A5103097059- RNA Research and Splicing
- Prostate Cancer Treatment and Research
- Hormonal and reproductive studies
- Estrogen and related hormone effects
- Cancer-related molecular mechanisms research
- Cancer, Lipids, and Metabolism
- MicroRNA in disease regulation
- Prostate Cancer Diagnosis and Treatment
- RNA modifications and cancer
- Urinary Bladder and Prostate Research
- Circular RNAs in diseases
Tongji Hospital
2015-2021
Tongji University
2015-2021
Evidence supports an important role for miR-203 in the regulation of proliferation, migration and invasion prostate cancer (PCa) cells. However, exact mechanisms PCa are not entirely clear.We examined expression tissues, adjacent normal cell lines epithelial cells by qRT-PCR. Then, effects or Rap1A on adhesion were assayed using CKK-8, analysis, transwell assays. Luciferase reporter assay was performed to assess binding mRNA. Tumor growth assessed subcutaneous inoculation into BALB/c nude...
Long noncoding RNAs (lncRNAs) POU3F3 is overexpressed in esophageal squamous-cell carcinomas, while its role other human cancers unclear. In this study we found that and rho-associated protein kinase 1 (ROCK1) were both increased tumor tissues than adjacent healthy of patients with prostate carcinoma. Expression levels increase the diameter but not significantly affected by lymph node metastasis or distant metastasis. ROCK1 positive correlated tissues. overexpression promoted, knockdown...
Abstract Background Prostate cancer (PCa) and benign prostate hyperplasia (BPH) are commonly encountered diseases in elderly males. The two have some commonalities: both growth depend on hormone respond to antiandrogen therapy. Some studies shown that genetic factors responsible for the occurrences of diseases. There may be a correlation between BPH PCa. Methods GEO database can help determine differentially expressed genes (DEGs) Gene Ontology (GO) term enrichment analysis Kyoto...