An essential component of the human diet, L-tryptophan is critical in a number metabolic functions and has been widely used numerous research clinical trials. This review provides brief overview role protein synthesis other functions. With emphasis on L-tryptophan's brain serotonin, details are provided uses L-tryptophan, particularly depletion, trials that have conducted using supplementation. The ability to change rates serotonin by manipulating concentrations serum tryptophan foundation...

In the research literature, aggressive behavior has traditionally been classified into two distinct subtypes, impulsive or premeditated. Impulsive aggression is defined as a hair-trigger response to provocation with loss of behavioral control. Premeditated planned conscious act, not spontaneous related an agitated state. The present study outlines development clinically useful self-report instrument, Impulsive/Premeditated Aggression Scales (IPAS), designed characterize predominately...

Background: Behavioral impulsivity paradigms vary widely and studies using these measures have typically relied on a single measure used in isolation. As result, comparisons between are difficult, with little consensus regarding which method may be most sensitive to individual differences of different populations. Method: A testing session each four tasks was completed by two groups adolescents aged 13–17: hospitalized inpatients disruptive behavior disorders (DBD; n =22) controls ( =22)....

The purpose of this study was to examine the relationship between laboratory behavioral measured impulsivity (using Immediate and Delayed Memory Tasks) suicidal attempt histories. Three groups adults were recruited, those with either: no previous suicide attempts (Control, n = 20), only a single (Single, or multiple (Multiple, 10). As hypothesized, impulsive responses increased number (Control < Single Multiple). This helps demonstrate how measures can be used discriminate based on histories...

Theories of suicidal behavior suggest that the desire to die can arise from disruption interpersonal relationships. Suicide research has typically studied this individual's perspective quality/frequency their social interactions; however, field attachment may offer another on understanding an patterns and suicide risk. This study examined along with broader family functioning (family adaptability cohesion) among 236 adolescent psychiatric inpatients (n = 111) without 125) histories attempts....

This study assessed the effectiveness of Greiffenstein’s Reliable Digit Span (RDS) score for detection malingered neurocognitive dysfunction. Participants were 54 traumatic brain injury patients referred neuropsychological evaluation. Twenty-four met Slick, Sherman, and Iverson criteria at least probable The control group was composed 30 without external incentive who thus did not meet Slick criteria. All completed digit span test as part either WAIS-R or WAIS-III. RDS scores calculated,...

Both researchers and oversight committees share concerns about patient safety in the study‐related assessment of suicidality. However, concern assessing suicidal thoughts can be a barrier to development empirical evidence that informs research on how safely conduct these assessments. A question has been raised if asking result iatrogenic increases such thoughts, especially among at‐risk samples. The current study repeatedly tested ideation at 6‐month intervals for up 2‐years. Suicidal was...

Previous studies report reduced amplitude of the P300 event-related potential in cocaine-dependent individuals. Cocaine dependence is also associated with increased impulsivity, possibly due to deficits cognitive function that are amplitude. In current study, relationship between cocaine dependence, and were examined. An auditory oddball task along self-report (Barratt Impulsiveness Scale version 11) behavioral laboratory (Immediate Delayed Memory Task) measures impulsivity assessed healthy...

OBJECTIVES: Researchers have clearly implicated impulsivity as having a key role in substance use disorders, and comparisons of self-report measures suggest there are measurably different components impulsive behavior. However comparatively little research has been devoted to understanding the multidimensional nature this construct using laboratory that may be more sensitive tracking changes across time. Many studies measured impulsivity, but methodologically types paradigms often used...

Impulsivity has been conceptualized as influencing the expression of suicidal behavior. Adolescence is a developmental period characterized both by relatively high rate suicide attempts and level impulsivity. The current study examined two behavioral measures (delay reward disinhibition) one self-report measure impulsivity among girls with attempt histories. Girls multiple performed more impulsively on delayed reward, had higher self-ratings depression aggression than either or no attempts....