Some variants of SARS-CoV-2 are associated with increased transmissibility, disease severity or decreased vaccine effectiveness (VE). In this population-based cohort study (n = 4,204,859), the Delta variant was identified in 5,430 (0.13%) individuals, whom 84 were admitted to hospital. VE against laboratory confirmed infection 22.4% among partly vaccinated (95% confidence interval (CI): 17.0−27.4) and 64.6% CI: 60.6−68.2) fully compared 54.5% 50.4−58.3) 84.4% (95%CI: 81.8−86.5) Alpha variant.

Abstract Background COVID-19 vaccines have been crucial in the pandemic response and understanding changes effectiveness is essential to guide vaccine policies. Although Delta variant no longer dominant, properties will provide knowledge comprehend development of estimate potential over time. Methods In this population-based cohort study, we estimated Comirnaty (Pfizer/BioNTech; BNT162b2), Spikevax (Moderna; mRNA-1273), Vaxzevria (AstraZeneca; ChAdOx nCoV-19; AZD1222), or a combination...

Background Prevalent digital breast tomosynthesis (DBT) has shown higher cancer detection rates and lower recall compared with those of mammography (DM). However, data are limited on histopathologic tumor characteristics interval subsequent round screen-detected cancers for DBT. Purpose To follow women randomized to screening DBT or DM investigate cancers. Materials Methods To-Be is a controlled trial comparing the outcome in organized screening. The included 28 749 women, 22 306 returning 2...

Background Digital breast tomosynthesis (DBT) is considered superior to digital mammography (DM) for women with dense breasts. Purpose To identify differences in screening outcomes, including rates of recall, false-positive (FP) findings, biopsy, cancer detection rate, positive predictive value recalls and biopsies, histopathologic tumor characteristics by density using DBT combined two-dimensional synthetic (SM) (hereafter, DBT+SM) versus DM. Materials Methods This randomized controlled...

To determine the agreement between artificial intelligence software (AI) and radiographers in assessing breast positioning criteria for mammograms from standard digital mammography tomosynthesis.Assessment of was performed by AI four pairs two on 156 examinations women screened Bergen, April to September 2019, as part BreastScreen Norway. Ten were used; three craniocaudal seven mediolateral-oblique view. The evaluated appearance nipple, rotation, pectoral muscle, inframammary fold nipple...

To analyze the association between radiologists' performance and image position within a batch in screen reading of mammograms Norway.We described true false positives negatives by groups positions sizes for 2,937,312 readings performed from 2012 to 2018. Mixed-effects models were used obtain adjusted proportions positive, negative, sensitivity, specificity different positions. We time day weekday included individual variation radiologists as random effects. Time spent was an additional...

Abstract Coronavirus disease 2019 (COVID-19) causes high morbidity and mortality in long-term care facilities (LTCFs). COVID-19 vaccine effectiveness against infection was 81.5% 81.4% among fully vaccinated residents staff LTCFs. The COVID-19-associated death 93.1% residents, no hospitalizations occurred staff.

With the growing prevalence of antimicrobial resistance, there may be a need to strengthen infection prevention and control (IPC) measures in cancer care. When developing clinical guidelines, it is important incorporate patient perspectives.

Abstract Background Due to changes in testing policy and increased use of rapid tests, other indicators for SARS-CoV-2 infections are needed monitor vaccine effectiveness (VE). We aimed estimate VE against COVID-19 sick leave (> 3 days, certified by a medical professional) among employed individuals (25–64-years-old) Norway. Methods performed nationwide cohort study collating data from the Emergency preparedness register COVID-19. used adjusted Cox proportional hazard models with status...

BAKGRUNN Studien beskriver resultater fra infeksjonsovervåkning av covid-19 i sykehjem covid-19-pandemiens første år. MATERIALE OG METODE Alle data studien inngår Beredt C19, et beredskapsregister som samler en rekke datakilder. Vi gikk ut datasettet Helse og omsorg Kommunalt pasient- brukerregister for å definere sykehjemspopulasjon koblet dette til andre datakilder beredskapsregisteret beregne insidensrate, sykehusinnleggelser covid-19-relaterte dødsfall blant sykehjemsbeboere løpet 2020....

Notifications to the Norwegian Institute of Public Health outbreaks in healthcare institutions are mandatory by law, but under-reporting is suspected due failure identify clusters, or because human system-based factors. This study aimed establish and describe a fully automatic, register-based surveillance system clusters healthcare-associated infections (HAIs) SARS-CoV-2 hospitals compare these with notified through mandated outbreak Vesuv.We used linked data from emergency preparedness...

Abstract Surveillance has revealed an increase of multidrug-resistant organisms (MDROs), even in low-prevalent settings such as Norway. MDROs pose a particular threat to at-risk populations, including persons with cancer. It is necessary include populations future infection surveillance. By combining existing data sources, we aimed describe the epidemiology diagnosed cancer Norway from 2008 2018. A cohort was established using Cancer Registry Norway, which then linked notifications...

BAKGRUNN Brystbevarende kirurgi er anbefalt i Norge og internasjonalt ved brystkreft påvist et tidlig stadium. Vi har analysert operasjonsmetode for brystkreftpasienter etter behandlende sykehus, alder diagnose, deteksjonsmetode svulstenes histopatologiske karakteristikk perioden fra 2003 til 2018. MATERIALE OG METODE Informasjon om kvinner alle aldre diagnostisert med infiltrerende (n = 47 004) ble hentet Kreftregisterets databaser. ekskluderte fjernmetastaser diagnose 1 773) de uten...

Abstract Background COVID-19 vaccines have been crucial in the pandemic response and understanding changes effectiveness is essential to guide vaccine policies. Though Delta variant no longer dominant, properties will provide knowledge comprehend development of estimate potential over time. Methods In this population-based cohort study, we estimated against SARS-CoV-2 infections, hospitalisations, intensive care admissions, death using Cox proportional hazard models, across different product...

Objectives: We investigated the epidemiology and impact on mortality of antimicrobial resistance (AMR) in cancer patients with bacteraemia at Oxford University Hospitals (OxUH), UK, Oslo Hospital (OsUH), Norway, during 2008-2018. Design: Historical cohort study. Setting: Regional hospital trusts multiple sites OxUH OsUH. Methods: Patients blood cultures positive for one six pathogen groups a stay within three years following their first diagnosis were followed 30 days after episode....

<title>Abstract</title> Serial measurements of C-reactive protein (CRP) are often taken in hospitals to assess recovery from infection, but their utility remains debated. We examined antibiotic prescribing patterns and association with CRP centile changes a cohort 51,544 suspected bloodstream infections (BSI). Broad-spectrum antibiotics were predominantly used within the first three days after blood culture collection, followed by notable shift narrow-spectrum for Gram-positive infections,...

16.03.2020: Oversiktsartikkel - Hoveddelen av fagkunnskapen om asylsøkeres helse og bruk helsetjenester omhandler psykisk helse, spesielt blant enslige mindreårige asylsøkere, infeksjonssykdommer, tuberkulosescreening.

Objectives To analyse how reader performance varied by time during the day in a population-based breast cancer screening programme. Methods A total of 2,937,312 readings from 148 radiologists and 1,468,656 women were included this study Norway. Number percentages mammographic readings, positive scores, true false negative sensitivity specificity presented for categories each week. Multilevel mixed effect logistic regression models with restricted cubic splines fitted to data, used predict...

We aimed to investigate self-reported pain during screening with digital breast tomosynthesis (DBT). The study was approved by the Regional Committee for Medical and Health Research Ethics in South East of Norway (2015/424). Women completed a questionnaire about experienced directly after examination, August-November 2019. A numeric rating scale (NRS, 0-10) used. Data on compression force (N), pressure (kPa), compressed thickness (mm) were obtained from Digital Imaging Communication Medicine...

Abstract COVID-19 has caused high morbidity and mortality in long-term care facilities (LTCFs) worldwide. We estimated vaccine effectiveness (VE) among residents health workers (HCWs) LTCFs using Cox regressions. The VE against SARS-CoV-2 infection was 81.5 (95%CI: 75.3 – 86.1 82.7%) 81.4% 74.5-86.4%) ≥ 7 days after 2 nd dose staff respectively. associated death 93.1% residents, no hospitalisations occurred HCW ≥7 dose.