About
Contact & Profiles
A5010459072
Research Areas
- Nanoparticle-Based Drug Delivery
- Drug Transport and Resistance Mechanisms
- RNA Interference and Gene Delivery
Zhengzhou University
2022
Abstract The development of multidrug resistance (MDR) during cancer chemotherapy is a major challenge in current treatment strategies. Numerous molecular mechanisms, including increased drug efflux, evasion drug-induced apoptosis, and activation DNA repair can drive resistance. Here we have identified the vault protein (MVP) B-cell lymphoma-2 (BCL2) gene as two potential factors driving MDR esophageal squamous cell carcinoma (ESCC). We designed novel versatile self-assembling nanoparticle...
10.1186/s12951-022-01377-x
article
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Journal of Nanobiotechnology
2022-03-28
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