A5068833493- Nanoparticle-Based Drug Delivery
- Nanoplatforms for cancer theranostics
- Immune cells in cancer
- Advanced Drug Delivery Systems
- RNA Interference and Gene Delivery
- Gas Sensing Nanomaterials and Sensors
- Peptidase Inhibition and Analysis
- Electrochemical Analysis and Applications
- Mass Spectrometry Techniques and Applications
- Zebrafish Biomedical Research Applications
- Pickering emulsions and particle stabilization
- Analytical chemistry methods development
- biodegradable polymer synthesis and properties
- Lipid Membrane Structure and Behavior
- Immunotherapy and Immune Responses
- Characterization and Applications of Magnetic Nanoparticles
- Glycosylation and Glycoproteins Research
- ZnO doping and properties
- Advanced Photocatalysis Techniques
Universidade de Santiago de Compostela
2009-2022
Center for Research in Molecular Medicine and Chronic Diseases
2016-2018
To assess the capacity of a new drug delivery nanocapsule (NC) with double shell hyaluronic acid and protamine to overcome biological barriers using zebrafish model.NCs were prepared by solvent displacement method, tagged fluorescent makers physicochemically characterized. Toxicity was evaluated according Fish Embryo Acute test, permeability tested exposing zebrafish, without chorion, NCs.Toxicity NCs very low as compared that control nanoemulsion. Double-shell able cross chorion skin.Beyond...
Abstract Tumor-associated macrophages (TAMs), a class of immune cells that play key role in tumor immunosuppression, are recognized as important targets to improve cancer prognosis and treatment. Consequently, the engineering drug delivery nanocarriers can reach TAMs has acquired special relevance. This work describes development biological evaluation panel hyaluronic acid (HA) nanocapsules (NCs), with different compositions prepared by techniques, designed target macrophages. The results...
Abstract Magnetic nanoparticles are versatile materials that have boosted the development of different biomedical applications, being superparamagnetic magnetite a milestone in field, after achieving clinical approval as contrast agents magnetic resonance imaging (Feridex ® ), hyperthermia for oncological treatments (NanoTherm or iron deficiency supplement (Feraheme ). However, its potential theragnostic agent could be further expanded by encapsulation within biodegradable hydrogel, capable...
Abstract Water pollution affects all living habitats, since it is the most basic element that sustains life forms and, as an exceptional solvent, readily makes any compound available for cells, either nutrients or noxious substances. Elimination of molecular contaminants from water quality one challenging technical problems conventional treatments like flocculation and filtration fail short to defeat. Particulate photocatalysts, used degrade contaminants, have main drawback their recovery...
Abstract Tumor-associated macrophages (TAMs), a class of immune cells that play key role in tumor immunosuppression, are recognized as important targets to improve cancer prognosis and treatment. Consequently, the engineering drug delivery nanocarriers can reach TAMs has acquired special relevance. This work describes development biological evaluation panel hyaluronic acid (HA) nanocapsules (NCs), with different compositions prepared by techniques, designed target macrophages. The results...