- Atrial Fibrillation Management and Outcomes
- Blood Pressure and Hypertension Studies
- Cardiovascular Function and Risk Factors
- Cardiac Arrhythmias and Treatments
- Heart Rate Variability and Autonomic Control
- Hemodynamic Monitoring and Therapy
- Heart Failure Treatment and Management
- Cardiac Imaging and Diagnostics
- Cardiovascular Health and Disease Prevention
- Cardiovascular and exercise physiology
- Cardiac tumors and thrombi
- Pituitary Gland Disorders and Treatments
- Cardiovascular Syncope and Autonomic Disorders
- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Health and Mental Health
- Cardiovascular Disease and Adiposity
- Global Health Care Issues
- Cardiac Arrest and Resuscitation
- Neuroscience of respiration and sleep
- Body Composition Measurement Techniques
- Non-Invasive Vital Sign Monitoring
- Adrenal and Paraganglionic Tumors
- COVID-19 Clinical Research Studies
- Venous Thromboembolism Diagnosis and Management
Wojskowy Instytut Medycyny Lotniczej
2016-2025
National Academy of Medicine
2013-2025
Wojskowy Instytut Medyczny
2009-2024
Foundation of Cardiac Surgery Development
2019-2024
Military Institute
2014-2023
Leeds Teaching Hospitals NHS Trust
2022
University of Leeds
2022
Poznan University of Medical Sciences
2021
Boehringer Ingelheim (South Korea)
2020
Bayer (Germany)
2020
Abstract The electrophoretic separation of high‐molecular‐weight proteins (> 500 kDa) using polyacrylamide is difficult because gels with a large enough pore size for adequate protein mobility are mechanically unstable. A 1% vertical sodium dodecyl sulfate (SDS)‐agarose gel electrophoresis (VAGE) system has been developed that allows titin (a the largest known SDS subunit 3000–4000 to migrate over 10 cm in ∼13 resolving gel. Such migration gives clear and reproducible isoforms. Proteins...
Abstract Aim Prevention of heart failure (HF) hospitalisations and deaths constitutes a major therapeutic aim in patients with HF. The role telemedicine this context remains equivocal. We investigated whether an outpatient telecare based on nurse‐led non‐invasive assessments supporting remote decisions (AMULET telecare) could improve clinical outcomes after episode acute HF during 12‐month follow‐up. Methods results In prospective randomised controlled trial, left ventricular ejection...
Abstract Aims Transoesophageal echocardiography (TOE) is often performed before catheter ablation or cardioversion to rule out the presence of left atrial appendage thrombus (LAT) in patients on chronic oral anticoagulation (OAC), despite associated discomfort. A machine learning model [LAT-artificial intelligence (AI)] was developed predict LAT based clinical and transthoracic (TTE) features. Methods results Data from a 13-site prospective registry who underwent TOE were used. LAT-AI...
Despite its benefits, oral anticoagulant (OAC) therapy in patients with atrial fibrillation (AF) is associated hemorrhagic complications.
Abstract Background Left atrial (LA) area measurement in 2D echocardiography is commonly used to estimate LA volume, plays a crucial role diagnosis and has prognostic implication wide range of cardiovascular diseases including thromboembolic risk assessment. However, the manual standard does not include quantification ejection fraction (LAEF), an emerging marker outcomes. Purpose To develop test artificial intelligence (AI) model determine LAEF based on apical four-chamber view (A4C) video...
Background: SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2) infection may be associated with impaired cardiac function, especially in severe cases requiring hospitalization. Impedance cardiography (ICG) is a noninvasive method for assessing function. It could useful the early detection of hemodynamic dysfunction, particularly patients course COVID-19. Aim: This study aimed to analyze and compare profiles hospitalized SARS-CoV-2-induced pneumonia those control group. Methods:...
Abstract Limited exercise tolerance and dyspnea in patients with uncomplicated hypertension may pose a diagnostic challenge, particularly when blood pressure is normal assessment results do not support diagnosis of heart failure. The purpose this study was to assess the differences central (cBP) response between females good (non-dyspneic females, nDFs; n = 27) those on exertion (dyspneic DFs; 25). We also investigated relations cBP its dynamics peak oxygen consumption (peak VO 2 ) rate HR)...
The impact of digital health innovations on healthcare is rapidly accelerating. In particular, wearable devices for ambulatory cardiac monitoring are gaining increasing popularity among the general population. A 45-year-old physically active male presented to a cardiology clinic following an episode palpitations and dizziness, which occurred after 24-hour work shift. Shortly symptom onset, he used his Apple Watch perform electrocardiogram, detected monomorphic ventricular tachycardia,...
Telemedicine involves diagnostic, therapeutic and educational services being offered remotely by healthcare professionals to exchange crucial clinical information. It is a rapidly developing form of medical activity part industry, with advanced technologies already available in Poland. Cardiology one the fields which telemedicine methods were pioneered introduced into everyday practice. Some these have become standard procedures for diagnosis treatment some Polish centers, other soon follow....
This study tested the relationship between left atrial (LA) function parameters and results of pulmonary vein isolation (PVI) in patients with fibrillation (AF). Consecutive undergoing PVI for first time 2019 2021 were included. Patients underwent radiofrequency ablation using contact force catheters an electroanatomical system. Follow-up consisted ambulatory visits/televisits 7-day Holter monitoring (at 6 12 months after ablation). On day ablation, all transesophageal transthoracic...
Background: Acromegaly is a rare, chronic disease that involves structural and functional abnormalities of the cardiovascular system. likely affects interactions between system autonomic nervous (ANS). Therefore, assessing relationship sympathetic–parasympathetic balance by analyzing heart rate variability (HRV) hemodynamic profile via impedance cardiography (ICG) may be useful in learning exact nature ANS The purpose this study was to assess possible association HRV ICG-based parameters...
Metabolic syndrome (MetS) is a combination of factors which, collectively, increase cardiovascular risk to greater extent than each them separately. Previous studies showed high be associated with autonomic nervous system dysfunction. The purpose this study was assess the effects antihypertensive treatment on heart rate variability (HRV) in patients hypertension (HTN), depending cooccurrence MetS. 118 uncontrolled HTN were enrolled study. HRV compared among and without MetS (MetS [+], <math...
Introduction . Atrial fibrillation (AF) is associated with high risk of ischemic stroke. The most frequent thrombus location in AF the left atrial appendage (LAA). Transthoracic echocardiography (TTE) a basic diagnostic examination patients (pts) AF. Objectives To analyse relations between echocardiographic features, well-established stroke factors, type AF, and anticoagulation therapy incidence (LAAT). Patients Methods study group consisted 768 pts (mean age, 63 years), admitted to three...
Heart failure (HF) is characterized by high mortality and hospital readmission rates. Limited access to cardiologists restricts the application of guideline-directed, patient-tailored medical therapy. Some telemedicine solutions novel non-invasive diagnostic tools may facilitate real-time detection early HF decompensation symptoms, prompt initiation appropriate treatment, optimal management resources. We describe rationale design AMULET trial, which investigates effect comprehensive...