A5101492288- Receptor Mechanisms and Signaling
- Neuropeptides and Animal Physiology
- Molecular Sensors and Ion Detection
- Polymer composites and self-healing
- Cyclopropane Reaction Mechanisms
- Sulfur Compounds in Biology
- Luminescence and Fluorescent Materials
- Catalytic C–H Functionalization Methods
- Chemical Synthesis and Reactions
- Metal-Organic Frameworks: Synthesis and Applications
- Nanoparticle-Based Drug Delivery
- Environmental Chemistry and Analysis
- Analytical Chemistry and Chromatography
- Chemical Synthesis and Analysis
- Nitric Oxide and Endothelin Effects
- Polymer Surface Interaction Studies
- Electrospun Nanofibers in Biomedical Applications
- Nanoplatforms for cancer theranostics
- Luminescence Properties of Advanced Materials
- Radioactive element chemistry and processing
- Synthesis and Biological Evaluation
- Solid State Laser Technologies
- Mesoporous Materials and Catalysis
- Pharmacological Effects of Natural Compounds
- Sulfur-Based Synthesis Techniques
Nanjing Tech University
2020-2023
China Institute of Daily Chemical Industry
2021-2022
Changzhou Vocational Institute of Engineering
2021-2022
Weifang Medical University
2021
University of Arizona
2012-2015
In this article, we synthesized a Yb3+-doped two-dimensional (2-D) upconverting Tb metal-organic framework (Tb-MOF) (hereinafter referred to as Tb-UCMOF) by one-step solvothermal method. The Tb-UCMOF is composed of stacks 2-D nanosheets with an average width distributed between 250 and 300 nm, these can be exfoliated simple liquid ultrasound structural characteristics flaky particle accumulation are confirmed the type IV adsorption-desorption isotherm H3-type adsorption hysteresis loop,...
A ratiometric nitenpyram (NIT) upconversion luminescence sensor UCNPs–PMOF was fabricated from a metal–porphyrin organic framework (PMOF) and pretreated UCNPs.
Biomass bifunctional polyamide elastomers (BbPEs) were successfully prepared from dimer acid (DA), trimer (TA), and triethylenetetramine with shape memory self-healing abilities. In the composition structure of BbPEs, vast hydrogen bonds formed among amide different segments endowed BbPEs ability. At room temperature, mechanical properties can be restored to 49% original condition after healing for 2 h. addition, physical chemical cross-linking BbPE preferable properties. The tensile...
Glycosylated β-endorphin analogues of various amphipathicity were studied in vitro and vivo mice. Opioid binding affinities the O-linked glycopeptides (mono- or disaccharides) unglycosylated peptide controls measured human receptors expressed CHO cells. All pan-agonists, to μ-, δ-, κ-opioid low nanomolar range (2.2–35 nM Ki's). The glycoside moiety was required for intravenous (i.v.) but not intracerebroventricular (i.c.v.) activity. Circular dichroism NMR indicated degree helicity H2O,...
Glycopeptides related to β-endorphin penetrate the blood-brain barrier (BBB) of mice produce antinociception. Two series glycopeptides were assessed for opioid receptor binding affinity. Attempts alter mu-selectivity [D-Ala(2),N-MePhe(4),Gly-ol(5)]enkephalin (DAMGO)-related by altering charged residues amphipathic helical address unsuccessful. A pan-agonists was evaluated antinociceptive activity (55 °C tail flick) in mice. flexible linker required maintain activity. Circular dichroism (CD)...
Various catalysts were used to catalyze the ethoxylation reaction of C12-14 primary alcohols with ethylene oxide. Alcohol ethoxylates a ratio oxide/substrate near 3 synthesized. The influenced rate, molecular weight distribution adducts, and formation byproducts. physicochemical properties obtained using different catalytic systems analyzed, their functional properties, i.e., wetting permeation, investigated. results showed that products MCT-09 NAE-03 had narrower oligomer excellent compared...
The atom transfer radical polymerization (ATRP)-based synthesis of a pH-sensitive fluorescent polymer (PSDMA-b-POEGMA) was successfully prepared using 3,6-dibromo-isobutyramide acridine (DIA), an initiator with chromophore, to initiate lipophilic monomer 2-styryl-1,3-dioxan-5-yl methacrylate (SDMA) and hydrophilic oligo(ethylene glycol) methyl ether (OEGMA), which contained cinnamic aldehyde acetal structure. With the addition hollow mesoporous silicon (HMS@C18), core-shell nanoparticles...
A novel and efficient C 3 - H vinylation reaction with quinoxalin-2(1 )-one as the substrate, in presence of alkenes, under metal-free conditions, is reported herein. The leads to formation new carbon–carbon bonds that exhibit moderate good reactivities. )-ones, an attractive process can be potentially utilized produce biologically active 3-vinylated )-ones.
A novel and efficient rearrangement of N-tosylhydrazones bearing allyl ethers into trans-olefin-substituted sulfonylhydrazones is proposed. The reaction involves breakage the C-O bond formation C-N bond. can be extended to a wide range substrates, target products synthesized smoothly, regardless presence electron-donating electron-withdrawing groups. proposed strategy new direction in field reactions.