Amandine Morot

ORCID: 0000-0003-1957-8251
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About
Contact & Profiles
Research Areas
  • Vibrio bacteria research studies
  • Aquaculture disease management and microbiota
  • Marine and coastal ecosystems
  • Marine Bivalve and Aquaculture Studies
  • Microbial Community Ecology and Physiology
  • Protist diversity and phylogeny
  • Bacterial biofilms and quorum sensing
  • Identification and Quantification in Food
  • Extracellular vesicles in disease
  • Mechanisms of cancer metastasis
  • Circular RNAs in diseases
  • Glioma Diagnosis and Treatment
  • Drug Transport and Resistance Mechanisms
  • Phagocytosis and Immune Regulation
  • Angiogenesis and VEGF in Cancer
  • MicroRNA in disease regulation
  • Fecal contamination and water quality
  • Cancer Cells and Metastasis

Centre National de la Recherche Scientifique
2020-2024

Institut de Recherche pour le Développement
2021-2024

Université de Bretagne Occidentale
2021-2024

Ifremer
2021-2024

Laboratoire des Sciences de l'Environnement Marin
2021-2024

Institut Universitaire Européen de la Mer
2021-2024

Laboratoire de Biotechnologie et Chimie Marines
2022-2024

Université de Bretagne Sud
2021-2023

Inserm
2020

Université Côte d'Azur
2020

Polymicrobial infections threaten the health of humans and animals but remain understudied in natural systems. We recently described Pacific Oyster Mortality Syndrome (POMS), a polymicrobial disease affecting oyster production worldwide. In French Atlantic coast, involves coinfection with ostreid herpesvirus 1 (OsHV-1) virulent Vibrio . However, it is unknown whether consistent populations are associated POMS different regions, how contribute to POMS, they interact OsHV-1 during...

10.1073/pnas.2305195120 article EN cc-by-nc-nd Proceedings of the National Academy of Sciences 2023-09-26

Environmental Vibrio strains represent a major threat in aquaculture, but the understanding of their virulence mechanisms heavily relies on transposition knowledge from human-pathogen vibrios. Here, genetic bases harveyi ORM4 towards European abalone Haliotis tuberculata were characterized. We demonstrated that luxO, encoding regulator quorum sensing system, is crucial for this strain, and its deletion leads to decrease swimming motility, biofilm formation, exopolysaccharide production....

10.1111/1462-2920.15592 article EN Environmental Microbiology 2021-05-14

The Vibrio genus includes bacteria widely distributed in aquatic habitats and the infections caused by these can affect a wide range of hosts. They are able to adhere numerous surfaces, which result biofilm formation that helps maintain them environment. involvement lifestyle virulence pathogens organisms remains be investigated. harveyi ORM4 is pathogen responsible for an outbreak European abalone Haliotis tuberculata populations. In present study, we used dynamic culture technique coupled...

10.3390/microorganisms12010186 article EN cc-by Microorganisms 2024-01-17

Medulloblastoma (MB), the most common brain pediatric tumor, is a pathology composed of four molecular subgroups. Despite multimodal treatment, 30% patients eventually relapse, with fatal appearance metastases within 5 years. The major actors metastatic dissemination are lymphatic vessel growth factor, VEGFC, and its receptors/co-receptors. Here, we show that VEGFC inversely correlated to cell aggressiveness. Indeed, decreases MB proliferation migration, their ability form pseudo-vessel in...

10.1038/s42003-020-01306-4 article EN cc-by Communications Biology 2020-10-16

Nitrogen (N2 ) fixation, or diazotrophy, supports a large part of primary production in oceans. Culture-independent approaches highlighted the presence abundance marine non-cyanobacterial diazotrophs (NCD), but their ecophysiology remains elusive, mostly because low number isolated NCD and lack available genetic tools for these isolates. Here, dual functional approach allowed unveiling affiliated to species Vibrio diazotrophicus. Physiological characterization first mutant obtained so far...

10.1111/1462-2920.16261 article EN cc-by-nc-nd Environmental Microbiology 2022-10-27

Abstract Polymicrobial diseases significantly impact the health of humans and animals but remain understudied in natural systems. We recently described Pacific Oyster Mortality Syndrome (POMS), a polymicrobial disease that impacts oyster production is prevalent worldwide. Analysis POMS-infected oysters on French North Atlantic coast revealed involves co-infection with endemic ostreid herpesvirus 1 (OsHV-1) virulent bacterial species such as Vibrio crassostreae . However, it unknown whether...

10.1101/2023.02.11.528104 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2023-02-11

Abstract Nitrogen (N 2 ) fixation, or diazotrophy, supports a large part of primary production in oceans. Culture-independent approaches highlighted the presence abundance marine non-cyanobacterial diazotrophs (NCD) but their ecophysiology remains elusive, mostly because low number isolated NCD and lack available genetic tools for these isolates. Here, dual functional approach allowed unveiling affiliated to species Vibrio diazotrophicus . Physiological characterization first mutant obtained...

10.1101/2022.07.13.499682 preprint EN cc-by-nc-nd bioRxiv (Cold Spring Harbor Laboratory) 2022-07-13
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