A5081492617- Prenatal Substance Exposure Effects
- Birth, Development, and Health
- Homelessness and Social Issues
- Gestational Diabetes Research and Management
- Substance Abuse Treatment and Outcomes
- Epigenetics and DNA Methylation
- Community Health and Development
- Indigenous Health, Education, and Rights
- Mental Health Research Topics
- Child Abuse and Trauma
- Alcohol Consumption and Health Effects
- Artificial Intelligence in Healthcare
- Opioid Use Disorder Treatment
- Infant Development and Preterm Care
- Maternal Mental Health During Pregnancy and Postpartum
- Microbial infections and disease research
- Blood Pressure and Hypertension Studies
- Erythrocyte Function and Pathophysiology
- Pharmaceutical Practices and Patient Outcomes
- Enzyme Production and Characterization
- Health Policy Implementation Science
- Blood groups and transfusion
- Coronary Artery Anomalies
- Phytase and its Applications
- Language Development and Disorders
The University of Western Australia
2016-2024
The Kids Research Institute Australia
2016-2024
Curtin University
2021-2023
National Health and Medical Research Council
2018-2022
Princess Margaret Hospital for Children
2021
The University of Queensland
1991-2020
Princess Alexandra Hospital
2007-2020
Royal Brisbane and Women's Hospital
2019
Google (United States)
2018
Queensland Health
2012-2013
The three sinuses of Valsalva are best described as right, left, and posterior, the last being non-coronary sinus.An aneurysm may develop in relation to any these, but right sinus is one most usually involved; then generally ruptures into ventricle.The posterior far less often implicated.It comes close anatomical relationship atrium, which an this likely rupture.
Individuals with Fetal Alcohol Spectrum Disorder (FASD) are at risk of having adverse childhood experiences (ACEs), especially those child protection and/or justice system involvement. The complex relationship between FASD and psychosocial vulnerabilities in the affected individual is an important clinical factor for comorbidity. This study (1) explored ACEs associated stressors individuals FASD; (2) investigated association negative outcomes, i.e., justice/child involvement; (3) examined...
Executive functioning and self-regulation influence a range of outcomes across the life course including physical mental health, educational success, employment. Children prenatally exposed to alcohol or early trauma (ELT) are at higher risk impairment these skills may require intervention address deficits. Researchers partnered with local Aboriginal health organization schools develop pilot manualized version Alert Program® in Fitzroy Valley, north Western Australia, region documented high...
With few exceptions, research in the addictive sciences has relied on linear statistics and methodologies. Addiction involves a complex array of nonlinear behaviors. This study applies two machine learning techniques, Bayesian decision tree classifiers, assessment outcome an alcohol dependence treatment program. These approaches are compared to standard analysis. Seventy-three alcohol-dependent subjects undertaking 12-week cognitive-behavioral therapy (CBT) program 66 identical but also...
Clinical staff are typically poor at predicting alcohol dependence treatment outcomes. Machine learning (ML) offers the potential to model complex clinical data more effectively. This study tested predictive accuracy of ML algorithms demonstrated be effective in outcomes, compared with judgement and traditional linear regression.Prospective study. models were trained on 1016 previously treated patients (training-set) who attended a hospital-based drug clinic. (n = 27), psychologists 10)...
Introduction While research highlights the benefits of early diagnosis and intervention for children with fetal alcohol spectrum disorders (FASD), there are limited data documenting effective interventions Australian living in remote communities. Methods analysis This self-controlled cluster randomised trial is evaluating effectiveness an 8-week Alert Program school curriculum improving self-regulation executive function Aboriginal Children grades 1–6 attending any eight participating...
Although previous research has demonstrated the benefits of targeting self-regulation in non-Aboriginal children, it is unclear whether such programs would be effective for Aboriginal children attending school remote communities. Some these have been diagnosed with a fetal alcohol spectrum disorder (FASD) impairing their ability to self-regulate. The aim this article describe three phase formative process develop and pilot curriculum version Alert Program® , promising intervention improving...
A detailed study of the canine blood group system was undertaken, resulting in expansion this into a three-factor, four-allelic one with recognition an additional subtype, a3. The serological and extensive family data supported proposed genetic theory four alleles dominance order being Aa1, Aa2, Aa3 A-. Gene frequencies were determined various breeds dogs general Brisbane population 0.244 (Aa1), 0.042 (Aa2), 0.045 (Aa3) 0.669 (A-).
Self-regulation and executive functioning impairments are common in children with fetal alcohol spectrum disorder. Given the high rates of disorder identified amongst living remote Fitzroy Valley region Western Australia, Alert Program® was as a culturally safe intervention for use local primary schools. Researchers collaborated Aboriginal Elders, community members, staff from school to trial Program®. Teachers were trained deliver eight lessons class. measured using teacher parent/caregiver...
Aboriginal leaders in remote Western Australian communities with high rates of prenatal alcohol exposure invited researchers to evaluate the community-led Marulu foetal spectrum disorder (FASD) Prevention Strategy initiated 2010. The proportion women reporting use during pregnancy midwives was compared between 2008, 2010 and 2015. Initial midwife appointments were calculated by weeks gestation. proportions age at birth compared. Alcohol reduced significantly from (61.0%) 2015 (31.9%)...
IntroductionFetal Alcohol Spectrum Disorder (FASD) is a neurodevelopmental disorder caused by prenatal alcoholexposure (PAE). FASD research rapidly growing field that crosses multiple disciplines. To ensureresearch relevant and meaningful for people living with FASD, their families, the broader publicthere need to engage community members in setting priorities research.
 ObjectivesOur primary objective was formally identify views of par-ents/caregivers, service providers, general on...
Alcohol consumption in pregnancy can affect genome regulation the developing offspring but results have been contradictory. We employed a physiologically relevant murine model of short-term moderate prenatal alcohol exposure (PAE) resembling common patterns humans. Early PAE was sufficient to site-specific DNA methylation newborn pups without altering behavioural outcomes adult littermates. Whole-genome bisulfite sequencing neonatal brain and liver revealed stochastic influence on that...
Twenty blood typing reagents, four agglutinins and 16 operable in the antiglobulin test, were prepared from 54 antisera which produced 24 dogs. Two of reagents identified as anti-B Nf6. antigens shown by absorption family studies to be linear subtypes. In most cases, detailed demonstrated a Mendelian dominant inheritance for genes controlling canine red cell antigens. Gene frequencies determined various breeds dogs dingo.
The current study aimed to compare traditional logistic regression models with machine learning algorithms investigate the predictive ability of (a) communication performance at 3 years old on language outcomes 10 and (b) broader developmental skills (motor, social, adaptive) old.Participants (N = 1,322) were drawn from Western Australian Pregnancy Cohort (Raine) Study (Straker et al., 2017). A general screener, Infant Monitoring Questionnaire (Squires, Bricker, & Potter, 1990), was...
Studies in north-western Australia Aboriginal communities identified executive functioning and behavioural regulation as significant issues for children. Exposure to alcohol prenatally adverse childhood experiences are known risk factors impaired self-regulation function, these being present remote communities. In response, a partnership was initiated trial teacher-delivered intervention based on the Alert Program®. While student outcomes were assessed, this paper describes implementation...
Neurodevelopmental impairments resulting from Foetal Alcohol Spectrum Disorder (FASD) can increase the likelihood of justice system involvement. This study compared offence characteristics in young people with FASD to demographically matched controls (n = 500) Western Australia. A novel approach (i.e. association rule mining) was adopted uncover relationships between personal attributes and characteristics. For participants 100), file records were reviewed retrospectively. Mean age total...