A5002148428- Astrophysical Phenomena and Observations
- Pulsars and Gravitational Waves Research
- High-pressure geophysics and materials
- Cancer-related molecular mechanisms research
- RNA modifications and cancer
- Epigenetics and DNA Methylation
- Mechanics and Biomechanics Studies
- Gamma-ray bursts and supernovae
- Astrophysics and Cosmic Phenomena
National Astronomical Observatories
2018-2025
Chinese Academy of Sciences
2018-2025
University of Chinese Academy of Sciences
2018-2025
Astronomy and Space
2025
For cancer diagnosis, many DNA methylation markers have been identified. However, few studies tried to identify diagnose diverse types simultaneously, i.e., pan-cancers. In this study, we differentiate samples from the respective normal in We collected whole genome data of 27 containing 10,140 and 3386 samples, divided all into five sets, including one training set, validation set three test sets. applied machine learning markers, specifically, constructed diagnostic prediction models by...
Abstract Aiming at a general description of four basic solutions describing the accretion processes, i.e., Shakura-Sunyaev thin disc (SSD), Shapiro-Lightman-Eardley solution (SLE), slim disc, and advection-dominated flow (ADAF), we present generalized axisymmetric height-averaged equations, where entropy advection, radiation pressure, photon trapping effect are all included self-consistently. Our can reproduce ADAF, SLE, SSD, branches in wide range rates from sub- to super-Eddington...
Whole-genome bisulfite sequencing generates a comprehensive profiling of the gene methylation levels, but is limited by high cost. Recent studies have partitioned genes into landmark and target suggested that expression levels capture adequate information to reconstruct levels. This inspired us propose level promoters in might be promoter genes, which would eventually reduce cost profiling. Here, we deep learning model called Deep-Gene Promoter Methylation (D-GPM) predict whole-genome based...
A thermal soft X-ray component is often detected in low-level accreting neutron stars (NSs), but not stellar-mass black holes (BHs). In this paper, we investigate the origin of such a framework self-similar solution advection-dominated accretion flow (ADAF) around NSs. It assumed that fraction, $f_{\rm th}$, energy transferred onto surface NS thermalized at as photons to be scattered ADAF. We self-consistently calculate structure and corresponding emergent spectrum ADAF by considering...
ABSTRACT It is widely accepted that X-ray emission in luminous active galactic nuclei (AGNs) originates from hot corona. To prevent the corona overcooling by strong emission, steady heating to essential, for which most promising mechanisms magnetic reconnection. Detailed studies of coupled disc and corona, frame field transferring accretion-released energy reveal thermal electrons can only produce spectrum with $\Gamma _{\rm 2-10\, keV}\gt 2.1$, an inevitable consequence radiative coupling...
ABSTRACT When neutron star low-mass X-ray binaries (NS-LMXBs) are in the low-level accretion regime (i.e. $L_{\rm X}\lesssim 10^{36}\ \rm erg\ s^{-1}$), flow inner region around NS is expected to exist form of hot flow, e.g. advection-dominated (ADAF) as that black hole binaries. Following our previous studies Qiao & Liu (2020a, b) on ADAF NSs, this paper, we investigate radiative efficiency NSs with an detail, showing much lower than $\epsilon \sim {\dot{M} GM\over R_{*}}/{\dot{M}...
Low-mass X-ray binaries (LMXBs) with neutron stars show quite different features which depend on the rate of mass transfer from donor star. With a high Z sources are in persistent soft spectral state, moderate transient Atoll have outburst cycles like black hole binaries. The observations document very long recurrence times for number sources. We follow our computations evolution accretion disc until onset ionization instability. For low accumulation matter is essentially reduced due to...
ABSTRACT It is commonly believed that accretion discs are truncated and their inner regions described by advection dominated flows (ADAFs) in the hard spectral state of black hole X-ray binaries. However, increasing occurrence a relativistically blurred Fe K α line together with continuum points to existence thin disc located near innermost stable circular orbit (ISCO). Assuming via an ADAF extending 100 Schwarzschild radii, which supplied either stellar wind from companion star or resulting...
Observationally, an anti-correlation between the X-ray photon index $\Gamma$ (obtained by fitting spectrum 0.5 and 10 keV with a single power law) luminosity $L_{\rm 0.5-10keV}$, is found in neutron star low-mass binaries (NS-LMXBs) range of 0.5-10keV}\sim 10^{34}-10^{36}\ \rm erg\ s^{-1}$. In this paper, we explain observed 0.5-10keV}$ within framework self-similar solution advection-dominated accretion flow (ADAF) around weakly magnetized NS. The ADAF model intrinsically predicts...