A5015555825- Medicinal Plants and Neuroprotection
- Graphene and Nanomaterials Applications
- Curcumin's Biomedical Applications
- Nanoparticle-Based Drug Delivery
- Cancer Treatment and Pharmacology
- Autophagy in Disease and Therapy
- Synthesis and biological activity
- PARP inhibition in cancer therapy
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- Tea Polyphenols and Effects
- Cancer Research and Treatment
- Sirtuins and Resveratrol in Medicine
- HIV Research and Treatment
- Hedgehog Signaling Pathway Studies
- Click Chemistry and Applications
- Cancer-related Molecular Pathways
- Fungal Biology and Applications
- Cancer Cells and Metastasis
- Tryptophan and brain disorders
- Organophosphorus compounds synthesis
- Immune cells in cancer
- Advanced Nanomaterials in Catalysis
University of Calcutta
2017-2024
Abstract A major caveat in the treatment of breast cancer is disease recurrence after therapeutic regime at both local and distal sites. Tumor relapse attributed to persistence chemoresistant stem cells (CSC), which need be obliterated along with conventional chemotherapy. Wedelolactone, a naturally occurring coumestan, demonstrates anticancer effects different cells, although several limitations, mostly ineffective against CSCs. To enhance its biological activity additionally target CSCs,...
Tea is the most popularly consumed beverage in world. Theaflavin and thearubigins are key bioactive compounds of black tea that have anticarcinogenic properties as reported several studies. However, epigenetic potential these has not yet been explored. DNA methyltransferase (DNMT) enzymes induce methylation at cytosine residues play a significant role regulation cancer therapy. The present study explored DNMT inhibitor prevention cancer. Herein, effect theaflavin studied colon cell line...
Background Enhanced inflammatory responses promote tumor progression by activating toll-like receptors (TLRs), which in turn are inhibited C-type lectin like (CTLRs), CLEC12A. Although the presence of CLEC12A acute myeloid leukemia is well established, its role non-hematopoietic tumors still obscure. In hematopoietic tumors, mostly inhibits TLRs and modulates via NF-κB signaling. this study, fate was determined modulating using artemisinin (ART), a FDA-approved anti-malarial drug, known for...
Objective: This study was designed to analyze the combinatorial chemotherapeutic effect of temozolomide (TMZ), most common drug in glioblastoma treatment and a purified carbohydrate (Fr-II) from edible mushroom Pleurotus florida, on human cell lines.Methods: Fr-II by size-exclusion chromatography characterised different mass spectroscopy analysis. Human cells were treated with TMZ, Fr-II, combination TMZ Fr-II. Cell cytotoxicity measured MTT assay, cycle phase distribution determined...
<div>Abstract<p>A major caveat in the treatment of breast cancer is disease recurrence after therapeutic regime at both local and distal sites. Tumor relapse attributed to persistence chemoresistant stem cells (CSC), which need be obliterated along with conventional chemotherapy. Wedelolactone, a naturally occurring coumestan, demonstrates anticancer effects different cells, although several limitations, mostly ineffective against CSCs. To enhance its biological activity...
<div>Abstract<p>A major caveat in the treatment of breast cancer is disease recurrence after therapeutic regime at both local and distal sites. Tumor relapse attributed to persistence chemoresistant stem cells (CSC), which need be obliterated along with conventional chemotherapy. Wedelolactone, a naturally occurring coumestan, demonstrates anticancer effects different cells, although several limitations, mostly ineffective against CSCs. To enhance its biological activity...