A5076697134- Curcumin's Biomedical Applications
- Natural Antidiabetic Agents Studies
- Kawasaki Disease and Coronary Complications
- Protein Interaction Studies and Fluorescence Analysis
- Coronary Artery Anomalies
- Glioma Diagnosis and Treatment
- Inflammasome and immune disorders
- Advanced Glycation End Products research
- Epigenetics and DNA Methylation
- Alzheimer's disease research and treatments
- Enzyme function and inhibition
- Proteins in Food Systems
- Biomedical Research and Pathophysiology
- Tryptophan and brain disorders
- Diabetes Treatment and Management
- Viral Infectious Diseases and Gene Expression in Insects
- Cell death mechanisms and regulation
- Kidney Stones and Urolithiasis Treatments
- Protein Structure and Dynamics
- Renin-Angiotensin System Studies
- Trace Elements in Health
- Psidium guajava Extracts and Applications
- MicroRNA in disease regulation
- Therapeutic Uses of Natural Elements
- Free Radicals and Antioxidants
Monash University
2024
Kermanshah University of Medical Sciences
2016-2022
Tabriz University of Medical Sciences
2020
University of Birjand
2017
University of Guilan
2016
The intensive study and investigation of neuroprotective therapy for central nervous system (CNS) diseases is ongoing. Due to shared mechanisms neurodegeneration, a approach might offer benefits across multiple neurological disorders, despite variations in symptoms or injuries. C-Jun N-terminal Kinase 3 (JNK3) found primarily the CNS involved physiological processes such as brain development, synapse formation, memory formation. potential JNK3 target pharmacological development holds promise...
Background: Curcumin is a natural polyphenolic compound with anti-cancer, antiinflammatory, and anti-oxidation properties. Low water solubility rapid hydrolytic degradation are two challenges limiting use of curcumin. </P><P> Objective: In this study, the roles native/modified forms Bovine Serum Albumin (BSA), &#946;-lactoglobulin (&#946;-lg) casein, as food-grade biopolymers also protein chemical modification, in stabilizing on biological activity curcumin were surveyed....
Background: Curcumin, as the substantial constituent of turmeric plant (Curcuma longa), plays a significant role in prevention various diseases, including diabetes. It possesses ideal structure features an enzyme inhibitor, flexible backbone, hydrophobic nature, and several available hydrogen bond (H-bond) donors acceptors. Objective: The present study aimed at synthesizing novel curcumin derivatives further evaluation these compounds for possible antioxidant anti-diabetic properties along...
Objective: one of the main mechanisms in which cancer cells are resistant to chemotherapy drugs and therapeutic strategies is resistance apoptosis due these anticancer factors. Regulating expression genes through epigenetics, especially regulation methylation, key aspects regulating gene function genes, also regulated by pathways pathway apoptosis. The epigenetic regulatory phenomenon can undergo a change induces against purpose present scrutiny was defined probe effect subtoxic prednisolone...
Glioblastoma multiforme (GBM) is the most malignant primary brain tumor found in humans. Mutations isocitrate dehydrogenases 1 (IDH1R132H) was observed GBM. GBMs with IDH1R132H have longer patient survival compared to wild-type IDH1 and identifying mechanism of this can contribute development a new treatment for To investigate role on gene expression, we incorporated three expression arrays from GEO including GSE36245, GSE131837, GSE122586, one array TCGA which total differences between 293...
Kawasaki disease (KD) is a pediatric inflammatory disorder causes coronary artery complications. The overlapping manifestations with set of symptomatically like diseases such as bacterial and viral infections, juvenile idiopathic arthritis, Henoch-Schönlein purpura, infection unknown etiology, group-A streptococcal adenoviral incomplete KD could lead to misdiagnosis the disease.In present study, we applied weighted gene co-expression network analysis (WGCNA) identify modules co-expressed...
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Diabetes is a group of metabolic disorders characterized by high blood sugar level over prolonged period time. Inhibition carbohydrate hydrolyzing enzymes leads to decrease in the absorption glucose which considered as one effective managements diabetes mellitus. Vegetable, fruit, milk, and fish are good sources riboflavin (RF) vitamin B5 with versatile health benefits. The well-adapted structural features these compounds for inhibition/activation include several available hydrogen bond...