Haotian Wu

ORCID: 0000-0003-1853-0264
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About
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Research Areas
  • Cancer-related molecular mechanisms research
  • Cellular Mechanics and Interactions
  • Cancer Cells and Metastasis
  • RNA modifications and cancer
  • Cancer Immunotherapy and Biomarkers
  • Medical Imaging Techniques and Applications
  • Cancer, Hypoxia, and Metabolism
  • Ubiquitin and proteasome pathways
  • Caveolin-1 and cellular processes
  • Cancer Research and Treatments
  • Heat shock proteins research
  • Radiomics and Machine Learning in Medical Imaging
  • Advanced Radiotherapy Techniques
  • Cancer Diagnosis and Treatment
  • Prostate Cancer Treatment and Research
  • MicroRNA in disease regulation
  • Renal cell carcinoma treatment
  • Clusterin in disease pathology
  • Kruppel-like factors research
  • Mechanisms of cancer metastasis
  • Microtubule and mitosis dynamics
  • Autophagy in Disease and Therapy
  • Bladder and Urothelial Cancer Treatments
  • Telomeres, Telomerase, and Senescence

Dalian Medical University
2009-2024

First Affiliated Hospital of Dalian Medical University
2009-2024

Nanjing University of Chinese Medicine
2016

Adaptation to hypoxia is an important process physiologically and pathologically. Hypoxia-inducible factor-1α (HIF-1α) participates in the cancer biology of numerous endocrine tumors, including their proliferation differentiation. In present study, hypothesis that HIF-1α promotes tumorigenesis thyroid via upregulating angiogenesis-associated markers investigated. Reverse transcription-quantitative polymerase chain reaction (RT-qPCR) western blot analysis were used examine expression cell...

10.3892/etm.2016.3826 article EN Experimental and Therapeutic Medicine 2016-10-20

Abstract Purpose Anatomical and other changes during radiotherapy will cause inaccuracy of dose distributions, therefore the expectation for online adaptive radiation therapy (ART) is high in effectively reducing uncertainties due to intra‐variation. However, ART requires extensive time effort. This study investigated an assessment workflow based on fractional cone‐beam computed tomography (CBCT) images. Methods Image registration, synthetic CT (sCT) generation, auto‐segmentation,...

10.1002/acm2.14462 article EN cc-by Journal of Applied Clinical Medical Physics 2024-07-27

Telomerase activity is responsible for telomere maintenance and believed to be crucial in most cancer cells, but its significance gastric remains unknown. This observational study investigated whether there a relationship between telomerase the development of cancer, peritoneal dissemination. was measured primary cancers washings from same patients, findings were compared with those conventional cytology an immunoassay antigen 125 (CA125). Positive cytological examination both correlated...

10.1177/147323000903700417 article EN Journal of International Medical Research 2009-08-01

Background. The most common site of prostate cancer metastasis is bone tissue with many recent studies having conducted genomic and clinical research regarding metastatic cancer. However, further work needed to better define those patients that are at an elevated risk such metastasis. Methods. SEER TCGA databases were searched develop a nomogram for predicting Results. Herein, we leveraged the Surveillance, Epidemiology, End Results (SEER) database construct predictive capable readily...

10.1155/2022/8213723 article EN cc-by Genetics Research 2022-09-29
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