A5026447926- Advanced NMR Techniques and Applications
- Electron Spin Resonance Studies
- NMR spectroscopy and applications
- Advanced MRI Techniques and Applications
- Quantum Information and Cryptography
- Quantum Computing Algorithms and Architecture
- Spectroscopy and Quantum Chemical Studies
- Molecular spectroscopy and chirality
- Solid-state spectroscopy and crystallography
- Atomic and Subatomic Physics Research
- Laser-Matter Interactions and Applications
- Quantum chaos and dynamical systems
- Quantum and electron transport phenomena
- Quantum optics and atomic interactions
- Lanthanide and Transition Metal Complexes
- Protein Structure and Dynamics
- Quantum Mechanics and Applications
- DNA and Nucleic Acid Chemistry
- Ultrasound Imaging and Elastography
- Quantum many-body systems
- Quantum-Dot Cellular Automata
- Advanced Fiber Laser Technologies
- MRI in cancer diagnosis
- Microbial Natural Products and Biosynthesis
- RNA and protein synthesis mechanisms
Technical University of Munich
2015-2024
Munich Center for Quantum Science and Technology
2019-2024
Helmholtz Zentrum München
2014
Wright State University
2002-2014
Umeå University
2012
Chemie³ (Germany)
2012
Goethe University Frankfurt
1992-2007
Center for NanoScience
2005
Aarhus University
1998-2004
Harvard University
2002-2004
In this paper, we study the design of pulse sequences for NMR spectroscopy as a problem time optimal control unitary propagator. Radio frequency pulses are used in coherent to implement transfer state. Pulse that accomplish desired should be short possible order minimize effects relaxation and optimize sensitivity experiments. Here, give an analytical characterization such applicable coherence experiments multiple-spin systems. We have adopted general mathematical formulation, present many...
It is control that turns scientific knowledge into useful technology: in physics and engineering it provides a systematic way for driving dynamical system from given initial state desired target with minimized expenditure of energy resources. As one the cornerstones enabling quantum technologies, optimal keeps evolving expanding areas as diverse quantum-enhanced sensing, manipulation single spins, photons, or atoms, optical spectroscopy, photochemistry, magnetic resonance (spectroscopy well...
Within the last two decades, Quantum Technologies (QT) have made tremendous progress, moving from Noble Prize award-winning experiments on quantum physics into a cross-disciplinary field of applied research. are being developed now that explicitly address individual states and make use 'strange' properties, such as superposition entanglement. The comprises four domains: Communication, Simulation, Computation, Sensing Metrology. One success factor for rapid advancement QT is well-aligned...
Abstract Quantum optimal control, a toolbox for devising and implementing the shapes of external fields that accomplish given tasks in operation quantum device best way possible, has evolved into one cornerstones enabling technologies. The last few years have seen rapid evolution expansion field. We review here recent progress our understanding controllability open systems development application control techniques to also address key challenges sketch roadmap future developments.
For paving the way to novel applications in quantum simulation, computation, and technology, increasingly large systems have be steered with high precision. It is a typical task amenable numerical optimal control turn time course of pulses, i.e. piecewise constant amplitudes, iteratively into an optimised shape. Here, we present first comparative study algorithms for wide range finite-dimensional applications. We focus on most commonly used algorithms: GRAPE methods which update all controls...
Oxidized and reduced hen lysozyme denatured in 8 M urea at low pH have been studied detail by NMR methods. 15N correlated NOESY TOCSY experiments provided near complete sequential assignment for both 1H resonances. Over 900 NOEs, including 130 (i, i + 2) 23 3) could be identified analysis of the spectra states, 3J(HN, Hα) coupling constants relaxation rates measured. The constant NOE data were analyzed comparisons with theoretical predictions from a random coil polypeptide model based on...
Radio-frequency pulses are used in nuclear-magnetic-resonance spectroscopy to produce unitary transfer of states. Pulse sequences that accomplish a desired should be as short possible order minimize the effects relaxation, and optimize sensitivity experiments. Many coherence-transfer experiments NMR, involving network coupled spins, use temporary spin decoupling effective Hamiltonians. In this paper, we demonstrate significant time can saved producing an Hamiltonian if is avoided. We provide...
Experiments in coherent magnetic resonance, microwave, and optical spectroscopy control quantum-mechanical ensembles by guiding them from initial states toward target unitary transformation. Often, the coherences detected as signals are represented a non-Hermitian operator. Hence, spectroscopic experiments, such those used nuclear correspond to transformations between operators that general not Hermitian. A gradient-based systematic procedure for optimizing these is described finds largest...
We consider the time-optimal control by magnetic fields of a spin $\frac{1}{2}$ particle in dissipative environment. This system is used as an illustrative example to show role singular extremals quantum systems. analyze simple case where law explicitly determined. experimentally implement optimal using techniques nuclear resonance. To our knowledge, this first experimental demonstration systems with bounded amplitudes.
Abstract Metabolic imaging with hyperpolarized [1‐ 13 C]pyruvate offers the unique opportunity for a minimally invasive detection of cellular metabolism. Efficient and robust acquisition reconstruction techniques are required capturing wealth information present limited duration state (∼1 min). In this study, Dixon/IDEAL type water–fat separation is expanded toward spectroscopic its down‐stream metabolites. For purpose, spectral–spatial encoding based on single‐shot spiral image echo‐time...
Distance and spins: A new broadband, frequency-selective inversion pulse has been devised for pulsed electron–electron double resonance (PELDOR) spectroscopy, a unique method used to determine distance distributions between two or more paramagnetic centers 2–10 nm apart. The PELDOR modulation depth can be increased by substituting the rectangular pump shaped pulse. As service our authors readers, this journal provides supporting information supplied authors. Such materials are peer reviewed...
Abstract Natural pH regulatory mechanisms can be overruled during several pathologies such as cancer, inflammation and ischaemia, leading to local changes in the human body. Here we demonstrate that 13 C-labelled zymonic acid (ZA) used hyperpolarized magnetic resonance imaging sensor. ZA is synthesized from [1- C]pyruvic its C frequencies shift up 3.0 p.p.m. per unit physiological range. The long lifetime of signal enhancement enables monitoring pH, independent concentration, temperature,...
The ability to live in coherent superpositions is a signature trait of quantum systems and constitutes an irreplaceable resource for quantum-enhanced technologies. However, decoherence effects usually destroy superpositions. It was recently predicted that, composite system exposed dephasing noise, coherence transversal reference basis can stay protected indefinite time. This occur class states independently the measure used quantify coherence, it requires no control on during dynamics. Here,...
In this paper, we demonstrate how optimal control methods can be used to speed up the implementation of modules quantum algorithms or simulations in networks coupled qubits. The gain is most prominent realistic cases, where qubits are not all mutually coupled. Thus shortest times obtained depend on coupling topology as well characteristic ratio time scales for local controls vs nonlocal (i.e., coupling) evolutions specific experimental setting. Relating these minimal number gives tightest...