- Quantum Computing Algorithms and Architecture
- Quantum Information and Cryptography
- Advanced NMR Techniques and Applications
- Quantum Mechanics and Applications
- NMR spectroscopy and applications
- Quantum and electron transport phenomena
- Molecular spectroscopy and chirality
- Protein Structure and Dynamics
- Atomic and Subatomic Physics Research
- Spectroscopy and Quantum Chemical Studies
- Quantum optics and atomic interactions
- Advanced MRI Techniques and Applications
- Enzyme Structure and Function
- Quantum-Dot Cellular Automata
- Cold Atom Physics and Bose-Einstein Condensates
- French Urban and Social Studies
- Laser-Matter Interactions and Applications
- Quantum many-body systems
- Nuclear Physics and Applications
- Nuclear physics research studies
- Molecular Junctions and Nanostructures
- Prion Diseases and Protein Misfolding
- Quantum chaos and dynamical systems
- RNA and protein synthesis mechanisms
- Mass Spectrometry Techniques and Applications
University of Oxford
2012-2024
Swansea University
1968-2024
University of Georgia
2021
Union Hospital
2021
University of Portsmouth
2019
University of Bristol
2013
University of Liverpool
2008
International Centre for Genetic Engineering and Biotechnology
2003
University of Pavia
2003
Lawrence Livermore National Laboratory
2003
Pulse field gradient NMR methods have been used to determine the effective hydrodynamic radii of a range native and nonnative protein conformations. From these experimental data, empirical relationships between measured radius (Rh) number residues in polypeptide chain (N) established; for folded proteins Rh = 4.75N 0.29Å highly denatured states 2.21N 0.57Å. Predictions from equations agree well with data dynamic light scattering small-angle X-ray or neutron studies reported literature...
The SH3 domain is a well characterized small protein module with simple fold found in many proteins. At acid pH, the (PI3-SH3) of p85α subunit bovine phosphatidylinositol 3-kinase slowly forms gel that consists typical amyloid fibrils as assessed by electron microscopy, Congo red binding assay, and x-ray fiber diffraction. soluble form PI3-SH3 at pH (the A state variety techniques) from which are generated has been characterized. Circular dichroism far- near-UV regions 1 H NMR indicate...
Quantum-Enhanced Measurement The single electron spin in a molecule, atom, or quantum dot precesses magnetic field and so can be used as sensor. As the number of spins sensor increases, too does sensitivity. Quantum mechanical entanglement ensemble should then allow sensitivity to increase much more than would expected from simple individual ensemble. Using highly symmetric trimethyl phosphite, molecule containing central P atom surrounded by nine hydrogen atoms, Jones et al. (p. 1166 ,...
Oxidized and reduced hen lysozyme denatured in 8 M urea at low pH have been studied detail by NMR methods. 15N correlated NOESY TOCSY experiments provided near complete sequential assignment for both 1H resonances. Over 900 NOEs, including 130 (i, i + 2) 23 3) could be identified analysis of the spectra states, 3J(HN, Hα) coupling constants relaxation rates measured. The constant NOE data were analyzed comparisons with theoretical predictions from a random coil polypeptide model based on...
Quantum computing shows great promise for the solution of many difficult problems, such as simulation quantum systems and factorization large numbers. While theory is fairly well understood, it has proved to implement computers in real physical systems. It recently been shown that nuclear magnetic resonance (NMR) can be used small using spin states nuclei carefully chosen molecules. Here we demonstrate use a NMR computer based on pyrimidine base cytosine, implementation algorithm solve...
We describe in detail a general strategy for implementing conditional geometric phase between two spins. Combined with single-spin operations, this simple operation is universal gate quantum computation, that any unitary transformation can be implemented arbitrary precision using only operations and shifts. Thus geometrical phases form the basis of computation. Moreover, as induced depends on geometry paths executed by spins it resilient to certain types errors offers potential naturally...
We describe the use of composite rotations to combat systematic errors in single-qubit quantum logic gates and discuss three families which can be used correct off-resonance pulse length errors. Although developed described within context nuclear magnetic resonance computing, these sequences should applicable any implementation computation.
Abstract In ordinary, non-relativistic, quantum physics, time enters only as a parameter and not an observable: state of physical system is specified at given then evolved according to the prescribed dynamics. While can usually does, extend across all space, it defined one instant time. Here we ask what would happen if notion density matrix for multiple spatial temporal measurements. We introduce concept pseudo-density (PDM) which treats space indiscriminately. This in general fails be...
Polar molecules are an emerging platform for quantum technologies based on their long-range electric dipole--dipole interactions, which open new possibilities information processing and the simulation of strongly correlated systems. Here, we use magnetic microwave fields to design a fast entangling gate with $>0.999$ fidelity is robust respect fluctuations in trapping control small thermal excitations. These results establish feasibility build scalable processor broad range molecular species...
Here we describe a nuclear magnetic resonance (NMR) experiment that uses three qubit NMR device to implement the one-to-two approximate quantum cloning network of Buzek et al. [Phys. Rev. A 56, 3446 (1997)]. As expected experimental results indicate clones all input states with similar fidelities, but as result decoherence and incoherent evolution arising from B(1) inhomogeneity total fidelity achieved does not exceed measurement bound.
We describe the development and application of a novel rapid sample-mixing technique for real-time NMR (nuclear magnetic resonance) spectroscopy. The apparatus consists an insert inside conventional tube coupled to injection syringe outside magnet. Efficient homogeneous mixing solutions in is achieved with dead time tens milliseconds, without modification probe or additional hardware Provision made inclusion optical fiber allow situ laser irradiation samples, example generate photo-CIDNP...
Measurement devices could benefit from entangled correlations to yield a measurement sensitivity approaching the physical Heisenberg limit. Building upon previous magnetometric work using pseudoentangled spin states in solution-state NMR, we present two conceptual advancements better prepare and interpret pseudoentanglement resource. We apply these 13-spin cat state measure local magnetic field with 12.2 increase over an equivalent number of isolated spins.
Atom interferometric sensors and quantum information processors must maintain coherence while the evolving wavefunction is split, transformed recombined, but suffer from experimental inhomogeneities uncertainties in speeds paths of these operations. Several error-correction techniques have been proposed to isolate variable interest. Here we apply composite pulse methods velocity-sensitive Raman state manipulation a freely-expanding thermal atom cloud. We compare several established...
CdSe1–xTex quantum dot (QD) alloys are characterized by high luminescence yields and a strong band gap bowing as function of the Se:Te ratio, featuring longer emission wavelengths than CdTe or CdSe dots identical size. In this contribution, these properties rationalized examining structure edge energy functions x. The QDs were synthesized employing "hot-injection" method, in presence either trioctylphosphine oxide (TOPO) octadecene (ODE) Cd precursor solvent. Elementary analysis indicated...