A5004247544- Leprosy Research and Treatment
- Tryptophan and brain disorders
- Phytochemicals and Antioxidant Activities
- Natural product bioactivities and synthesis
- Health, Nursing, Elderly Care
- Essential Oils and Antimicrobial Activity
- Respiratory and Cough-Related Research
- Bioactive Compounds and Antitumor Agents
- Ion Channels and Receptors
- Tuberculosis Research and Epidemiology
- Pain Mechanisms and Treatments
- Coconut Research and Applications
- Photosynthetic Processes and Mechanisms
- Endometriosis Research and Treatment
- Menstrual Health and Disorders
- Treatment of Major Depression
- Stress Responses and Cortisol
- Protein Hydrolysis and Bioactive Peptides
- Plant-based Medicinal Research
- Microbial Metabolism and Applications
- Date Palm Research Studies
- Sleep and Wakefulness Research
- Biochemical and biochemical processes
- Phenothiazines and Benzothiazines Synthesis and Activities
- Ovarian function and disorders
Universidade Federal do Vale do São Francisco
2018-2025
LIttoral ENvironnement et Sociétés
2023-2024
Centre National de la Recherche Scientifique
2022-2024
La Rochelle Université
2022-2024
Universidade São Francisco
2018-2020
ABSTRACT Vanillin (4‐hydroxy‐3‐methoxybenzaldehyde) is a phenolic aldehyde compound found in the plants of genus Vanilla . This substance widely used as flavouring world, food even pharmaceutical industries. Some studies have reported pharmacological activities such antitumor, antinociceptive, anti‐inflammatory and neuroprotective activities. study aimed to investigate spasmolytic, antitussive, expectorant anti‐asthmatic effects vanillin rodents. The spasmolytic activity was assayed isolated...
Abstract The monoterpene alcohol (−)‐borneol has many biological effects such as sedative, anti‐inflammatory, analgesic, anti‐nociceptive, antithrombotic and vasorelaxant effects. Our objective in this study was to investigate the mechanism of action determine its effect. (−)‐Borneol tested on isolated aortic rings contracted with PE (10 −6 m ). This performed absence or presence endothelium, L‐ NAME (100 μ ), indomethacin TEA (1 10 4‐ AP ) glibenclamide assess participation EDRF , nitric...
Pain and inflammation are unpleasant experiences that usually occur as a result of tissue damage. Despite the number existing analgesic drugs, side effects limit their use, stimulating search for new therapeutic agents. In this sense, five hydrazone derivatives (H1, H2, H3, H4, H5), with general structure R 1 2 C = NNR 3 4 , were synthesized molecular modification strategies. paper, we describe ability to attenuate nociceptive behavior inflammatory response in mice. Antinociceptive activity...
Abstract Background Brazil has a high leprosy burden and poor treatment outcomes (TOs), manifesting in relapse rates. Pernambuco, an impoverished Brazilian state suffering notable geographical health inequalities, ‘ hyperendemic’ leprosy. Although current literature identifies barriers facilitators influencing compliance, inadequate investigation exists on other factors TOs, including carers’ roles psycho-dermatological impact. This qualitative study explores experiences perceptions of...
Depression is a psychiatric disorder with limited therapy options. Psychedelics are new antidepressant candidates, being the ayahuasca one of most promising ones. A synergistic combination N,N-dimethyltryptamine (DMT) and β-carbolines allows properties. Another psychedelic DMT-containing beverage jurema wine used religiously by indigenous people from Northeastern Brazil.To evaluate antidepressant-like effect standardized extract Mimosa tenuiflora (SEMT), associated or not harmine...
The study was conducted to examine the antioxidant activity and evaluate protective effects of date seeds powder kentichi against alloxan-induced damage in liver, kidney, pancreas diabetic's rats. Group 1: control group, that did not receive any treatment, 2: alloxan injected intraperitoneally (120 mg/kg body weight) for two days (Diab), 3: treated only by added diet (300 g/kg) 6 weeks (DSPK), 4: alloxan-diabetic rats with (DSPK + Diab). Estimations biochemical parameters blood were...
Brown seaweeds of the Fucus genus represent a rich source natural antiviral products. In this study, ceranoides hydroalcoholic extract (FCHE) was found to inhibit 74.2 ± 1.3% proteolytic activity free SARS-CoV-2 3CL protease (3CLpro), an enzyme that plays pivotal role in polyprotein processing during coronavirus replication and has been identified as relevant drug discovery target for SARS- MERS-CoVs infections. To purify identify 3CLpro ligands with potential inhibitory using one-step...
Abstract Background Brazil has a high leprosy burden and poor treatment outcomes (TOs). Pernambuco, an impoverished Brazilian state suffering from notable geographical health inequalities, ‘ hyperendemic ’ leprosy. Although current literature identifies the barriers facilitators influencing compliance, there is inadequate investigation into other factors TOs, including carers’ roles. This qualitative study explores experiences, perceptions beliefs of patients their carers in Brazil; to...