A5076193918- Fungal and yeast genetics research
- Advancements in Battery Materials
- Insect and Arachnid Ecology and Behavior
- biodegradable polymer synthesis and properties
- Dendrimers and Hyperbranched Polymers
- Alzheimer's disease research and treatments
- Antifungal resistance and susceptibility
- Supramolecular Self-Assembly in Materials
- Botulinum Toxin and Related Neurological Disorders
- Prion Diseases and Protein Misfolding
- Fungal Infections and Studies
- Transgenic Plants and Applications
- Advanced battery technologies research
- Proteins in Food Systems
- Plant and fungal interactions
- Nerve injury and regeneration
- Parkinson's Disease Mechanisms and Treatments
- Catalytic Alkyne Reactions
- Advanced Polymer Synthesis and Characterization
- Adsorption and biosorption for pollutant removal
- Liquid Crystal Research Advancements
- Hydrogen Storage and Materials
- Plant Reproductive Biology
- Enzyme Production and Characterization
- Hydrogels: synthesis, properties, applications
The University of Sydney
2013-2023
Robert Bosch (Australia)
2016
Australian Nuclear Science and Technology Organisation
2008-2009
University of Waterloo
2008
An amino-functionalised metal–organic framework (MOF), aluminium aminoterephthalate (amino-MIL-101(Al)), has been applied to the adsorptive removal of dyes (cationic methylene blue, MB, and anionic methyl orange, MO) from aqueous solutions in order examine effect amino group on sorption behaviour. Adsorption isotherms thermodynamic studies indicated spontaneous adsorption MB with a maximum capacity at 30 °C (762 ± 12 mg gMOF−1) higher than those observed for other MOFs most materials. In...
The synthesis of mesoporous Pt–Cu hollow nanoparticles is reported using copper as seeds in aqueous solution for the first time. show seven times higher specific activity and much better stability towards oxygen reduction reaction than state-of-the-art Pt/C catalysts.
Abstract Rice blast is a devastating disease of rice caused by the fungus Magnaporthe oryzae and can result in loss third annual global harvest. Two hydrophobin proteins, MPG1 MHP1, are highly expressed during infections. These hydrophobins have been suggested to facilitate fungal spore adhesion direct action enzyme cutinase 2, resulting penetration plant host. Therefore mechanistic understanding self-assembly properties these their interaction with 2 crucial for development novel...
Hydrophobins are small proteins secreted by fungi and which spontaneously assemble into amphipathic layers at hydrophilic-hydrophobic interfaces. We have examined the self-assembly of Class I hydrophobins EAS∆15 DewA, II hydrophobin NC2 an engineered chimeric hydrophobin. These form composed laterally associated fibrils with underlying amyloid structure. two hydrophobins, despite showing significant conformational differences in solution, self-assemble to fibrillar very similar structures...
The effect of PAMAM dendrimers (generations G3, G4 and G5) on the fibrillation alpha-synuclein was examined by fluorescence CD spectroscopy, TEM SANS. inhibited this increased both with generation number concentration. SANS showed structural changes in formed aggregates alpha-synuclein--from cylindrical to dense three-dimensional ones--as concentration increased, account inhibitory effect. also effectively promoted breaking down pre-existing fibrils alpha-synuclein. In processes--that is,...
The rodlet structure present on the Aspergillus fumigatus conidial surface hides conidia from immune recognition. In spite of essential biological role rodlets, molecular basis for their self-assembly and disaggregation is not known. Analysis soluble forms conidia-extracted recombinant RodA by NMR spectroscopy has indicated importance disulfide bonds identified two dynamic regions as likely candidates conformational change intermolecular interactions during conversion into amyloid structure....
Abstract Methane pyrolysis (CH 4 → 2H 2 + C) is a promising H production process with zero CO emissions. Utilizing its solid carbon co‐products can make it economically more competitive. Herein, this work demonstrates that graphitic from methane as both cathodes and anodes to enable high‐rate‐performance dual‐carbon batteries (DCBs), outperforming commercial natural synthetic graphite. The graphite purity reach 99.32 97.59 wt%, respectively, using standard high‐temperature thermal treatment...
Abstract Mutation, irregular expression and sustained activation of the Transient Receptor Potential Channel, type Melastatin 4 (TRPM4), have been linked to various cardiovascular diseases. However, much remains unknown about structure this important ion channel. Here, we purified a heterologously expressed TRPM4-eGFP fusion protein investigated oligomeric state in detergent micelles using crosslinking, native gel electrophoresis, multi-angle laser light scattering electron microscopy. Our...
Abstract A new strategy for the preparation of well‐dispersed clays in a polymer matrix by spray‐drying method is presented. Scanning electron microscopy and transmission measurements show that process produces clay/polymer microspheres which clay trapped state throughout matrix. The have been successfully extruded into clay/poly(methyl methacrylate) nanocomposite bulk structures without any perturbation nanostructure original microspheres. Transmission small‐angle X‐ray scattering particles...
Hydrophobins are remarkable proteins due to their ability self-assemble into amphipathic coatings that reverse surface wettability. Here, the versatility of Class I hydrophobins EASΔ15 and DewY in diverse nanosuspension coating applications is demonstrated. The shown coat or emulsify a range substrates including oil, hydrophobic drugs, nanodiamonds alter solution behavior. Surprisingly, while confer new properties, only subset found be resistant hot detergent treatment, feature previously...
This paper describes the supramolecular assembly of arborescent (dendrigraft) copolymers in solution. The dendritic remained as unimolecular (nonassociated) micelles toluene at temperatures above critical self-assembly temperature (cst) but aggregated into structures with a diameter few micrometers below cst. Small-angle neutron scattering (SANS) measurements revealed that P2VP shell was swollen aggregates obtained cst had spherical topology and relatively uniform size according to electron...
Alzheimer's disease is imposing a growing social and economic burden worldwide, effective therapies are urgently required. One possible approach to modulation of the outcome use small molecules limit conversion monomeric amyloid (Aβ42) cytotoxic oligomers fibrils. We have synthesized modulators assembly that unlike others studied date: these compounds act primarily by sequestering Aβ42 monomer. provide kinetic nuclear magnetic resonance data showing perphenazine conjugates divert monomer...
Dual Carbon Batteries Methane pyrolysis that directly splits methane into hydrogen and solid carbon is a promising no-emission production method. In article number 2300495, Yuan Chen co-workers show its graphitic by-products can serve as efficient anode cathode materials to enable high-performance dual-carbon batteries.
Back Cover: Dendrimer PAMAM interferes with amyloid pathway of α‐synuclein in two ways: it inhibits fibrillation early stages and dissociates existing fibrils. The redirection the protein by dendrimers from pathological forms to non‐toxic aggregates or preservation native conformation, especially their ability dissociate fibrils offer therapeutic outlook for Parkinson's disease. Further details can be found article A. Rekas, V. Lo, G. E. Gadd, R. Cappai, S. I. Yun on page 230.
A variety of propargylamines can be prepared in excellent yields by a three-component coupling reaction catalyzed gold(III)-salen complexes water. The chiral substituents on cyclic secondary amines transferred the chirality to newly formed sp3 carbon center. When prolinol derivatives were employed as amine component, diastereoselectivity was achieved (up 99:1). Prolinol bearing bulky diphenyl groups afforded 5 83% yield with 99:1 dr. Sensitive functionalities such esters are not tolerated....