A5083581386- Cancer Immunotherapy and Biomarkers
- Pulmonary Hypertension Research and Treatments
- Cutaneous Melanoma Detection and Management
- Nonmelanoma Skin Cancer Studies
- Virus-based gene therapy research
- Ocular Oncology and Treatments
- Immunotherapy and Immune Responses
- Polyomavirus and related diseases
- Streptococcal Infections and Treatments
- Eicosanoids and Hypertension Pharmacology
- Reconstructive Facial Surgery Techniques
- High Altitude and Hypoxia
- Corneal Surgery and Treatments
- Cancer survivorship and care
- COVID-19 Clinical Research Studies
- Cancer Diagnosis and Treatment
- Glaucoma and retinal disorders
- Heart Failure Treatment and Management
- Autoimmune and Inflammatory Disorders
- COVID-19 and healthcare impacts
- Antimicrobial Resistance in Staphylococcus
- Cancer, Hypoxia, and Metabolism
- Cancer Research and Treatments
- Histiocytic Disorders and Treatments
- Cutaneous lymphoproliferative disorders research
Columbia University Irving Medical Center
2019-2025
Columbia University
2020-2023
Columbia College
2020
Royal College of Physicians
2020
COVID-19, caused by the SARS-CoV-2 virus, is a major source of morbidity and mortality due to its inflammatory effects in lungs heart. The p38 MAPK pathway plays crucial role release pro-inflammatory cytokines such as IL-6 has been implicated acute lung injury myocardial dysfunction. overwhelming response COVID-19 infection may be disproportionately upregulated activity, explained two mechanisms. First, angiotensin-converting enzyme 2 (ACE2) activity lost during viral entry. ACE2 highly...
Group 1 pulmonary arterial hypertension (PAH) is a rare disease with high mortality despite recent therapeutic advances. Pathogenic remodeling of arterioles leads to increased pressures, right ventricular hypertrophy, and heart failure. Mutations in bone morphogenetic protein receptor type 2 other risk genes predispose disease, but the vast majority non-familial cases remain genetically undefined.To identify new genes, we performed exome sequencing large cohort from National Biological...
Patients with cancer who are infected severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) more likely to develop illness and die compared those without cancer. The impact of immune checkpoint inhibition (ICI) on the severity COVID-19 is unknown. aim this study was investigate whether ICI confers an additional risk for in patients
A 67-year-old woman with no prior ocular history and culture-confirmed streptococcal pharyngitis presented bilateral eye redness, pain movement, swelling, blurry vision. Her condition worsened initial conservative treatment. Repeat imaging indicated scleritis, laboratory test results showed elevated antistreptolysin-O titers. After steroid treatment, her vision returned to baseline symptoms resolved. Acute scleritis is important consider in a patient recent infection despite penicillin...
To describe two cases of retinal hemangioblastoma regression following treatment with belzutifan in patients von Hippel-Lindau syndrome.
Purpose Mohs micrographic surgery (MMS) is a highly efficacious, tissue sparing method of skin cancer removal. Nevertheless, in the months to years after MMS, psychosocial distress has been described. The present study addressed immediate period MMS and assessed frequency risk factors for development depressive symptoms.Methods Subjects undergoing at two physician practices (JL, FS) were included this prospective cohort study. Preoperatively, standardized depression screening, Patient Health...
Introduction: Proper plaque positioning is essential for effective episcleral brachytherapy and can be verified using ultrasound. In this study, we show our center’s protocol intraoperative ultrasound verification of placement present single-center local recurrence data in patients with primary UM involving the choroid and/or ciliary body. We also indicate distance metastasis rate presenting UM. Methods: All who presented to institution body between May 2017 March 2022 treated were enrolled....
Abstract Group 1 pulmonary arterial hypertension (PAH) is a rare disease with high mortality despite recent therapeutic advances. Pathogenic remodeling of arterioles leads to increased pressures, right ventricular hypertrophy and heart failure. Mutations in bone morphogenetic protein receptor type 2 other risk genes predispose disease, but the vast majority non-familial cases remain genetically undefined. To identify new genes, we performed exome sequencing large cohort from National...
Bacteria have long been considered drivers in the development of cutaneous lymphoma, as bacterial antigens may encourage reactive, dysregulated lymphocytic proliferation.1,2 For example, Staphylococcus aureus infection has implicated pathogenesis mycosis fungoides and Sézary syndrome, whereas Borrelia burgdorferi is clinically associated with primary B-cell lymphoma.3-7 Stenotrophomonas maltophilia an opportunist gram-negative bacterium, primarily recognized a cause nosocomial among...