable and permanent disability. A lack awareness deficits postgraduate education may contribute these delays. Objective study aims assess DCM setting general practice. Methods General...
Research methodology is insufficiently featured in undergraduate medical curricula. Student-selected components are designed to offer some research opportunities but frequently fail meet student or supervisor expectations, such as completion publication. We hypothesized that a collaborative, educational approach systematic review (SR), whereby students worked together, may improve experience and increase success.This study aimed establish whether offering small team of the opportunity take...
Abstract Leucine-rich repeat-containing G-protein receptor 5 (LGR5) has been characterised as a stem cell and cancer marker. Previous analyses of LGR5 transcript levels indicate high level expression discriminates malignancies such colorectal (CRC) pre-B acute lymphoblastic leukaemia (pre-B ALL) from healthy tissues suggesting protein may provide molecular handle for prognosis treatment. We have developed highly specific, affinity antibodies to the extracellular domain human (α-LGR5) that...
Bilateral upper limb paraesthesia and pain are common symptoms of degenerative cervical myelopathy (DCM). Such instigate investigation by spine magnetic resonance imaging (MRI). This was the case for our patient, who 72-years-in age otherwise fit well. During scan he unfortunately developed sudden onset quadriplegia secondary to an intervertebral disc prolapse. necessitated intubation due respiratory failure urgent transfer neurosciences critical care unit at a tertiary centre. Despite...
We report a case of BRAF-mutation positive Erdheim-Chester disease presenting with cerebellar ataxia. This is the first such to be reported without structural MRI abnormalities but single intrathecally produced oligoclonal band. Now that histiocytoses have been recharacterised as neoplastic, we speculate mechanism ataxia in our paraneoplastic. highlight importance searching for BRAF mutations this disease, their presence leads effective personalised treatments.
<sec> <title>BACKGROUND</title> Research methodology is insufficiently featured in undergraduate medical curricula. Student-selected components are designed to offer some research opportunities but frequently fail meet student or supervisor expectations, such as completion publication. We hypothesized that a collaborative, educational approach systematic review (SR), whereby students worked together, may improve experience and increase success. </sec> <title>OBJECTIVE</title> This study...