Polybrominated diphenyl ethers (PBDEs) are widely used as additive flame retardants in plastics, soft furnishings, electrical and electronic equipment, insulation the indoor environment, may be released indoors via volatilization or dusts. The penta-and octa-brominated mixes now banned most parts of Europe, phasing out their use has recently begun North America. This study follows a previous investigation into air levels PBDEs. House dust was analyzed from family vacuum cleaners 68 same 74...

The polybrominated diphenyl ethers (PBDEs) are widely used as flame retardants in plastics of soft furnishings, TV sets and computers, insulation the indoor environment. penta-BDEsnow banned most parts Europe but still North Americaare additive that may be released to environment via volatilization or dusts. In this study, investigate general population PBDE exposure, air was sampled 74 randomly selected homes Ottawa, Canada at seven outdoor sites during winter 2002−3, using polyurethane...

Perfluorinated alkyl sulfonamides (PFASs) which are used in a variety of consumer products for surface protection were investigated through comprehensive survey indoor air, house dust, and outdoor air the city Ottawa, Canada. This study revealed new information regarding occurrence source strength several PFASs including N-methylperfluorooctane sulfonamidoethanol (MeFOSE), N-ethylperfluorooctane (EtFOSE), sulfonamide (EtFOSA), sulfonamidethylacrylate (MeFOSEA). Passive samplers consisting...

Settled house dust (SHD) may be a significant source of children's indoor exposure to hazardous substances including polycyclic aromatic hydrocarbons (PAHs). In this study, organic extracts sieved vacuum cleaner from 51 homes were examined for the presence 13 PAHs via GC/MS. found in all samples with levels total ranging between 1.5 and 325 µg g−1. The PAH concentrations SHD correlated information contained corresponding household questionnaires. Analyses showed negatively associated...

Exposure to residential volatile organic compounds (VOCs) is ubiquitous in homes, and may influence respiratory health with important public implications. To investigate the association between VOCs measured indoor air lung function Canadian population Cycle 2 of Health Measures Survey - a based cross-sectional survey designed be representative was carried out 2009 2011. Of 84 measured, 47 were detectable at least 50% homes ten negatively associated function: decanal, 2-furancarboxaldehyde,...

We have examined several emerging brominated flame retardants (BFRs) including 2-ethyl-1-hexyl-2,3,4,5-tetrabromobenzoate (TBB), bis(2-ethylhexyl) tetrabromophthalate (TBPH), 1,2-bis(2,4,6-tribromophenoxy) ethane (BTBPE), 4,5,6,7-tetrabromo-1,1,3-trimethyl-3-(2,3,4,5-tetrabromophenyl)-indane (OBIND), and decabromodiphenyl (DBDPE) in paired human maternal serum (n = 102) breast milk 105) collected 2008–2009 the Sherbrooke region Canada. Three legacy BFRs were also included study for...

The present study investigated the levels of phthalate esters in a total 86 human milk samples collected among 21 breast-feeding mothers over 6-month postpartum time. Di(2-ethylhexyl) (DEHP) was predominant ester with arithmetic mean value 222 ng g-1 (range: 156−398 g-1, 95% confidence limit), followed by dibutyl (DBP), 0.87 0.62−1.2) g-1. Diethyl (DEP), 0.31 detected only small number samples. Weak correlations between lipid content and were observed. fluctuated period; this may indicate...

A series of perfluorinated compounds (PFCs) including perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) have been recently measured in a variety environmental samples biological matrices. In order to better understand the human exposure routes these chemicals, levels PFOS, PFOA, perfluorobutane (PFBS), perfluorohexane (PFHS) sulfonamide (PFOSA) house dust were investigated. The data revealed correlation between concentrations PFCs percentage carpeting house; older houses...

A passive air sampler comprising a polyurethane foam (PUF) disk impregnated with XAD-4 powder has been developed. This sorbent-impregnated PUF (SIP) builds on previous work using samplers that have effective in spatial mapping studies of nonpolar hydrophobic chemicals, without the need electricity or expensive sampling equipment. In this study, disks and SIP are calibrated for volatile polyfluorinated chemicalsspecifically, fluorotelomer alcohols (FTOHs) perfluoroalkyl sulfonamides (PFASs)....

Dechlorane plus (DP), a flame retardant recently identified in the air and sediment of Great Lakes region, has been detected residential indoor dust city Ottawa, Canada using gas chromatography−mass spectrometry under negative chemical ionization mode. DP was all samples with concentration range 2.3 to 182 ng g-1, except for one sample (5683 g-1) which much higher. The levels were several times higher than those Lakes. presence environments could have implications potential human exposure...

The adverse effects of cigarette smoking on human fertility have been well documented. However, the mechanism(s) underlying detrimental are unknown. Using a novel isolated rat follicle culture assay, we tested hypothesis that benzo-[a]-pyrene (B[a]P), constituent smoke, can inhibit growth. B[a]P levels were quantified in serum and follicular fluid (FF) women undergoing vitro fertilization (IVF) treatment exposed to mainstream smoke (n = 19) non-smokers 10) by gas chromatography mass...

DNA methylation is one of the epigenetic mechanisms that regulates gene expression, chromosome structure, and stability. Our objective was to determine whether system could be a target following in utero postnatal exposure human blood contaminants. Pregnant rats were dosed daily from gestation day 1 until 21 with 2 dose levels either organochlorine pesticides (OCP; 0.019 or 1.9 mg/kg/day), methylmercury chloride (MeHg; 0.02 polychlorinated biphenyls (PCBs; 0.011 1.1 mixture (Mix; 0.05, 5...

A comprehensive, population-based national indoor air survey was conducted in 2009–2011 Canada. total of 84 volatile organic carbons (VOCs) from 3218 houses, 546 apartments, and 93 other dwelling types were measured using passive sampling followed by thermal desorption GC/MS. 12 VOCs both this study the 1992 Canadian study. Arithmetic means 2–5 times lower than those with exception a higher styrene level (1.13 μg·m–3). Comparing geometric 24 showed that levels for comparable to reported...

Airborne levels of selected volatile organic chemicals (VOCs) that are priorities for exposure assessment under the Canadian Environmental Protection Act (CEPA) 1999 were measured in both indoor air and outdoor 75 residential houses, city Ottawa, Canada, during winter 2002/2003. The houses randomly using Ottawa 2001 population census data. VOCs collected on adsorbent tubes by thermal desorption GC/MS. Among 37 monitored, 17 detected with a frequency greater than 80% air; 9 between 30% 80%; 7...

Volatile organic compounds (VOCs) are important pollutants in indoor air. A major survey campaign was carried out over a 24-month period 2012 and 2013 to monitor 88 selected VOCs 3524 Canadian residential homes as part of the Health Measures Survey (CHMS). Among six (limonene, decamethylcyclopentasiloxane, toluene, hexanal, nonanal α-pinene) were present highest concentrations with combined geometric mean value (63.22 μg/m3) accounting for more than half (54%) sum all VOCs. The means...

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTDNA as an Affinity Probe Useful in the Detection and Isolation of Biologically Active Natural ProductsJohn M. Pezzuto, Chun-Tao Che, David D. McPherson, Ji-Ping Zhu, Gulacti Topcu, Clemens A. J. Erdelmeier, Geoffrey CordellCite this: Nat. Prod. 1991, 54, 6, 1522–1530Publication Date (Print):November 1, 1991Publication History Published online1 July 2004Published inissue 1 November...