About
Contact & Profiles
A5092758876
Research Areas
- Ion channel regulation and function
- Ion Channels and Receptors
- Nicotinic Acetylcholine Receptors Study
New York University Abu Dhabi
2023
Oral cancer causes pain associated with progression. We report here that the function of Ca2+ channel ORAI1 is an important regulator oral pain. was highly expressed in tumor samples from patients cancer, and activation caused sustained influx human cells. RNA-seq analysis showed regulated many genes encoding markers such as metalloproteases (MMPs) modulators. Compared control cells, cells lacking formed smaller tumors elicited decreased allodynia when inoculated into mouse paws. Exposure...
10.1126/scisignal.adf9535
article
EN
Science Signaling
2023-09-05
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