A5003892059- Click Chemistry and Applications
- Synthesis and Biological Evaluation
- Synthesis and biological activity
- Crystallization and Solubility Studies
- X-ray Diffraction in Crystallography
- Chemical Synthesis and Analysis
- Synthesis and Characterization of Heterocyclic Compounds
- Synthesis and Catalytic Reactions
- Molecular Sensors and Ion Detection
- Metal complexes synthesis and properties
- Peptidase Inhibition and Analysis
- Crystal structures of chemical compounds
- Multicomponent Synthesis of Heterocycles
- Organometallic Compounds Synthesis and Characterization
- Advanced biosensing and bioanalysis techniques
- Chemistry and Chemical Engineering
- Computational Drug Discovery Methods
- Luminescence and Fluorescent Materials
- Crystallography and molecular interactions
- Organic Chemistry Cycloaddition Reactions
- Synthesis and Characterization of Pyrroles
- Analytical Chemistry and Sensors
- Analytical chemistry methods development
- Electrochemical sensors and biosensors
- Synthesis and Reactions of Organic Compounds
Guru Jambheshwar University of Science and Technology
2016-2025
Chaudhary Charan Singh Haryana Agricultural University
2020-2023
Indian Institute of Technology Indore
2007-2008
Indian Institute of Technology Delhi
2007
The demand for environmental friendly methodologies had shifted the approach of scientific community using easy and green reaction conditions instead hazardous harsh conditions. One suggested approaches, use catalyst remained prime choice free reaction. difficulty in separation homogeneous from product increased attention chemists heterogeneous catalysts. present review summarizes some recent important developments catalysis "click reaction" obtaining 1,2,3-triazoles via Cu-catalyzed...
Biologically active semicarbazone-triazole hybrid molecules designed and synthesized from semicarbazone linked with a terminal alkyne aromatic azides<italic>via</italic>Cu(<sc>i</sc>)-catalyzed cycloaddition reaction. The compounds exhibited potent antibacterial activities against the tested bacterial strains. Computational results are in good agreement the<italic>in vitro</italic>antimicrobial results.
Two libraries of antimicrobial and fluorescent 7-azaindole N -linked benzyl/phenyl 1,2,3-triazole hybrids have been synthesized via Cu (II) catalyzed click reaction. Molecular docking, ADME, Molinspiration DFT studies were also carried out.
Molecular hybridization is one of the recent strategies to synthesize a novel hybrid compound by combining two or more pharmacophoric units. Being linkage process, it focuses on synthesis hybrids which are less toxic and potent than their parent Therefore, nowadays medicinal chemists look forwards for new drugs using molecular hybridization. Chalcones class very important structural motifs in chemistry. Similarly, 1,2,3-triazoles heterocyclic bio-isostere having vast spectrum applications...