A5057275312- Genetic diversity and population structure
- Aquatic Invertebrate Ecology and Behavior
- Marine Bivalve and Aquaculture Studies
- Identification and Quantification in Food
- Genomics and Phylogenetic Studies
- Evolution and Genetic Dynamics
- Marine Biology and Ecology Research
- Marine Ecology and Invasive Species
- Genetic and phenotypic traits in livestock
- Biological Research and Disease Studies
- Aquaculture Nutrition and Growth
- Fish Ecology and Management Studies
- Environmental DNA in Biodiversity Studies
- Parasite Biology and Host Interactions
- RNA and protein synthesis mechanisms
- Genetic Mapping and Diversity in Plants and Animals
- Aquatic life and conservation
- Animal Genetics and Reproduction
- Species Distribution and Climate Change
- Marine Biology and Environmental Chemistry
- Fish Biology and Ecology Studies
- Marine and coastal plant biology
- RNA modifications and cancer
- Chromosomal and Genetic Variations
- Coral and Marine Ecosystems Studies
Université de Montpellier
2016-2025
Institut de Recherche pour le Développement
2016-2025
Centre National de la Recherche Scientifique
2016-2025
Institut des Sciences de l'Evolution de Montpellier
2016-2025
École Pratique des Hautes Études
2015-2024
University of Cambridge
2018
University of Toronto
2018
University of Sheffield
2018
Australian National University
2018
University of St Andrews
2018
Speciation results from the progressive accumulation of mutations that decrease probability mating between parental populations or reduce fitness hybrids—the so-called species barriers. The speciation genomic literature, however, is mainly a collection case studies, each with its own approach and specificities, such global view gradual process evolution one to two currently lacking. Of primary importance prevalence gene flow diverging entities, which central in most concepts has been widely...
The European sea bass (Dicentrarchus labrax) is a temperate-zone euryhaline teleost of prime importance for aquaculture and fisheries. This species subdivided into two naturally hybridizing lineages, one inhabiting the north-eastern Atlantic Ocean other Mediterranean Black seas. Here we provide high-quality chromosome-scale assembly its genome that shows high degree synteny with more highly derived teleosts. We find expansions gene families specifically associated ion water regulation,...
Owing to the remarkable progress of molecular techniques, heterozygosity-fitness correlations (HFCs) have become a popular tool study impact inbreeding in natural populations. However, their underlying mechanisms are often hotly debated. Here we argue that these “debates” rely on verbal arguments with no basis existing theory and inappropriate statistical testing, it is time reconcile HFC its historical theoretical fundaments. We show available data quantitatively qualitatively consistent...
The proportion of amino acid substitutions driven by adaptive evolution can potentially be estimated from polymorphism and divergence data an extension the McDonald-Kreitman test. We have developed a maximum-likelihood method to do this applied our several sets three Drosophila species: D. melanogaster, simulans, yakuba. number per codon is not uniformly distributed among genes, but follows leptokurtic distribution. However, fixed seems remarkably constant across genome (i.e., that are...
Hybrid zones are fascinating systems to investigate the structure of genetic barriers. Marine hybrid deserve more investigation because generally high dispersion potential planktonic larvae which allows migration on scales unrivalled by terrestrial species. Here we analyse mosaic zone between marine mussels Mytilus edulis and M. galloprovincialis, using three length-polymorphic PCR loci as neutral diagnostic markers 32 samples along Atlantic coast Europe. Instead a single gradient from...
Abstract This paper reports new experimental evidence on the effect of inbreeding growth and survival in early developmental phase a marine bivalve, flat oyster Ostrea edulis. Two crosses between full sibs were analyzed using four microsatellite markers. Samples 96 individuals taken just after spawning (day 1), at end larval stage before metamorphosis 10) postlarval 70). Significant departure from Mendelian expectation was observed two loci first cross second. Departure 1:1 segregation...
In animals, the population genomic literature is dominated by two taxa, namely mammals and drosophilids, in which fully sequenced, well-annotated genomes have been available for years. Data from other metazoan phyla are scarce, probably because vast majority of living species still lack a closely related reference genome. Here we achieve de novo, reference-free analysis wild samples five non-model animal species, based on next-generation sequencing transcriptome data. We introduce pipe-line...
Inferring a realistic demographic model from genetic data is an important challenge to gain insights into the historical events during speciation process and detect molecular signatures of selection along genomes. Recent advances in divergence population genetics have reported that face gene flow occurred more frequently than theoretically expected, but approaches used did not account for genome-wide heterogeneity (GWH) introgression rates. Here, we investigate impact GWH on inference with...
Abstract When incompletely isolated taxa coexist in a patchy environment (e.g. mosaic hybrid zones, host-race complexes), patterns of variation may differ between selected traits/genes and neutral markers. While the genetic structure traits/loci tends to coincide with habitat variables (producing Genetic-Environment Association or GEA), differentiation at loci unlinked any locus rather depends on geographic connectivity large scale Isolation-By-Distance IBD), although these often display GEA...
Selection on codon usage bias is well documented in a number of microorganisms. Whether also generally shaped by natural selection large organisms, despite their relatively small effective population size (Ne), unclear. In animals, the genetics has only been studied handful model organisms so far, and can be affected confounding, nonadaptive processes such as GC-biased gene conversion experimental artefacts. Using transcriptomics data, we analyzed relationship between usage, expression,...
Abstract Speciation is a complex process that leads to the progressive establishment of reproductive isolation barriers between diverging populations. Genome-wide comparisons closely related species have revealed existence heterogeneous divergence patterns, dominated by genomic islands increased supposed contain loci. However, this landscape only provides static picture dynamic speciation, during which confounding mechanisms unrelated speciation can interfere. Here we use haplotype-resolved...
Structured populations, and replicated zones of contact between species, are an ideal opportunity to study regions the genome with unusual levels differentiation; these can illuminate genomic architecture species isolation, spread adaptive alleles across ranges. Here, we investigated effects gene flow on divergence adaptation in Mytilus complex including parental populations quite distant geographical locations. We used target enrichment sequencing 1269 contigs a few kb each, some genes...
Transmissible cancers, in which cancer cells themselves act as an infectious agent, have been identified Tasmanian devils, dogs, and four bivalves. We investigated a disseminated neoplasia affecting geographically distant populations of two species mussels (Mytilus chilensis South America M. edulis Europe). Sequencing alleles from loci (two nuclear mitochondrial) provided evidence transmissible both species. Phylogenetic analysis cancer-associated diagnostic SNPs showed that cancers likely...
We present DILS, a deployable statistical analysis platform for conducting demographic inferences with linked selection from population genomic data using an Approximate Bayesian Computation framework. DILS takes as input single-population or two-population sets (multilocus fasta sequences) and performs three types of analyses in hierarchical manner, identifying: (a) the best model to study importance gene flow size change on genetic patterns polymorphism divergence, (b) determine whether...
Inter-individual transmission of cancer cells represents a unique form microparasites increasingly reported in marine bivalves. In this study, we sought to understand the ecology propagation Mytilus trossulus Bivalve Transmissible Neoplasia 2 (MtrBTN2), transmissible affecting four mussel species worldwide. We investigated prevalence MtrBTN2 mosaic hybrid zone M. edulis and galloprovincialis along French Atlantic coast, sampling contrasting natural anthropogenic habitats. observed similar...
Abstract Chromosomal inversions can play an important role in divergence and reproductive isolation by building maintaining distinct allelic combinations between evolutionary lineages. Alternatively, they take the form of balanced polymorphisms that segregate within populations until one arrangement becomes fixed. Many questions remain about how inversion arise, are maintained over long term, ultimately, whether contribute to speciation. The long‐snouted seahorse ( Hippocampus guttulatus )...
Abstract How the interplay of biotic and abiotic factors shapes current genetic diversity at community level remains an open question, particularly in deep sea. Comparative phylogeography multiple species can reveal influence past climatic events, geographic barriers, life history traits on spatial patterns structure across lineages. To shed light that shape community-level variation to improve our understanding deep-sea biogeographic patterns, we conducted a comparative population genomics...
Marine organisms challenge the classical theories of local adaptation and speciation because their planktonic larvae have potential to maintain high gene flow. The marine–speciation paradox is illustrated by contact zones between incipient species that are so large allopatric divergence seems unlikely. For this reason any mechanism preventing sympatric two from coexisting in same habitats can be a powerful promoter speciation. zone hybridizing taxa mussel, Mytilus edulis M....