A5026001650- Cervical Cancer and HPV Research
- Gestational Trophoblastic Disease Studies
- Endometrial and Cervical Cancer Treatments
- Prenatal Screening and Diagnostics
- Genital Health and Disease
- Ovarian cancer diagnosis and treatment
- Global Cancer Incidence and Screening
- Ectopic Pregnancy Diagnosis and Management
- Congenital Diaphragmatic Hernia Studies
- Reproductive tract infections research
- Endometriosis Research and Treatment
- Multiple and Secondary Primary Cancers
- Head and Neck Cancer Studies
- Uterine Myomas and Treatments
- Teratomas and Epidermoid Cysts
- Health and Wellbeing Research
- Cancer-related molecular mechanisms research
- Cancer Risks and Factors
- Neurofibromatosis and Schwannoma Cases
- Colorectal and Anal Carcinomas
- Minimally Invasive Surgical Techniques
- Genetic factors in colorectal cancer
- Ureteral procedures and complications
- Peripheral Nerve Disorders
Siriraj Hospital
2017-2025
Mahidol University
2017-2025
Community Link
2020
Brigham and Women's Hospital
2020
Harvard University
2020
ABSTRACT To improve access to colposcopy for women with abnormal cervical cancer screening results, this study evaluated the diagnostic accuracy of internally developed Siriraj portable digital cervicography device detecting intraepithelial neoplasia grade 2 or worse (CIN2 + ) and compared its performance standard colposcopy. Consenting eligible underwent examination using both Images from each method were independently by a physician blinded other images histology results. The primary...
To study patterns of abnormal cervical cancer screening in women aged >60 years and explore the risk predictors intraepithelial neoplasia grade 2 or worse (CIN2+). This retrospective cohort examined 1,596 with results from eight Thai centers. Those who underwent hysterectomy were excluded. Patient characteristics, previous current results, histopathology data collected analyzed. Mean age was 68.2±7.2 years. The normal cytology positive high-risk human papillomavirus (0.9%), atypical squamous...
Abstract Background and Objectives The objective of this study is to establish the detection rate sentinel lymph node (SLN) biopsies determine sensitivity false‐negative SLN compared with those systematic pelvic para‐aortic lymphadenectomies in endometrial cancer. Methods This prospective cohort enrolled patients cancer who were scheduled for surgical staging. Patients a history chemotherapy or radiotherapy, an abnormal liver function test, allergy indocyanine green (ICG) excluded. All...
To investigate the distribution of human papillomavirus (HPV) genotypes in low-grade squamous intraepithelial lesion (LSIL) cytology and immediate risk cervical neoplasia grade 2 or higher (CIN2+) lesions. This prospective cross-sectional study enrolled women aged ≥21 years that were diagnosed with LSIL at Siriraj Hospital (Bangkok, Thailand) during 2017-2019. Anyplex II HPV testing was performed to detect 14 high-risk cases prior colposcopy-directed biopsy. In total, 318 patients included...
To compare the clinical performance of high-risk human papillomavirus (hrHPV) DNA detection between urine and cervical samples collected from same patient for CIN2+ lesions (high-grade squamous intraepithelial or cancer lesions). The secondary objectives were to evaluate agreement among hrHPV genotypes satisfaction sample collection.This prospective cross-sectional study enrolled 96 women with abnormal cytology who attended colposcopy clinic at Siriraj Hospital (Bangkok, Thailand) July 2016...
To compare clinical characteristics and identify factors predictive of resistance to initial treatment with methotrexate-folinic acid (MTX-FA) in women low-risk gestational trophoblastic neoplasia (GTN).Retrospective chart reviews were conducted patients diagnosed GTN who treated MTX-FA at Siriraj Hospital between 2002 2018. Demographic data, disease characteristics, response, toxicity, data the subsequent pregnancy collected analyzed. Groups responsive or resistant compared. Stepwise...
Objective: To evaluate the spontaneous regression rate and its associated factors of low grade intraepithelial lesionsafter colposcopy in Thai women.Material Methods: A retrospective study data women, not younger than 21 years old with liquidbased cervical cytology atypical squamous cells undetermined significance (ASC-US) or low-grade lesions (LSIL), who had received colposcopic examination histologically proven neoplasia 1 (CIN1) human papillomavirus (HPV) infection. All patients underwent...
OBJECTIVE: To compare the proportion of cervical intraepithelial neoplasia (CIN) 2 or worse pathology among different risk strata according to ASCCP when applied in women who had atypical squamous cells undetermined significance (ASC-US) low-grade lesion (LSIL) cytology; assess performance colposcopy; and independent predictors for detected CIN pathology. METHODS: This is a secondary analysis previous prospective study, which included Thai with ASC-US LSIL cytology underwent high-risk human...
Objective: To investigate the rates of and factors associated with cervical cancer screening overuse underuse, attitude towards human papillomavirus (HPV) self-sampling among hospital staffs.
 Materials Methods: This cross-sectional study included female staff undergoing an annual health check-up. A questionnaire was used to collect sociodemographic characteristics, indication for screening, reasons decision, toward HPV self-sampling. Screening defined as having without while underuse...
Abstract We conducted a prospective study to evaluate the prevalence of high-risk human papillomavirus (hr-HPV) positivity in women with atypical squamous cells undetermined significance (ASC-US). Additionally, we assessed association hr-HPV pathology high-grade intraepithelial lesions or worse (HSIL + ) and risk subsequent detection lesions. A total 376 were included, 242 (64.4%) exhibiting positivity. The predominant HPV genotypes 16, 52 58. Factors associated immediate HSIL included...
To compare attitudes toward self-sampling for human papillomavirus (HPV) testing before and after specimen collection in women undergoing colposcopy. The factors associated with the pre-sampling attitude were also studied.
Gestational trophoblastic neoplasia (GTN) is an uncommon group of pregnancy-related malignancies. Delayed diagnosis a prognostic factor for worse outcome. GTN even harder to diagnose if the site metastasis uncommon. The reported case 27-year-old G2P1A1 woman who presented our center with acute transient generalized tonic-clonic seizure. She had developed hemoptysis 2 preceding weeks, which been treated as pneumonia. then noticed multiple gum lesions and vaginal spotting 1 week before her...
Purpose To evaluate the performance of Siriraj liquid‐based solution for human papillomavirus (HPV) DNA testing compared with standard transport media. Methods This cross‐sectional study enrolled 217 women aged 30 years or older who attended cervical cancer screening had abnormal cytology, were diagnosed at Department Obstetrics‐Gynecology, Hospital from March 2015 to January 2016. We excluded patients a history any procedures, hysterectomy, previous treatment pelvic irradiation...
Objective: Obturator nerve schwannoma is an uncommon pelvic tumor and, therefore, usually overlooked as a probable diagnosis per initial, preoperative, radiologic evaluations. This leads to unanticipated difficult intraoperative management in narrow operative field, surrounded by vital organs. report describes patient with obturator who presented mass and underwent surgical evaluation for possible ovarian malignancy. Case presentation: A 58-year-old woman, presenting asymptomatic right...
<h3>Introduction</h3> This study was to explore the prevalence and associated factors with high-grade lesions or cancer in women aged > 60 years abnormal cervical screening. <h3>Methods</h3> Medical records of who had screening from 8 Thai centers during 2009–2021 were retrospectively reviewed. Baseline characteristics, prior current subsequent histopathology collected. Logistic regression analysis performed identify cancer. <h3>Results</h3> A total 1,622 included. The mean age 68.2±7.2...