A5027522861- Molecular Sensors and Ion Detection
- Luminescence and Fluorescent Materials
- Advanced biosensing and bioanalysis techniques
- Proteins in Food Systems
- Nanoplatforms for cancer theranostics
- Analytical Chemistry and Sensors
- Animal Genetics and Reproduction
- Photoacoustic and Ultrasonic Imaging
- Microencapsulation and Drying Processes
- Polysaccharides Composition and Applications
- Nitric Oxide and Endothelin Effects
- Phytochemicals and Antioxidant Activities
- Photodynamic Therapy Research Studies
- Electrochemical sensors and biosensors
- Biochemical Analysis and Sensing Techniques
- Neuroscience and Neuropharmacology Research
- Click Chemistry and Applications
- CRISPR and Genetic Engineering
- Chromosomal and Genetic Variations
- Polysaccharides and Plant Cell Walls
- Food composition and properties
- Water Quality Monitoring and Analysis
- Immune Response and Inflammation
- Food Chemistry and Fat Analysis
- Advanced oxidation water treatment
University of Virginia
2017-2025
Shaoxing People's Hospital
2024
University of Louisville
2023
Southern Medical University
2023
Guangdong Provincial People's Hospital
2023
Guangdong Academy of Medical Sciences
2023
Kunming University of Science and Technology
2023
Xi'an Jiaotong University
2006-2023
First People's Hospital of Yunnan Province
2023
East China Normal University
2022
A simple but highly selective colorimetric and ratiometric fluorescent chemodosimeter was designed synthesized to detect fluoride ions (F−) in aqueous solution living cells by virtue of the strong affinity F− toward silicon.
The coumarin-based probe Cu(II)-COT1 was successfully developed for the detection of HNO on basis reduction reaction. In addition, highly selective "turn on" type fluorogenic behavior upon addition Angeli's salt (Na2N2O3) also applied to bioimaging in A375 cells.
Abstract Glioblastoma (GBM) stem-like cells (GSC) promote tumor initiation, progression, and therapeutic resistance. Here, we show how GSCs can be targeted by the FDA-approved drug mibefradil, which inhibits T-type calcium channel Cav3.2. This was highly expressed in human GBM specimens enriched GSCs. Analyses of The Cancer Genome Atlas REMBRANDT databases confirmed upregulation Cav3.2 a subset tumors showed that overexpression associated with worse prognosis. Mibefradil treatment or...
A ferrocene unit is introduced into the salicylaldehyde Rhodamine 6G hydrazone with an alkynyl group to constitute a new chemosensor, R6G-FC, for specifically sensing Cu2+ over other metal ions multisignals. Upon interaction in aqueous solution, R6G-FC expresses detectable fluorescence enhancement along changes UV–vis absorption spectra and electrochemical parameters due binding-induced spirolactam ring-opening process 6G. The complexation between can be carried out within wide pH range...
A rhodamine-based sensor RB-S2 was designed and synthesized by combination of the thiospirolacton chromophore thiophen ring block with high affinity to Hg(2+). Probe exhibits selectivity excellent sensitivity in both absorbance fluorescence detection Hg(2+) aqueous solution. In addition, fluorescent imaging MCF-7 cells is also successfully demonstrated.
It is not well understood how paracrine communication between basal and luminal cell populations in the mammary gland affects tumorigenesis. During ErbB2-induced tumorigenesis, enriched stem cells that represent a subpopulation of exhibit enhanced tumorigenic capacity compared with corresponding progenitors. Transcript profiling tumors derived from tumor-initiating (TIC) revealed preferential loss noncanonical Wnt ligand WNT5A TIC-derived tumors. Heterozygous was correlated shorter survival...
The development of an inorganic–organic hybrid probe to more accurately detect ions in living systems is very challenging but highly desirable. Here we combined upconversion nanoparticles with the electrically active ferrocene group Cu2+ cells. as-prepared displays three different signal changes absorption, emission, and electrochemical behavior, respectively, during ion detection. Moreover, this new has been demonstrated show high stability adaptability. In addition, bioimaging testing...