The study aimed to evaluate the effects of a 3-week ω-3 PUFA supplementation on serum adipocytokines (i.e., adiponectin, leptin), neuregulin-4 (NRG4) and erythrocyte omega-3 (ω-3) fatty acid content, as well blood antioxidant defense capacity in non-elite endurance runners. Twenty-four runners were randomized into two groups: supplemented group, who received omega free acids extract containing 142 mg EPA, 267 DHA, 12 vitamin E 5 µg D, each administrated at dose six capsules twice day for...

Cytosolic phospholipase A2 (cPLA2) preferentially liberates arachidonic acid (AA), which is known to be elevated in Alzheimer's disease (AD). The aim of this study was investigate the possible relationship between enhanced nitric oxide (NO) generation observed AD and cPLA2 protein level, phosphorylation, AA release rat pheochromocytoma cell lines (PC12) differing amyloid beta secretion. PC12 control cells, cells bearing Swedish double mutation precursor (APPsw), transfected with human APP...

The study was aimed at investigating in vivo and vitro the involvement of cGMP/cGMP-dependent protein kinase (PKG) signaling pathway MPP(+)-induced cytosolic phospholipase A(2) (cPLA(2)) activation dopaminergic neurons. MPP(+) activated neuronal nitric oxide synthase (NOS)/soluble guanylyl cyclase/cGMP mouse midbrain striatum, pheochromocytoma cell line 12 cells, caused an upward shift [Ca(2+)](i) level latter. accompanied by increases total phosphorylated cPLA(2), increased arachidonic acid...

Abstract Background The mechanism of intense pulsed light action on the skin is based selective photothermolysis. delivered to tissue scattered and absorbed by chromophores that absorb a beam radiation specific length. reflectance changes depending physiological state tissue, as shown hyperspectral camera. aim study was assess acne before after (IPL) therapy compare it with healthy skin. Materials methods involved 27 volunteers diagnosed moderate acne. control group consisted 20 people...

Both cytosolic PLA(2) (cPLA(2)) and secretory (sPLA(2)) have been implicated in pathology of cerebral ischemia. However, which isoforms astrocytes is responsible for arachidonic acid (AA) release contributing to their ischemic injury remains be determined. The aim the present study was investigate time-dependent activation cPLA(2) sPLA(2) exposed combined oxygen glucose deprivation (OGD) as well evaluate effectiveness pharmacological blockage a method preventing damage glial cells. It shown...

Microcirculation is the flow of blood through smallest vessels in circulatory system. Capillaries respond to various pathologies much earlier than arteries and veins, changes which indicate that disease already developing. Careful monitoring functioning capillary system often allows detection vivo disorders at an early stage.The aim study was evaluate microcirculation within acne lesions. A noninvasive method semi-quantitative perfusion measurement based on laser speckle contrast analysis...

In the treatment of acne, skin parameters such as sebum secretion, hydration, and content hemoglobin melanin are very important. The values these at appropriate level show maintenance good functionality epidermal barrier impact a given procedure on condition physiology epidermis.The aim study was to evaluate effectiveness anti-acne therapy with IPL by volunteers, well quantify hydration level, in skin.The involved 27 volunteers moderate acne. A series 4 treatments performed intense pulse...

Although it is not a new method, carboxytherapy, which based on intradermal or subcutaneous administration of controlled doses CO2, gaining more and recognition among aesthetic medicine doctors, dermatologists cosmetologists around the world. The consequence applying carbon dioxide directly into tissues associated with an immediate expansion blood vessels, improvement local supply, and, thus, tissue metabolism. It does also support natural regenerative processes. Oxygen growth factors...

Summary In recent years, popularity of radiofrequency (RF) has increased significantly. They are characterized by a low risk complications and relatively high effectiveness. RF use high‐frequency currents causing oscillating motion ions resulting in temperature rise stimulating skin regeneration processes. The aim this work was the thermographic evaluation exposed to different intensity. dynamic thermal imaging used study RF. research carried out two locations with adipose tissue content:...

There is no method that can guarantee effective, quick, and noninvasive removal of tattoo dyes. Laser methods are considered to be the choice. In this study, an attempt was made determine in vitro spectral characteristics selected dyes used permanent makeup tattoos analyze obtained parameters terms laser treatments optimization.

Infrared radiation (IR) has a wide spectrum of both positive and harmful effects on the human body. Negative properties, manifested by increasing level reactive oxygen species (ROS), affect skin ageing acceleration. Other adverse effect infrared exposure is related to its ability significantly penetrate deep into skin, between layers, up blood vessels other tissues warm them up. Due effects, protecting against becomes an important issue.The aim research was verifying usefulness filters...

The ongoing development of the modern society may also be easily noticed in sports. Currently, to able compete at highest level major sporting events, it is essential conduct scientific research estimate individual potential and skill an athlete. aim this study was assess anaerobic endurance men competing running events 400 m/400 m hurdles based on estimation maximum power, as well selected biochemical physiological parameters measured a cardiac stress test supramaximal intensity. Seven...

Purpose: This pilot study aims to explore how skin parameters and body composition impact the tolerance EMS (Electrical Muscle Stimulation) stimuli in women, particularly focusing on pain response varying intensities of EMS. research seeks understand what is essential for optimizing applications. Patients Methods: The involved 16 females (age 35.9 ± 12.3). Body anthropometric measurements were taken, including BMI (Body Mass Index), weight percentage, WHtR (Waist Height Ratio), WHR...

Metatarsalgia – bolesność przodostopia to określenie, które odnosi się do wszystkich zmian w obrębie śródstopia mających przyczyny anatomiczne lub/i biomechaniczne. Przodostopie (obszar rozciągający między linią stawów śródstopno-paliczkowych a stępowo-śródstopnych) najczęstsze miejsce występowania objawów bólowych stopy. Jest obszar, którym może występować kilka powiązanych ze sobą, jak i występujących niezależnie od siebie bardziej powierzchownych skórnych, przez stany zapalne tkanek...

Solar radiation is responsible for changes in the structure of human hair, damages include proteins (65%-95%), lipids, and melanin. The aim was to examine effectiveness sunscreen hair cosmetics whether color affects it.

Sesame oil has been widely used for centuries. It is not only as a kitchen ingredient, but it also to apply the skin. contains natural compounds such sesamol, sesamolin and sesamide, which have ability reflect or absorb certain UV rays. These substances can act filters, helping minimize effects of harmful radiation on The aim study was investigate radioprotective/sun protection properties sesame oil. influence oils from different manufacturers directional reflectance skin analyzed at various...

Background and Objectives: Hallux valgus, one of the most common foot disorders, contributes to formation pain, changes proportions hinders everyday functioning. In this study we wanted verify if kinesiology taping improves hallux valgus affects position as well reducing pain. Materials Methods: Forty feet with were examined parameters measured at three stages: before was applied, just after its application a month use. Measurements taken 3D scanner baropodometric platform. Results: When...

Background: During menopause, a woman’s health often deteriorates, and various methods are sought to prevent this decline. The aim of study was determine the influence SR-WBV training on wellbeing women over 50 years age. Methods: performed twice week for six weeks using SRT Zeptor® Medical-plus noise device. Forty-two were trained D program (7–9 series, lasting 45–60 s each), 23 O (9–11 50–60 each). frequency ranged from 2 8 Hz. Due problems, 12% did not complete protocols. Results:...

Diamond microdermabrasion is one of the most popular cosmetological treatments in field mechanical, controlled abrasion stratum corneum corneocytes. In this study, influence micropeeling on optical properties skin features was investigated. The directional reflectance measured before and after procedure. study involved 15 women aged 23–26. tests were performed surface spots—on forearms, arms lower legs. Post-treatment increased significantly wavelength range 700–2500 nm. remaining ranges it...